Advances in Neonatal Care,
Год журнала:
2022,
Номер
22(5), С. E169 - E181
Опубликована: Май 19, 2022
Background:
Black
mothers
and
their
very
low
birth-weight
infants
in
the
United
States
have
increased
risk
of
adverse
neonatal
maternal
health
outcomes
compared
with
White
infants.
Disparities
birth
associated
sociodemographic
factors
are
difficult
to
quantify
modify,
limiting
usefulness
assessing
intervention
effects.
Purpose:
To
test
hypotheses
that
(1)
biological
testosterone
cortisol
(2)
both
mental
healthy
behaviors
between
40
weeks'
gestational
age.
Methods:
We
used
a
descriptive,
longitudinal
design.
Eighty-eight
neonates
were
recruited
from
tertiary
medical
center
States.
Data
on
collected
records.
Maternal
questionnaires.
salivary
levels
measured
using
enzyme
immunoassays.
analyzed
primarily
general
linear
mixed
models.
Results:
High
and/or
younger
age,
less
education,
enrollment
federal
assistance
program,
being
unmarried,
Black,
poorer
health,
delayed
physical
growth.
Low
level
was
related
higher
depressive
symptoms.
had
fewer
than
mothers.
Implications
for
Practice
Research:
Findings
confirm
factors,
behaviors.
propose
concurrently
identify
develop
evaluate
ante-
postpartum
interventions.
Video
abstract
available
at
https://journals.na.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=59
Journal of Health Psychology,
Год журнала:
2021,
Номер
27(11), С. 2644 - 2667
Опубликована: Дек. 7, 2021
Pregnant
women
struggling
with
emotion
dysregulation
may
be
more
likely
to
engage
in
a
wide
range
of
health
risk
behaviors.
This
protocol
describes
study
on
intergenerational
transmission
from
the
third
trimester
pregnancy
18
months
postpartum.
Biobehavioral
markers
are
typically
measured
laboratory
settings
which
was
prohibited
by
many
universities
during
COVID-19
pandemic.
We
describe
how
(e.g.
maternal,
fetal,
and
infant
heart
rate
variability)
collected
remotely.
detail
data
collection
can
augmented
reach
diverse
populations
who
not
otherwise
participate
laboratory-based
research.
Background
Maternal
psychopathology
during
pregnancy
is
associated
with
negative
outcomes
in
offspring.
Increased
placental
transfer
of
maternal
cortisol
may
contribute
to
mediate
this
association.
Hair
concentrations
(HCCs)
appear
be
a
good
biomarker
long-term
prenatal
stress
exposure.
Little
known
about
the
associations
between
severe
and
perinatal
infant
HCCs.
Aims
We
assessed
HCCs
period
mother–infant
dyads
without
psychiatric
disorders.
Method
examined
group
differences
(
n
=
18)
subjected
disorders
versus
healthy
control
27).
correlation
mother
within
both
groups,
association
current
symptoms
patient
dyads.
Results
Median
(interquartile
range)
distribution
HCC
differed
patients
compared
mothers
U
468.5,
P
0.03).
infants
did
not
differ
from
250.0,
0.67).
Subsequently,
we
found
that
were
correlated
27,
r
0.55
(0.14),
0.003),
but
18,
0.082
(0.13),
0.746).
showed
positive
16,
0.63
(0.06),
0.008).
Conclusions
These
preliminary
findings
suggest
reflect
In
infants,
these
early
could
influence
lifetime
hypothalamic–pituitary–adrenal
axis
functioning,
which
might
increased
susceptibility
later
disease.
Research Square (Research Square),
Год журнала:
2023,
Номер
unknown
Опубликована: Сен. 21, 2023
Assessing
factors
that
influence
chronic
stress
biomarkers
like
hair
cortisol
concentrations
(HCCs)
in
pregnancy
is
critical
to
prevent
adverse
outcomes.
Thus,
we
aimed
identify
correlates
of
HCC
preconception
and
during
pregnancy.
2,581
pregnant
women
participated
the
study.
was
available
at
four
time
periods:
pre-pregnancy
(0-3
months
preconception,
n
=
1,023),
first
(1-12
weeks,
1,734),
second
(13-24
1,534),
third
(25-36
835)
trimesters.
assessed
using
liquid
chromatography
tandem
mass
spectrometry
(LC-MS/MS).
Sociodemographic,
pregnancy-
hair-related
characteristics,
measures
psychosocial
stress,
were
interrogated
as
potential
HCC.
Spearman
correlations,
paired
t-tests,
ANOVA
used
assess
differences
log-transformed
values
(logHCC)
across
maternal
characteristics.
Multivariable
linear
regressions
HCCs
after
adjusting
for
confounders.
Mean
logHCC
increased
prenatal
periods
(P
<
0.001).
In
multivariable
analyses,
BMI
consistently
associated
with
all
HCCs,
while
gestational
age,
economic
hardship,
dyeing,
depression,
showed
time-specific
associations
conclusion,
this
study
evidence
influencing
levels
before
The
most
consistent
association
seen
BMI.
Depression
also
concentrations.
Brazilian Journal of Health Review,
Год журнала:
2022,
Номер
5(2), С. 7027 - 7043
Опубликована: Апрель 20, 2022
O
estresse
materno
possui
um
impacto
significativo
no
desenvolvimento
fetal.
Objetivou-se
explorar
o
do
fetal
e
pós-natal.
Trata-se
de
uma
revisão
integrativa
da
literatura,
com
artigos
completos
disponíveis
na
base
eletrônica
Pubmed,
entre
os
anos
2013
a
2021,
nos
idiomas
português
inglês
uso
das
palavras-chave:
Estresse
Psicológico;
Gravidez;
Desenvolvimento
Fetal;
Relações
Materno-Fetais.
Foram
consultados
21
que
possibilitaram
atender
objetivo
desse
estudo,
todos
idioma
inglês.
Resultou
durante
gestação
pode
resultar
em
alterações
fenótipo
fisiologia
organismo.
nível
elevado
cortisol
foi
fator
mais
citado
como
provável
causador
desenvolvimento.
Considera-se
identificação
gestantes
risco
pré-natal
possibilita
ações
prevenção
controle
período
gestacional.
São
necessários
estudos
pesquisas
avaliem
intervenção
para
redução
agravo.
BMC Pregnancy and Childbirth,
Год журнала:
2024,
Номер
24(1)
Опубликована: Сен. 17, 2024
Abstract
Background
Newborns
are
shaped
by
prenatal
maternal
experiences.
These
include
a
pregnant
person’s
physical
health,
prior
pregnancy
experiences,
emotion
regulation,
and
socially
determined
health
markers.
We
used
series
of
machine
learning
models
to
predict
markers
fetal
growth
development—specifically,
newborn
birthweight
head
circumference
(HC).
Methods
pre-registered
archival
data
analytic
approach.
consisted
characteristics
594
maternal-infant
dyads
in
the
western
U.S.
Participants
also
completed
measure
dysregulation.
In
total,
there
were
22
predictors
HC
birthweight.
regularized
regression
for
predictor
selection
linear
prediction,
followed
nonlinear
if
overfit.
Results
was
predicted
best
with
model
(ridge
regression).
Newborn
sex
(male),
number
living
children,
BMI
larger
HC,
whereas
preeclampsia,
preterm
births,
race/ethnicity
(Latina)
smaller
HC.
Birthweight
(support
vector
machine).
Occupational
prestige
(a
marker
similar
socioeconomic
status)
higher
birthweight,
(non-White
non-Latina)
lower
difficulty
emotional
clarity
had
effects.
Conclusions
variety
variables
associated
stressful
spanning
medical,
psychological,
social
stress.
findings
may
highlight
importance
viewing
across
multiple
dimensions.
Findings
suggest
that
assessing
difficulties
during
standard
obstetric
care
(in
U.S.)
help
identify
risk
adverse
outcomes.
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 13, 2024
Abstract
Importance
Peripartum
depression
(PeriPD)
is
a
prevalent
condition
with
serious,
long-term
consequences
for
mother
and
child.
Emotion
regulation
(ER)
increasingly
recognized
as
key
factor
maternal
mental
health
parenting.
However,
evidence
remains
limited
regarding
the
relation
of
ER
difficulties
depressive
symptoms
across
peripartum.
Objective
To
determine
whether
self-reported
in
antepartum
are
associated
at
multiple
peripartum
timepoints.
Secondary
:
Whether
PeriPD
trajectories
differ
on
difficulties.
Design,
Setting
Participants
Data
this
study
were
collected
from
January
2022
to
April
2024
through
Mom2B
cohort,
population-based,
prospective
Swedish
national
using
smartphone
app
data
collection.
The
cohort
includes
Swedish-speaking,
pregnant
women
over
18
years,
residing
Sweden,
who
downloaded
app.
Eligibility
sub-study
required
verification
pregnancy
delivery,
along
complete
background
information
(N
=
1414).
included
if
they
completed
Difficulties
Regulation
Scale-16
(DERS-16)
during
second
trimester
623).
Exposure
DERS-16
total
score
16-25
weeks
antepartum.
Outcomes
Measures
Depressive
assessed
Edinburgh
Postnatal
Depression
Scale
(EPDS)
seven
timepoints:
24-34,
36-42
antepartum,
1-4,
6-13,
14-23,
24-35,
postpartum.
Multiple
linear
regression
models
examined
scores
exposure,
EPDS
outcomes,
adjusting
potential
confounders.
Comparison
between
ANOVA.
Results
623
women,
aged
19-44,
included.
strongly
up
14-23
postpartum,
even
after
confounders
(all
coefficients
.06
-
.23,
all
95%
CIs
.00
.26,
p
-values
<
.05).
134
participants
classified
into
specific
trajectory.
differed
(
F
(4,129)
26.68,
.001,
ηp
2
.45),
higher
early
late
postpartum-onset
compared
healthy
group
.017
.018,
respectively).
Conclusion
Relevance
present
robust
vulnerability
marker
symptoms,
particularly
progression
postpartum
depression.
may
aid
detection
risks,
while
enhancing
offers
promising
intervention
approach.
Further
research
needed
evaluate
DERS-16’s
clinical
utility
optimize
ER-centered
interventions
at-risk
trajectories.
Keypoints
Question
.
Are
emotion
timepoints?
Findings
In
population-based
study,
significantly
six
months
Meaning
study’s
findings
suggest
that
peripartum,
especially
provide
an
opportunity
approaches
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 14, 2024
Abstract
Pregnancy
is
a
psycho-neuro-endocrinological
transition
phase
in
which
plethora
of
hormone
levels
rise
substantially,
modulating
socioemotional
functions,
brain
structures,
and
networks
thus
presenting
window
vulnerability
for
mental
health.
A
transdiagnostic
factor
psychopathology
emotion
regulation,
influenced
by
sex
hormones,
such
as
estradiol
(E2),
across
the
menstrual
cycle
on
behavioral
neural
level.
Whether
this
also
case
antepartum
period
remains
unknown.
For
first
time,
regulation
were
investigated
healthy
primiparous
pregnant
females
with
extremely
high
E2
during
second
trimester
(N
=
15)
using
functional
magnetic
resonance
imaging
(fMRI)
paradigm.
Results
compared
naturally-cycling
(after
E2-administration,
N
16)
low
(early
follicular
phase,
16).
Although
reported
lowest
trait
use
cognitive
reappraisal,
all
successfully
regulated
their
emotions
applying
reappraisal
scanner.
On
level,
had
increased
activity
left
middle
frontal
gyrus
downregulation
negative
emotions.
Pregnant
showed
no
significant
differences
connectivity
(psychophysiological
interaction,
resting-state)
related
to
nonpregnant
group.
However,
group
emerged
amygdala
activation.
In
females,
predicted
reduced
success
was
positively
associated
depression
scores.
This
fMRI
study
pregnancy
indicates
that
scores
are
reflected
heightened
already
observable
period.
Thus,
through
its
association
success,
suggests
risk
marker
peripartum
Future
research
needs
investigate
postpartum
women
further
understand
pregnancy-related
changes
associations
mood,
emotional
functions.
Eventually,
will
allow
enhanced
identification,
prevention,
treatment
peri-
ill-health.
Advances in Neonatal Care,
Год журнала:
2022,
Номер
22(5), С. E169 - E181
Опубликована: Май 19, 2022
Background:
Black
mothers
and
their
very
low
birth-weight
infants
in
the
United
States
have
increased
risk
of
adverse
neonatal
maternal
health
outcomes
compared
with
White
infants.
Disparities
birth
associated
sociodemographic
factors
are
difficult
to
quantify
modify,
limiting
usefulness
assessing
intervention
effects.
Purpose:
To
test
hypotheses
that
(1)
biological
testosterone
cortisol
(2)
both
mental
healthy
behaviors
between
40
weeks'
gestational
age.
Methods:
We
used
a
descriptive,
longitudinal
design.
Eighty-eight
neonates
were
recruited
from
tertiary
medical
center
States.
Data
on
collected
records.
Maternal
questionnaires.
salivary
levels
measured
using
enzyme
immunoassays.
analyzed
primarily
general
linear
mixed
models.
Results:
High
and/or
younger
age,
less
education,
enrollment
federal
assistance
program,
being
unmarried,
Black,
poorer
health,
delayed
physical
growth.
Low
level
was
related
higher
depressive
symptoms.
had
fewer
than
mothers.
Implications
for
Practice
Research:
Findings
confirm
factors,
behaviors.
propose
concurrently
identify
develop
evaluate
ante-
postpartum
interventions.
Video
abstract
available
at
https://journals.na.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=59
