Temperature-dependent switchable synthesis of imines and amines via coupling of alcohols and amines using pyrrolyl-imine ruthenium catalysts
Journal of Catalysis,
Год журнала:
2024,
Номер
unknown, С. 115895 - 115895
Опубликована: Дек. 1, 2024
Язык: Английский
Dioxygen Controlled Chemodivergent Cross‐Coupling of Primary and Secondary Alcohols Using Noninnocent Azo Aromatic Complexes of Cobalt(II) as Catalysts
ChemCatChem,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 14, 2024
Abstract
Herein,
employing
pincer
like
cobalt
(II)
complexes
containing
redox
noninnocent
azo‐benzimidazole
ligand
a
switchable
and
chemodivergent
catalytic
cross‐coupling
of
primary
secondary
alcohols
is
reported.
The
reactions
are
environmentally
benign
atom
efficient.
It
liberates
water
hydrogen
gas
as
the
only
byproducts.
While
reaction
in
inert
condition
gives
alkylated
ketones,
presence
air
well
lower
temperature
base
loading
selectively
results
unsaturated
ketones.
Both
protocols
have
very
good
functional
group
tolerance.
Thus,
wide
range
substrates
been
found
to
be
effective
for
synthesis
ketones
via
dehydrogenative
alcohols.
Several
control
experiments
kinetic
studies
were
performed
elucidate
pathways.
Язык: Английский
Nitrobenzene and Aniline‐Mediated Direct Olefination of Methyl Substituted N‐Heteroarenes With Benzylic Alcohols
ChemistrySelect,
Год журнала:
2024,
Номер
9(44)
Опубликована: Ноя. 1, 2024
Abstract
Metal‐free,
strong‐base‐free,
and
solvent‐free
synthesis
of
alkenyl
heteroarenes
through
PhNO
2
/PhNH
mediated
direct
olefination
methyl
substituted
N
‐heteroarenes
with
benzylic
alcohols
was
described.
Detailed
mechanistic
studies
indicated
that
in
situ
formed
imine
the
active
intermediate
for
olefination.
protected
from
overoxidation,
PhNH
not
only
acted
as
coupling
partner
formation
imine,
but
also
provides
an
alkaline
condition
generation
enamine
salt.
Gram
scale
reaction
three
pharmaceutically
relevant
conjugated
olefins
were
successful
using
this
methodology.
Язык: Английский