Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Ноя. 8, 2024
The
material
acceleration
platform,
empowered
by
robotics
and
artificial
intelligence,
is
a
transformative
approach
for
expediting
discovery
processes
across
diverse
domains.
However,
the
development
of
an
operating
system
platform
faces
challenges
in
simultaneously
managing
experiments
from
multiple
users.
Specifically,
when
it
utilized
users,
overlapping
experimental
modules
or
devices
can
lead
to
inefficiencies
both
resource
utilization
safety
hazards.
To
overcome
these
challenges,
we
present
operation
control
namely,
OCTOPUS,
which
acronym
task
optimization
job
parallelization
via
user-optimal
scheduler.
OCTOPUS
streamlines
experiment
scheduling
optimizes
through
integrating
its
interface
node,
master
node
module
nodes.
Leveraging
process
modularization
network
protocol,
ensures
homogeneity,
scalability,
versatility
platform.
In
addition,
embodies
Job
techniques
mitigate
delays
hazards
within
realistic
operational
environments,
while
closed-packing
schedule
algorithm
efficiently
executes
jobs
with
minimal
waste.
Copilot
developed
promote
reusability
potential
users
their
own
sets
lab
resources,
substantially
simplifies
code
generation
customization
GPT
recommendations
client
feedback.
This
work
offers
solution
encountered
accessed
thereby
will
facilitate
widespread
adoption
processes.
Current Opinion in Electrochemistry,
Год журнала:
2024,
Номер
44, С. 101459 - 101459
Опубликована: Фев. 6, 2024
The
recent
resurgence
of
electrochemical
methods
in
organic
synthesis
has
also
boosted
the
interest
use
flow
electrolysis
cells.
Flow
electrolyzers
are
essential
tools
for
scale
up
processes
due
to
their
high
electrode
surface
area
reactor
volume
ratio,
which
only
depends
on
interelectrode
gap
regardless
size.
Recent
literature
topic
reveals
that
cell
a
very
common
tool
lab
provide
gram
amounts
material,
often
enabling
lower
voltages
and
decrease
supporting
electrolyte
needed
reaction.
Scale-up
multi-100
g
kilogram
been
demonstrated
both
using
numbering
sizing
strategies.
Chemie Ingenieur Technik,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 18, 2025
Abstract
Organic
electrosynthesis
is
a
potential
enabler
for
the
energy
and
resource
transition
in
chemical
industry
as
it
offers
sustainable
alternative
to
homogeneous
or
heterogeneous
processes
producing
fine
commodity
chemicals.
It
utilizes
electricity
instead
of
hazardous
reagents
and,
thus,
also
allows
reducing
product's
carbon
footprint
waste
production.
enables
dynamic
operation
safe
due
galvanostatic
process
control.
Electro‐organic
are
not
yet
widespread.
Engineering
tools
have
been
tailored
electro‐organic
processes,
more
quantitative
model‐based
insight
needed.
Extensive
adoption
requires
efforts
regarding
electrode
material
performance
stability,
scalable
reactor
design,
digitization.
Addressing
these
issues
interdisciplinary
collaboration,
particularly
between
chemists
engineers,
accelerate
implementation
with
high
efficiency
economic
feasibility.
Journal of Materials Chemistry A,
Год журнала:
2024,
Номер
12(7), С. 3933 - 3942
Опубликована: Янв. 1, 2024
Introduction
of
an
SQL
and
Python-based
tool
for
managing
research
data
from
acquisition
to
publication.
The
method
enables
FAIR-compatible
management,
minimizes
user
interaction,
provides
customizability
diverse
domains.
Automated
batch
and
flow
reactors
are
well-established
for
high
throughput
experimentation
in
both
thermal
chemistry
photochemistry.
However,
the
development
of
automated
electrochemical
platforms
is
hindered
by
cell
miniaturization
challenges
difficulties
designing
effective
single-pass
systems.
In
order
to
address
these
issues,
we
have
designed
implemented
a
new,
slug-based
platform.
This
platform
was
successfully
demonstrated
C-N
cross-couplings
E3
ligase
binders
with
diverse
amines
(44
examples),
which
were
subsequently
transferred
continuous-flow
mode
confirmation
isolation.
To
further
validate
versatility
platform,
Design
Experiments
(DoE)
optimization
performed
an
unsuccessful
library
target.
process,
fully
resulted
remarkable
5-fold
increase
reaction
yield.
ECS Advances,
Год журнала:
2023,
Номер
2(4), С. 040502 - 040502
Опубликована: Окт. 2, 2023
Python,
an
open-source,
interpreted
programming
language,
has
emerged
as
a
transformative
force
within
the
scientific
community,
captivating
researchers
with
its
rich
ecosystem
of
packages
and
syntax
that
prioritizes
readability
simplicity.
In
rapidly
evolving
field
electrochemistry,
where
analysis
complex
data
sets,
custom
routines,
theoretical
simulations
are
indispensable,
Python’s
capabilities
have
garnered
significant
attention.
This
review
serves
general
introduction
to
utilization
Python
in
focusing
on
beginners
who
new
concepts.
Abstract
The
necessary
separation
of
anodic
and
cathodic
compartments
in
the
electrochemical
multicomponent
synthesis
alkyl
arenesulfonates
batch
was
overcome
by
transfer
this
reaction
an
undivided
flow
cell.
yield
increased
from
initial
23
%
to
67
optimization
using
Design
Experiments
(DoE).
experiments
were
carried
out
automated
experimental
electrolysis
setup
controlled
automation
software
LABS
(
Laboratory
Automation
Batch
Scheduling
),
open‐source
that
allows
plan
conduct
with
arbitrary,
freely
selectable
setup.
turned
be
stable
provides
reproducible
results.
In
total,
6
examples
are
demonstrated
isolated
yields
up
81
%.
addition,
robust
scalability
a
10‐fold
scale‐up.
The
construction
of
autonomous
chemical
laboratories
is
complex,
laborious,
and
expensive.
It
imperative
to
develop
highly
usable,
flexible,
powerful
development
framework
unify
efforts.
Current
platforms
have
high
adoption
barriers,
whether
through
their
price
adoption,
complexity
implement,
or
limited
implementation
on
diverse
hardware
software
systems.
Furthermore,
there
are
no
studies
date
which
examine
the
practical
usability
current
with
state-of-the-art
scientific
studies.
In
this
work
we
engineer
a
new,
flexible
laboratory
automation
platform
(FLAB)
resolve
these
issues.
With
unique,
user-centric
agile
approach,
eight
different
experimental
studies,
represent
broad
spectrum
activities
in
integration
artificial
intelligence.
By
beginning
generalized,
modular
architecture
Python,
each
study
created
generalized
feature
that
evolved
platform’s
utility
ease
use.
Such
features
include
advanced
methods
for
synchronous
processing,
data
manipulation
user-interface
rapid
prototyping.
Ultimately,
yields
simpler,
more
accessible
toolset
creation
laboratories.
Organic
electrochemical
synthesis
may
be
combined
with
continuous
flow
and
automation
technology.
Here,
the
authors
highlight
benefits
if
such
chemical
engineering
approaches
along
technology
software
directions
taking
organic
chemistry
into
future.
Green Chemistry,
Год журнала:
2024,
Номер
26(13), С. 7443 - 7455
Опубликована: Янв. 1, 2024
The
CTC-Conference
at
Ringberg
brought
scientists
together
to
discuss
their
research
and
brainstorm
a
"moon-shot"
program
align
efforts,
enable
rapid
discoveries,
move
towards
sustainable
circular
economy.
