Facile synthesis of bis(indol-3-yl)methane derivatives catalyzed by carboxylic acid functionalized ionic liquid at room temperature: Investigation of photophysical properties, DFT calculations and molecular docking with bovine serum albumin

Tetrahedron, Год журнала: 2024, Номер 153, С. 133845 - 133845

Опубликована: Янв. 23, 2024

Язык: Английский

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Enthalpy-Driven Interaction between Bovine Serum Albumin and Biomass-Derived Low-Melting Mixture Solvents (LoMMSs) for Efficient and Green Purification of Protein

Biomacromolecules, Год журнала: 2025, Номер unknown

Опубликована: Янв. 9, 2025

Green separation of protein (e.g., bovine serum albumin (BSA)) by low-melting mixture solvents (LoMMSs) depends on the underlying mechanism between BSA and LoMMSs. Here, we for first time find that eco-friendly biomass-derived LoMMSs could be potentially used efficient green purification enthalpy-driven interactions. Biomass-derived possess merits high biocompatibility, degradability, abundance, low cost. A single high-affinity binding site via hydrogen bonding van der Waals forces is observed fluorescence thermodynamic analysis. Experimental results from circular dichroism infrared spectra demonstrate addition stabilizes secondary structure protein. This work provides a valuable indication design cost-effective

Язык: Английский

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Catalyst‐Free Synthesis of Substituted Thiazole‐2‐Imine Derivatives in a Mortar, and Their Photophysical Study

ChemistrySelect, Год журнала: 2025, Номер 10(6)

Опубликована: Фев. 1, 2025

Abstract In this study, for the first time we devised a one‐pot telescopic method synthesizing thiazol‐2( 3H )‐imine using mortar‐pestle grinding under solvent‐free conditions. The reaction involves isothiocyanate, primary amine, and α‐bromoketones as precursors. protocol demonstrated broad substrate scope of 19 derivatives confirmed by various spectroscopic techniques. reported approach is simple to operate, has mild conditions, affords desired products in good outstanding yields up 98% 10 20 min. UV‐visible fluorescence techniques were used investigate photophysical characteristics 9 selected derivatives. absorption emission spectra show maximum peak wavelength (λmax) at 295 ̶ 305 nm 369 370 nm, respectively.

Язык: Английский

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Brønsted Acid Ionic-Liquid-Catalyzed Facile One-Pot Synthesis of 1-[(1,3-Benzothiazol-2-ylamino)methyl]-2-naphthols in a Green Medium

Synlett, Год журнала: 2025, Номер unknown

Опубликована: Март 17, 2025

Abstract A rapid, simple, and efficient one-pot protocol has been developed for the sustainable synthesis of 1-[(1,3-benzothiazol-2-ylamino)methyl]-2-naphthols from substituted 2-aminobenzothiazoles, aryl aldehydes, 2-naphthol by using 5 mol% a Bronsted acid ionic liquid as catalyst. This method offers several advantages such broad substrate scope, short reaction time, procedure, benign medium, high yield low catalyst loading. Moreover, can be recycled up to three times without noteworthy loss in catalytic activity.

Язык: Английский

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Synthesis of Dimeric Indoles from Friedel–Crafts Reaction of Indoles with Ketones Catalysed by a Bronsted Acid Ionic Liquid and Their Interactions with BSA and DNA

New Journal of Chemistry, Год журнала: 2024, Номер 48(34), С. 14904 - 14923

Опубликована: Янв. 1, 2024

The synthesis of 35 dimeric indole derivatives was carried out by using [BCMIM][Cl] ionic liquid as a catalyst. binding interaction between bovine serum albumin (BSA)/deoxyribonucleic acid (DNA) and synthesized compounds has been investigated.

Язык: Английский

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Caffeine-catalyzed green synthesis of biscoumarins

Research on Chemical Intermediates, Год журнала: 2024, Номер 50(12), С. 5885 - 5900

Опубликована: Ноя. 2, 2024

Язык: Английский

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A novel anion replaced gemini surfactant: investigation on the primary interaction between gemini surfactant and BSA

Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 247, С. 114434 - 114434

Опубликована: Дек. 5, 2024

Язык: Английский

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