Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 275 - 308
Опубликована: Янв. 1, 2024
Язык: Английский
Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 275 - 308
Опубликована: Янв. 1, 2024
Язык: Английский
Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(5), С. 1404 - 1411
Опубликована: Янв. 1, 2024
A novel copper nitrate-enabled ring expansion reaction of cyclopropanes with an unprecedented nitro and cyano group exchange process was reported, to afford pharmacologically interesting 3-cyano-isoxazoline N -oxides.
Язык: Английский
Процитировано
2Chinese Journal of Chemistry, Год журнала: 2024, Номер 42(19), С. 2299 - 2304
Опубликована: Май 22, 2024
Comprehensive Summary The activation of inert chemical bonds is an exciting area research in chemistry because it enables the direct utilization readily available starting materials and promotes atom‐ step‐economic synthesis. Undoubtedly, selectively activating transforming multiple even more intriguing demanding task synthetic chemistry. However, due to its inherent complexity extreme challenges, this endeavour rarely accomplished. We report a copper‐mediated complete cleavage selective transformation three easily feedstocks, i.e ., sp 2 C—H bond indoles, 3 one C—N methyl carbon atom TMEDA, C≡N triple CH CN. This reaction proceeds via tandem nitrogen transfer, allows for efficient cyanation presenting simple alternative synthesizing 3‐cyanoindoles.
Язык: Английский
Процитировано
1Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(37), С. 7623 - 7627
Опубликована: Янв. 1, 2024
In this work, a highly efficient rongalite/iodine-mediated oxime formation reaction for the preparation of thiohydroximic acids from methyl ketones by employing copper nitrate as [NO] reagent has been developed. Notably, participated both catalyst and mild oximation in transformation. This is facile, with broad substrate scope, especially fused ring skeleton substrates, heterocyclic acetyl-substituted natural products. Mechanistic studies revealed that might be converted into NO
Язык: Английский
Процитировано
1Organic Letters, Год журнала: 2024, Номер 26(45), С. 9659 - 9664
Опубликована: Окт. 31, 2024
1,3-Difunctionalization of donor–acceptor cyclopropanes with copper nitrate and N-halosuccinimide was developed to efficiently afford γ-halonitrates. The pivotal factor this protocol lies in the dual role as a Lewis acid an ideal nitrooxy source. given approach features easy handling, good functional group compatibility, wide substrate scope. Furthermore, various transformations obtained γ-chloronitrates underscore remarkable synthetic potential inherent method.
Язык: Английский
Процитировано
0Progress in heterocyclic chemistry, Год журнала: 2024, Номер unknown, С. 275 - 308
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0