Advances in Colloid and Interface Science, Год журнала: 2024, Номер 331, С. 103233 - 103233
Опубликована: Июнь 12, 2024
Язык: Английский
ChemBioChem, Год журнала: 2024, Номер 25(15)
Опубликована: Май 27, 2024
Abstract Nucleic acids exhibit exceptional functionalities for both molecular recognition and catalysis, along with the capability of predictable assembly through strand displacement reactions. The inherent programmability addressability DNA probes enable their precise, on‐demand accurate execution hybridization, significantly enhancing target detection capabilities. Decades research in nanotechnology have led to advances structural design functional probes, resulting increasingly sensitive robust sensors. Moreover, increasing attention has been devoted accuracy sensitivity DNA‐based biosensors by integrating multiple sensing procedures. In this review, we summarize various strategies aimed at These involve guarantee procedures, utilizing dual signal output mechanisms, implementing sequential regulation methods. Our goal is provide new insights into development more sensors, ultimately facilitating widespread application clinical diagnostics assessment.
Язык: Английский
Процитировано
2
BME Frontiers, Год журнала: 2024, Номер 5
Опубликована: Янв. 1, 2024
Recent advancements in DNA and RNA bioengineering have paved the way for developing stimuli-responsive nanostructures with remarkable potential across various applications. These nanostructures, crafted through sophisticated techniques, can dynamically precisely respond to both physiological physical stimuli, including nucleic acids (DNA/RNA), adenosine triphosphate, proteins, ions, small molecules, pH, light, temperature. They offer high sensitivity specificity, making them ideal applications such as biomarker detection, gene therapy, controlled targeted drug delivery. In this review, we summarize methods used assemble versatile DNA/RNA discuss their emerging structural biology biomedicine, biosensing, delivery, therapeutics. Finally, highlight challenges opportunities rational design of these intelligent bioengineered nanostructures.
Язык: Английский
Процитировано
2
Analytical Chemistry, Год журнала: 2024, Номер unknown
Опубликована: Сен. 19, 2024
Tumor-derived small extracellular vesicle (sEV) microRNAs (miRNAs) are emerging biomarkers for cancer diagnostics. Conventional sEV miRNA detection methods necessitate the lysis of sEVs, rendering them laborious and time-consuming potentially leading to damage or loss miRNAs. Membrane fusion-based
Язык: Английский
Процитировано
2
Analytica Chimica Acta, Год журнала: 2024, Номер 1330, С. 343294 - 343294
Опубликована: Сен. 30, 2024
Язык: Английский
Процитировано
2
Advances in Colloid and Interface Science, Год журнала: 2024, Номер 331, С. 103233 - 103233
Опубликована: Июнь 12, 2024
Язык: Английский
Процитировано
1