Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(17), С. 1986 - 1992
Опубликована: Апрель 25, 2024
Comprehensive Summary The rhodium‐catalyzed C—H bond activation and cyclization of 3‐oxopent‐4‐enenitriles with alkynes proceed efficiently. Various 2 H ‐pyrans multiple substituents are achieved in good yields through regioselective formation C—O C—C bonds. Transformations involving hydroxy‐alkynoates resulted products a furo[3,4‐ b ]pyran skeleton via further intramolecular ester exchange processes. Different from the traditional “1‐oxatrienes pathway”, this method for synthesis useful possesses certain highlights terms readily available substrates, stable easily derivatized products, gentle convenient operation process, step atom economy.
Язык: Английский