Antimicrobial properties of carbon “quantum” dots for food safety applications
Journal of Nanoparticle Research,
Год журнала:
2025,
Номер
27(2)
Опубликована: Янв. 31, 2025
Abstract
Carbon
dots
represent
a
rapidly
advancing
and
expanding
research
field,
with
large
number
of
literature
reports
on
their
potential
technological
applications
including
those
relevant
to
food
safety.
In
this
article,
the
dot
samples
prepared
by
deliberate
chemical
functionalization
preexisting
small
carbon
nanoparticles
or
thermal
carbonization
various
organic
precursors
under
different
processing
conditions
are
highlighted
critiqued
for
similarities
differences
in
sample
structure-morphology
properties,
especially
antimicrobial
properties
safety–related
uses.
Also
discussed
representative
recent
examples
use
inactivate
foodborne
pathogens,
disrupt
biofilms
prevent
formation,
extend
shelf
life
products,
which
involve
antibacterial
mechanisms.
Some
perspectives
further
development
dots–based/derived
platform
related
excellent
application
opportunities
safety
provided.
Язык: Английский
Green synthesis of highly luminous lemon juice-based carbon dots for antimicrobial assessment and fingerprint detection
International Journal of Materials Research (formerly Zeitschrift fuer Metallkunde),
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 29, 2025
Abstract
Carbon
dots
are
regarded
as
a
brand
new
class
of
nanostructures
in
the
carbonaceous
family
that
have
piqued
curiosity
researchers
wide
range
bio
applications.
This
work
focuses
on
synthesis
and
characterization
carbon
dots,
well
their
latent
fingerprint
detection
antibacterial/antifungal
capabilities.
Highly
luminous
were
prepared
by
optimizing
simple
hydrothermal
carbonization
settings
at
180
°C
for
12
h
using
lemon
juice
raw
precursor.
The
resulting
product
was
examined
Fourier
transform
infrared
spectroscopy,
scanning
electron
microscopy,
energy
dispersive
X-ray
analysis,
diffractometery,
ultraviolet–visible
spectrophotometer.
as-prepared
found
to
be
extremely
bright
when
excited
under
ultraviolet
light
(
λ
=
365
nm).
presence
oxygen
functionalities
surface
revealed
spectrocopy.
diffraction
pattern
confirmed
amorphous
structure
with
an
average
size
7
nm
determined
Scherrer
equation.
morphology
analysis
exhibited
aggregated
form
irregular
spherical
shapes.
chemical
examination
validated
elemental
makeup
juice-based
dots.
fingerprints
yielded
positive
results.
In
addition,
obtained
displayed
antifungal
antibacterial
activity
against
tested
pathogenic
fungal
bacterial
strains.
Язык: Английский
Nanodot‐Inspired Precise Bacterial Gene Suppression in a Smart Hydrogel Bandage for Underwater Wound Healing
Advanced Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 14, 2025
Abstract
The
complex
and
dynamic
nature
of
aquatic
ecosystems,
particularly
in
marine
environments,
makes
managing
wound
infections
a
significant
challenge
for
individuals
engaged
underwater
activities
organisms.
Although
antibiotics
have
played
critical
role
safeguarding
humans
health,
their
risk
drug
resistance
environmental
impact
present
substantial
obstacles
to
long‐term
sustainability.
Using
fin
rot
disease
turbot
(
Scophthalmus
maximus
)
caused
by
infection
Vibrio
anguillarum
V.
as
model,
new
strategy
is
presented
that
employs
carbon
dot
(CD)‐based
antisense
oligonucleotide
(ASO)
delivery
system,
combined
with
an
adhesive
hydrogel,
achieve
targeted
gene
silencing
healing.
CDs
cause
enhanced
cytoplasmic
membrane
permeability,
efficiently
deliver
ASOs
into
without
requiring
additional
equipment
or
chemical
facilitators.
specific
design
the
ASO
sequence
enables
empA
,
achieving
efficiency
high
71.2%.
An
hydrogel
applied
boost
local
concentration
ASO/CDs
at
sites
seawater,
effectively
sealing
infected
area
preventing
turbot.
This
study
pioneer
bacterial
regulation
using
CD‐based
integrated
bandage,
offering
practical
solutions
diseases.
Язык: Английский
Streamlining Bacterial Gene Regulation via Nucleic Acid Delivery with Gold Nanoclusters
Small,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 24, 2025
Abstract
Delivery
of
exogenous
nucleic
acids
(NAs)
for
gene
regulation
in
bacteria,
bypassing
the
barrier
cell
wall,
is
essential
advancing
fundamental
microbiology
and
genetic
engineering,
treatment
bacterial
diseases.
However,
current
methods
that
rely
on
electrical
or
chemical
interventions
are
limited
by
their
complexity,
specialized
expertise,
laboratory‐specific
instrumentation.
This
study
explores
capability
gold
nanoclusters
(AuNCs)
as
carriers
delivering
small‐interfering
RNA
antisense
oligonucleotides
into
bacteria
targeted
while
shielding
them
from
degradation
during
transport.
By
enhancing
cytoplasmic
membrane
permeability,
AuNCs
enable
efficient
internalization
NAs
both
Gram‐positive
Gram‐negative
exerting
negligible
influence
activity.
It
demonstrated
rationally
designed
can
be
released
within
enabling
~70%
knockdown
mecA
Methicillin‐resistant
Staphylococcus
aureus
(MRSA).
significantly
reduces
MRSA's
antibiotic
resistance
enhances
oxacillin
efficacy.
Furthermore,
successful
silencing
ligA
Escherichia
coli
pilQ
Pseudomonas
aeruginosa
highlights
broad
adaptability
approach
across
diverse
species.
The
AuNCs‐based
next‐generation
NA
delivery
system
has
potential
to
transform
regulation—previously
restricted
laboratory
settings—into
a
versatile
scalable
solution
real‐world
application.
Язык: Английский