Organic Letters, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 18, 2024
A new iron-catalyzed three-component perfluoroalkylarylation of styrenes with alkyl halides and arenes has been established. Alkyl undergo halogen atom transfer methyl radicals to form in reactions initiated by a combination
Язык: Английский
Current Opinion in Electrochemistry, Год журнала: 2025, Номер unknown, С. 101673 - 101673
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
1
Chemistry - A European Journal, Год журнала: 2024, Номер unknown
Опубликована: Июль 16, 2024
The advancement in electrochemical techniques has unlocked a new path for achieving unprecedented oxidations and reductions of aryl radical precursors controlled selective manner. This approach facilitates the construction aromatic carbon-carbon carbon-heteroatom bonds. In light green merits growing importance this technique chemistry, review aims to provide an overview recent advance generation radicals organized by precursor type, with focus on substrate scope, limitation, underlying mechanism, thereby inspiring future work generation.
Язык: Английский
Процитировано
7
The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(5), С. 2885 - 2894
Опубликована: Фев. 14, 2024
Because of their various reactivities, propargyl acetates are refined chemical intermediates that extensively applied in pharmaceutical synthesis. Currently, reactions between and chlorosilanes may be the most effective method for synthesizing silylallenes. Nevertheless, owing to adaptability selectivity substrates, transition metal catalysis is difficult achieve. Herein, nickel-catalyzed reductive cross-coupling substituted vinyl synthesis tetrasubstituted silylallenes described. Therein, metallic zinc a crucial reductant effectively enables two electrophilic reagents selectively construct C(sp2)–Si bonds. Additionally, Ni-catalyzed mechanism involving radical process proposed on basis deuteration-labeled experiments.
Язык: Английский
Процитировано
5
The Chemical Record, Год журнала: 2023, Номер 23(11)
Опубликована: Июнь 12, 2023
Abstract Harnessing visible‐light in organic synthesis is one of the most effective methods that aligns with green and sustainable chemistry principles hence skyrocketed last two decades. Similarly, three‐component 1,2‐dicarbofunctionalization alkenes alkynes has recently been a great choice to construct complex molecular systems an easy rapid manner. Therefore, light‐induced reactions can be excellent alternative carry out reactions, very recently, chemists across globe have fascinated us their interesting articles. In this present review, we summarized recent advancements area visible light induced till March 2023. We categorized discussion based on catalysts used transformations for better understanding different important aspects these also covered.
Язык: Английский
Процитировано
11
The Chemical Record, Год журнала: 2025, Номер unknown
Опубликована: Фев. 3, 2025
Abstract Owing to their wide utilizations in synthesis and products prevalence numerous natural products, pharmaceuticals functional materials, the alkene difunctionalization methods for selective transformations of olefins are important have attracted much attention form synthetic chemists. Among them, electrochemical reaction is particularly promising has becoming a potent sustainable tool alkenes into vicinal difunctionalized structures organic through simultaneous incorporation two groups. Herein, we summarize recent progress reactions according types as well category radicals over past five years. By selecting remarkable examples, elaborately discussed substrate scope mechanisms olefin reaction.
Язык: Английский
Процитировано
0
Chemical Reviews, Год журнала: 2025, Номер unknown
Опубликована: Март 7, 2025
Constructing chemical bonds under green sustainable conditions has drawn attention from environmental and economic perspectives. The dissociation of (hetero)aryl-halide is a crucial step most arylations affording (hetero)arene derivatives. Herein, we summarize the (hetero)aryl halides activation enabling direct (hetero)arylation trapping reagents construction highly functionalized (hetero)arenes benign conditions. strategies for aryl iodides are classified into (a) hypervalent iodoarene followed by functionalization thermal/photochemical conditions, (b) aryl-I bond in presence bases with/without organic catalysts promoters, (c) photoinduced presence/absence organophotocatalysts, (d) electrochemical direct/indirect electrolysis mediated organocatalysts mediators acting as electron shuttles, (e) electrophotochemical redox-active organocatalysts. These modes result exhibiting diverse reactivity formal cations/radicals/anions aryne precursors. coupling these reactive intermediates with leads to facile selective formation C-C C-heteroatom bonds. ecofriendly, inexpensive, functional group-tolerant offer alternatives transition metal-based catalysis.
Язык: Английский
Процитировано
0
Organic Letters, Год журнала: 2025, Номер unknown
Опубликована: Март 13, 2025
A visible-light-mediated photoredox catalysis for β-C(sp3)–H alkylation of 1-(o-iodoaryl)alkan-1-ones with alkenes via 1,5-hydrogen atom transfer and alkene alkylarylation to produce diverse β-alkyl arylalkanones containing a quaternary carbon center is presented. This method applicable wide range activated alkenes. Mechanistic studies suggest that the reaction involves radical process.
Язык: Английский
Процитировано
0
Chinese Journal of Chemistry, Год журнала: 2023, Номер 42(6), С. 585 - 591
Опубликована: Ноя. 2, 2023
Comprehensive Summary A straightforward electrochemical reduction of benzo[ b ]thiophene 1,1‐dioxides with HFIP as the hydrogen donor has been reported in an undivided cell under metal‐free conditions. Moreover, tolerance various functional groups and scaled‐up experiments showed practicability potential applications this methodology.
Язык: Английский
Процитировано
9
Organic Letters, Год журнала: 2024, Номер 26(29), С. 6114 - 6119
Опубликована: Июль 5, 2024
Difunctionalization of alkynes has gained a lot interest in current organic chemistry. Herein, we developed an electrophotocatalytic multicomponent cascade reaction and indoles with sulfinic acid sodium salts using elemental tellurium as the source. Using synergistic anodic oxidation visible-light irradiation, various β-(telluro)vinyl sulfones have been prepared. This strategy features mild conditions, excellent substrate scope, readily available starting materials, great functional group tolerance.
Язык: Английский
Процитировано
3
Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(15), С. 4182 - 4186
Опубликована: Янв. 1, 2024
In this paper, we developed an electro-reductive aryl-to-alkyl radical relay arylation reaction of a remote C(sp 3 )–H bond via 1,5-HAT process. This protocol features mild conditions, simple operation, and broad substrate scope.
Язык: Английский
Процитировано
2