Csp2–H functionalization of phenols: an effective access route to valuable materials via Csp2–C bond formation
Giulia Brufani,
Benedetta Di Erasmo,
Chao‐Jun Li
и другие.
Chemical Science,
Год журнала:
2024,
Номер
15(11), С. 3831 - 3871
Опубликована: Янв. 1, 2024
In
the
vast
majority
of
top-selling
pharmaceutical
and
industrial
products,
phenolic
structural
motifs
are
highly
prevalent.
Non-functionalized
simple
phenols
serve
as
building
blocks
in
synthesis
value-added
chemicals.
It
is
worth
mentioning
that
lignin,
being
largest
renewable
biomass
source
aromatic
nature,
mainly
consists
units,
which
enable
production
structurally
diverse
phenols.
Given
their
remarkable
applicability
chemical
value
chain,
many
efforts
have
been
devoted
to
increasing
molecular
complexity
scaffold.
Among
key
techniques,
direct
functionalization
Csp
Язык: Английский
Site-selective nucleophilic substitution reactions of pentafluoropyridine with hydroxybenzaldehydes: synthesis of triarylmethanes comprising perfluoropyridine moieties
New Journal of Chemistry,
Год журнала:
2023,
Номер
47(22), С. 10645 - 10658
Опубликована: Янв. 1, 2023
The
site-selective
nucleophilic
attacks
of
hydroxybenzaldehydes
on
PFP
were
used
to
prepare
several
perfluoropyridinated
(oxy)benzaldehydes.
F-C
alkylation
reaction
arenes/heteroarenes
with
the
derived
products
under
SSA
catalysis
afforded
novel
fluorinated
TRAMs.
Язык: Английский
Synthesis of acyclic triarylmethane-based compounds containing perfluoropyridine subunits using 4,4′-(p-tolylmethylene)bis(2,6-dimethylphenol) as a flexible spacer
Journal of Molecular Structure,
Год журнала:
2023,
Номер
1302, С. 137360 - 137360
Опубликована: Дек. 21, 2023
Язык: Английский
Room‐Temperature ZnBr2‐Catalyzed Regioselective 1,6‐Hydroarylation of Electron‐Rich Arenes to para‐Quinone Methides: Synthesis of Unsymmetrical Triarylmethanes
Chemistry - An Asian Journal,
Год журнала:
2022,
Номер
18(3)
Опубликована: Дек. 12, 2022
A
mild
and
efficient
Zn(II)-catalyzed
regioselective
1,6-hydroarylation
of
para-quinone
methides
(p-QMs)
with
electron-rich
arenes
protocol
is
reported.
variety
are
well
tolerated
under
conditions,
delivering
a
broad
range
triarylmethanes
in
good
to
excellent
yields.
The
present
method
also
works
for
the
hydroarylation
p-QMs
other
nucleophiles,
such
as
aniline,
indole
phenol
derivatives,
offering
corresponding
yields
standard
conditions.
possible
mechanism
formation
C(sp3
)-C(sp2
)
bonds
reactions
has
been
explored
by
step-by-step
control
experiments,
reaction
may
follow
second-order
manner
chemical
kinetic
study.
Язык: Английский