SSRN Electronic Journal,
Год журнала:
2022,
Номер
unknown
Опубликована: Янв. 1, 2022
A
new
nitrogen-rich
hyperbranched
polymer
comprising
imidazolium
and
triazole
moieties
used
for
stabilization
of
Pd
nanoparticles.
The
resulting
material,
PolyTZ-IL@Pd
NPs,
was
characterized
with
different
techniques
including
Fourier-transform
infrared
spectroscopy
(FTIR),
X-ray
diffraction
(XRD),
photoelectron
(XPS),
energy
dispersive
X-Ray
(EDX),
transmission
electron
microscopy
(TEM)
analysis.
NPs
has
been
as
an
efficient
catalyst
in
the
reduction
nitroarenes
to
amines
cyanation
aryl
bromides
iodides.
showed
high
stability
recyclability
recycled
at
least
10
times
1-chloro-4-nitrobenzene
5
iodobenzene.
Angewandte Chemie International Edition,
Год журнала:
2022,
Номер
61(25)
Опубликована: Март 31, 2022
Abstract
Bioinspired
supramolecular
architectures
were
used
to
compartmentalize
highly
charged
aqua
scandium
ions
into
chiral
hydrophobic
scaffolds
for
Lewis
acid‐catalyzed
asymmetric
reactions.
Recycling
without
significant
loss
in
catalytic
performance
is
a
formidable
task,
especially
This
because
basic
impurities
derived
from
starting
materials,
products,
and
water
are
competitive
ligands
both
substrate
binding
metal
complexation,
thus
poisoning
the
acids
leading
their
leaching.
Even
when
aniline
used,
architecture
allowed
effective
suppression
of
Sc
3+
leaching
reuse
solvent‐catalyst
couples
ring‐opening
reactions
deactivation.
Application
thia‐Michael
addition
hydroxymethylation
was
also
demonstrated.
The
successful
recycling
environments
underpins
exceptionally
high
robustness
acid
catalyst.
Molecules,
Год журнала:
2022,
Номер
27(17), С. 5611 - 5611
Опубликована: Авг. 31, 2022
Reducing
the
use
of
solvents
is
an
important
aim
green
chemistry.
Using
micelles
self-assembled
from
amphiphilic
molecules
dispersed
in
water
(considered
a
solvent)
has
facilitated
reactions
organic
compounds.
When
performing
micelles,
hydrophobic
effect
can
considerably
accelerate
apparent
reaction
rates,
as
well
enhance
selectivity.
Here,
we
review
micellar
media
and
their
potential
role
sustainable
chemical
production.
The
focus
this
applications
engineered
systems
for
(surface-active
ionic
liquids,
designer
surfactants,
block
copolymers)
media.
Micelles
are
versatile
platform
large
array
chemistries
using
bulk
solvent.
Building
on
foundation,
synthetic
sequences
combining
several
steps
one
pot
have
been
developed.
Telescoping
multiple
reduce
solvent
waste
by
limiting
volume
solvents,
eliminating
purification
processes.
Thus,
particular,
recent
advances
"one-pot"
multistep
achieved
with
medicinal
chemistry
agrochemistry.
Photocatalyzed
also
discussed.
In
addition
to
emphasize
process
(steps
isolate
product
reuse
catalyst).
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(19), С. 12791 - 12798
Опубликована: Сен. 12, 2022
The
direct
transformation
of
aryl
carboxylic
acids
to
nitrile
compounds
is
an
interesting
topic
because
are
not
only
abundant
in
nature
but
also
inexpensive
and
stable.
Here,
the
synthesis
a
series
nitriles
by
palladium-catalyzed
decarbonylative
cyanation
without
base
has
been
achieved.
successful
drug
molecules
Gram-scale
reaction
verify
practicality
operability
this
method
analyzed.
ACS Catalysis,
Год журнала:
2023,
Номер
13(18), С. 12383 - 12390
Опубликована: Сен. 6, 2023
Formation
of
amides,
acids,
and
thioesters
are
readily
fashioned
from
precursor
aryl/heteroaryl
halides
under
micellar
catalysis
conditions
using
W(CO)6
as
a
source
carbon
monoxide.
Loadings
ligated
palladium
catalysts
usually
in
the
0.5
mol
%
range.
Yields
with
iodides
tended
to
be
higher
than
those
bromides.
Applications
targets
pharmaceutical
industry
demonstrated,
cases
Merck
Informer
Library.
Both
E
Factor
calculations
options
for
recycling
aqueous
reaction
medium
presented.
Abstract
A
systematic
investigation
of
the
photoinduced
[6π]‐electrocyclization
reaction
diphenylamine
and
N‐methyldiphenylamine
has
been
carried
out
under
steady‐state
time‐resolved
conditions
in
homogeneous
(cyclohexane,
acetonitrile
methanol)
micellar
solutions
(sodium
dodecyl
sulfate
‐SDS,
cetyltrimethylammonium
chloride‐CTAC
polyethylene
glycol
monododecyl
ether‐Brij
P35).
The
photolysis
such
compounds
both
micro‐heterogeneous
media
afforded
corresponding
carbazoles
almost
quantitative
yield
oxidative
conditions.
Furthermore,
relative
rate
formation
photoproducts
increases
when
moving
from
to
solution,
due
environmental
confined
hydrophobic
core
as
highlighted
by
1D
2D
NMR
(NOESY
DOSY)
spectroscopic
analyses.
Abstract
Regioselective
cyanation
of
quinoxalin‐2(1
H
)‐ones
and
quinoxalines
with
acetone
cyanohydrin
under
aqueous
aerobic
visible‐light
conditions
at
room
temperature
is
described.
Acetone
utilized
as
a
safe
source
for
cyanation.
In
both
cases,
good
functional
group
tolerance
was
observed
very
to
quantitative
yields
products
metal/base/ligand‐free
conditions.
Several
control
experiments
revealed
that,
water
oxygen
from
air
are
crucial
the
efficiency
present
transformation.
These
reactions
proceed
through
radical
pathway
confirmed
by
scavengers.
To
validate
feasibility
process
commercial
syntheses,
three
were
synthesized
gram
scale
optimized
The
conversion
cyanated
into
corresponding
amides
acid
also
performed
pure
obtained
without
column
chromatographic
separation.
Abstract
The
irradiation
of
triphenylamine
(TPA)
under
homogeneous
(cyclohexane,
acetonitrile
and
methanol)
micellar
[sodium
dodecyl
sulfate
(SDS),
cetyltrimethylammonium
chloride
(CTAC)
polyethylene
glycol
monododecyl
ether
(Brij‐P35)]
conditions
has
been
investigated
through
a
combined
steady‐state
time‐resolved
spectroscopic
approach.
Photolysis
TPA
at
254
nm
in
different
media
afforded
N
‐phenylcarbazole
(N−PhCA)
as
the
main
photoproduct,
when
photoreaction
was
carried
out
solution
relative
rate
formation
N−PhCA
found
to
be
faster
than
due
environmental
confined
hydrophobic
core.
On
other
hand,
transient
‐phenyl‐
4a,4b
‐dihydrocarbazole
(DHC
0
)
detected
fully
characterized
via
laser
flash
photolysis.
Finally,
location
within
core
micelle
by
1D
2D
NMR
analyses.
In
the
past
two
decades,
water
has
gradually
become
a
green
and
sustainable
alternative
to
traditional
organic
solvents
which
are
generally
hazardous
waste
productive.
Due
its
safe,
nontoxic,
nonflammable,
cost-effective,
abundant
nature,
been
increasingly
used
in
various
types
of
reactions
ranging
from
conventional
oxidation,
reduction,
addition,
substitution,
condensation,
cyclization
classical
cross-coupling,
CH
activation
more
recent
photoredox,
electrochemical
chemoenzymatic
reactions.
This
chapter
summarizes
(2017-2022)
representative
examples
using
as
solvent
covers
related
reaction
mechanisms
roles
that
plays
certain
Micellar-enabled
aqueous
facilitated
by
surfactants
will
also
be
discussed.
