Natural and Synthetic Peptides with Antifungal Activity

Future Medicinal Chemistry, Год журнала: 2016, Номер 8(12), С. 1413 - 1433

Опубликована: Авг. 1, 2016

In recent years, the increase of invasive fungal infections and emergence antifungal resistance stressed need for new drugs. Peptides have shown to be good candidates development alternative antimicrobial agents through high-throughput screening, subsequent optimization according a rational approach. This review presents brief overview on natural peptides different sources (animals, plants, micro-organisms), peptide fragments derived by proteolytic cleavage precursor physiological proteins (cryptides), synthetic unnatural derivatives. Antifungal are schematically reported based their structure, spectrum effects. Natural or modified derivatives may represent basis compounds active against infections.

Язык: Английский

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The Mechanisms of Action of Cationic Antimicrobial Peptides Refined by Novel Concepts from Biophysical Investigations

Advances in experimental medicine and biology, Год журнала: 2019, Номер unknown, С. 33 - 64

Опубликована: Янв. 1, 2019

Язык: Английский

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Facile fabrication of Tl₄HgI₆ nanostructures as novel antibacterial and antibiofilm agents and photocatalysts in the degradation of organic pollutants

Inorganic Chemistry Frontiers, Год журнала: 2021, Номер 8(10), С. 2442 - 2460

Опубликована: Янв. 1, 2021

Nano-Tl₄HgI₆ was fabricated via a co-precipitation route. It showed efficient antibacterial activity against Gram-negative and Gram-positive bacteria. Its photocatalytic indicated the highest degradation for RhB of around 78%.

Язык: Английский

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Advancements in antimicrobial nanoscale materials and self-assembling systems

Chemical Society Reviews, Год журнала: 2022, Номер 51(20), С. 8696 - 8755

Опубликована: Янв. 1, 2022

Antimicrobial resistance is directly responsible for more deaths per year than either HIV/AIDS or malaria and predicted to incur a cumulative societal financial burden of at least $100 trillion between 2014 2050.

Язык: Английский

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Antimicrobial Peptides and Small Molecules Targeting the Cell Membrane of Staphylococcus aureus

Microbiology and Molecular Biology Reviews, Год журнала: 2023, Номер 87(2)

Опубликована: Апрель 27, 2023

Clinical management of Staphylococcus aureus infections presents a challenge due to the high incidence, considerable virulence, and emergence drug resistance mechanisms.

Язык: Английский

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