Antimicrobial Peptides and Small Molecules Targeting the Cell Membrane of Staphylococcus aureus DOI

Narchonai Ganesan,

Biswajit Mishra,

Felix LewisOscar

et al.

Microbiology and Molecular Biology Reviews, Journal Year: 2023, Volume and Issue: 87(2)

Published: April 27, 2023

Clinical management of Staphylococcus aureus infections presents a challenge due to the high incidence, considerable virulence, and emergence drug resistance mechanisms.

Language: Английский

Natural and Synthetic Peptides with Antifungal Activity DOI
Tecla Ciociola, Laura Giovati, Stefania Conti

et al.

Future Medicinal Chemistry, Journal Year: 2016, Volume and Issue: 8(12), P. 1413 - 1433

Published: Aug. 1, 2016

In recent years, the increase of invasive fungal infections and emergence antifungal resistance stressed need for new drugs. Peptides have shown to be good candidates development alternative antimicrobial agents through high-throughput screening, subsequent optimization according a rational approach. This review presents brief overview on natural peptides different sources (animals, plants, micro-organisms), peptide fragments derived by proteolytic cleavage precursor physiological proteins (cryptides), synthetic unnatural derivatives. Antifungal are schematically reported based their structure, spectrum effects. Natural or modified derivatives may represent basis compounds active against infections.

Language: Английский

Citations

90
The Mechanisms of Action of Cationic Antimicrobial Peptides Refined by Novel Concepts from Biophysical Investigations DOI
Christopher Aisenbrey,

Arnaud Marquette,

Burkhard Bechinger

et al.

Advances in experimental medicine and biology, Journal Year: 2019, Volume and Issue: unknown, P. 33 - 64

Published: Jan. 1, 2019

Language: Английский

Citations

86
Facile fabrication of Tl4HgI6 nanostructures as novel antibacterial and antibiofilm agents and photocatalysts in the degradation of organic pollutants DOI
Maryam Karami, Mojgan Ghanbari, Hassan Abbas Alshamsi

et al.

Inorganic Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 8(10), P. 2442 - 2460

Published: Jan. 1, 2021

Nano-Tl4HgI6 was fabricated via a co-precipitation route. It showed efficient antibacterial activity against Gram-negative and Gram-positive bacteria. Its photocatalytic indicated the highest degradation for RhB of around 78%.

Language: Английский

Citations

59
Advancements in antimicrobial nanoscale materials and self-assembling systems DOI Creative Commons
Jack A. Doolan, George T. Williams, Kira L. F. Hilton

et al.

Chemical Society Reviews, Journal Year: 2022, Volume and Issue: 51(20), P. 8696 - 8755

Published: Jan. 1, 2022

Antimicrobial resistance is directly responsible for more deaths per year than either HIV/AIDS or malaria and predicted to incur a cumulative societal financial burden of at least $100 trillion between 2014 2050.

Language: Английский

Citations

50
Antimicrobial Peptides and Small Molecules Targeting the Cell Membrane of Staphylococcus aureus DOI

Narchonai Ganesan,

Biswajit Mishra,

Felix LewisOscar

et al.

Microbiology and Molecular Biology Reviews, Journal Year: 2023, Volume and Issue: 87(2)

Published: April 27, 2023

Clinical management of Staphylococcus aureus infections presents a challenge due to the high incidence, considerable virulence, and emergence drug resistance mechanisms.

Language: Английский

Citations

36