Five-membered ring systems with O and N atoms DOI
Franca M. Cordero, Donatella Giomi, Fabrizio Machetti

и другие.

Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 275 - 308

Опубликована: Янв. 1, 2024

Язык: Английский

Copper nitrate-enabled ring expansion reaction of cyclopropanes: a direct approach to 3-cyano-isoxazoline N-oxides DOI
Yong Deng,

Zhenkun Yang,

Yanze Li

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(5), С. 1404 - 1411

Опубликована: Янв. 1, 2024

A novel copper nitrate-enabled ring expansion reaction of cyclopropanes with an unprecedented nitro and cyano group exchange process was reported, to afford pharmacologically interesting 3-cyano-isoxazoline N -oxides.

Язык: Английский

Процитировано

2
Copper‐Mediated Selective Multiple Inert Chemical Bonds Cleavage for Cyanation of Indoles via Tandem Carbon and Nitrogen Atom Transfer DOI
Shimin Xie, Fangfang Cai,

Lixin Liu

и другие.

Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(19), С. 2299 - 2304

Опубликована: Май 22, 2024

Comprehensive Summary The activation of inert chemical bonds is an exciting area research in chemistry because it enables the direct utilization readily available starting materials and promotes atom‐ step‐economic synthesis. Undoubtedly, selectively activating transforming multiple even more intriguing demanding task synthetic chemistry. However, due to its inherent complexity extreme challenges, this endeavour rarely accomplished. We report a copper‐mediated complete cleavage selective transformation three easily feedstocks, i.e ., sp 2 C—H bond indoles, 3 one C—N methyl carbon atom TMEDA, C≡N triple CH CN. This reaction proceeds via tandem nitrogen transfer, allows for efficient cyanation presenting simple alternative synthesizing 3‐cyanoindoles.

Язык: Английский

Процитировано

1
Rongalite/Iodine-Mediated C(sp3)–H Bond Oximation and Thiomethylation Reaction of Methyl Ketones Using Copper Nitrate as the [NO] Reagent: Synthesis of Thiohydroximic Acids DOI
Miao Wang, Huiying Ren,

Xiao-Yu Pu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(37), С. 7623 - 7627

Опубликована: Янв. 1, 2024

In this work, a highly efficient rongalite/iodine-mediated oxime formation reaction for the preparation of thiohydroximic acids from methyl ketones by employing copper nitrate as [NO] reagent has been developed. Notably, participated both catalyst and mild oximation in transformation. This is facile, with broad substrate scope, especially fused ring skeleton substrates, heterocyclic acetyl-substituted natural products. Mechanistic studies revealed that might be converted into NO

Язык: Английский

Процитировано

1
1,3-Difunctionalization of Donor–Acceptor Cyclopropanes Enabled by Copper Nitrate: A Direct Approach to γ-Halonitrates DOI

Ruoxin Huang,

Mingchun Gao,

Zhenkun Yang

и другие.

Organic Letters, Год журнала: 2024, Номер 26(45), С. 9659 - 9664

Опубликована: Окт. 31, 2024

1,3-Difunctionalization of donor–acceptor cyclopropanes with copper nitrate and N-halosuccinimide was developed to efficiently afford γ-halonitrates. The pivotal factor this protocol lies in the dual role as a Lewis acid an ideal nitrooxy source. given approach features easy handling, good functional group compatibility, wide substrate scope. Furthermore, various transformations obtained γ-chloronitrates underscore remarkable synthetic potential inherent method.

Язык: Английский

Процитировано

0
Five-membered ring systems with O and N atoms DOI
Franca M. Cordero, Donatella Giomi, Fabrizio Machetti

и другие.

Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 275 - 308

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0