The Association between the Type and Level of Physical Activity and Metabolic Syndrome in Korean Adults Aged 40 Years and over: Results from the Eighth Korea National Health and Nutrition Examination Survey (2019–2021) DOI Open Access
Namkuk Son

The Korean Journal of Sports Medicine, Год журнала: 2024, Номер 42(2), С. 145 - 153

Опубликована: Май 30, 2024

Purpose:The purpose of this study was to elucidate the association between type and level physical activity metabolic syndrome (MetS) in Korean adults aged 40 years over.Methods: A total 11,848 over from eighth Korea National Health Nutrition Examination Survey (2019-2021) were analyzed.The participants classified into four groups according ('combined,' 'aerobic only,' 'resistance 'insufficiently active').MetS risk factors analyzed diagnostic criteria Society Cardiometabolic Syndrome.Complex samples logistic regression used estimate odds ratio (OR) 95% confidence interval (CI) relationship MetS after adjusting covariates.Results: Compared active' group, 'combined' group had a 28% lower (OR, 0.72; CI, 0.62-0.83), only' 19% 0.81; 0.72-0.92),and 40% 0.60; 0.50-0.72).The showed significantly for except 'high fasting glucose,' 'abdominal obesity' 'a low high-density lipoprotein cholesterol.'Conclusion: The results negative MetS.

Язык: Английский

Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments DOI Creative Commons
Ever Espino‐Gonzalez, Emilie Dalbram, Rémi Mounier

и другие.

Cell Metabolism, Год журнала: 2024, Номер 36(6), С. 1204 - 1236

Опубликована: Март 14, 2024

Diabetes represents a major public health concern with considerable impact on human life and healthcare expenditures. It is now well established that diabetes characterized by severe skeletal muscle pathology limits functional capacity quality of life. Increasing evidence indicates also one the most prevalent disorders impaired regeneration, yet underlying mechanisms therapeutic treatments remain poorly established. In this review, we describe cellular molecular alterations currently known to occur during regeneration in people animal models diabetes, including its associated comorbidities, e.g., obesity, hyperinsulinemia, insulin resistance. We role myogenic non-myogenic cell types conditions or without diabetes. Therapies for gaps our knowledge are discussed, while proposing future directions field.

Язык: Английский

Процитировано

26

Sarcopenia and Insulin Resistance Collective Effect on Atrial Fibrillation Risk: A Non‐Diabetic Elderly Cohort Study DOI Creative Commons
Weike Liu, Xin Wang, Yuqi Guo

и другие.

Journal of Cachexia Sarcopenia and Muscle, Год журнала: 2025, Номер 16(1)

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

2

Increased visceral fat area to skeletal muscle mass ratio is positively associated with the risk of metabolic dysfunction-associated steatotic liver disease in a Chinese population DOI Creative Commons

Chenbing Liu,

Nan Li, Di Sheng

и другие.

Lipids in Health and Disease, Год журнала: 2024, Номер 23(1)

Опубликована: Апрель 14, 2024

Abstract Background The diagnosis and comprehension of nonalcoholic fatty liver disease (NAFLD), recently redefined as metabolic dysfunction-associated steatotic (MASLD) are gaining a better understanding. In this study, we examined the association between visceral fat area skeletal muscle mass ratio (VSR) prevalence MASLD in Chinese population. Methods A cross-sectional study was conducted involving 10,916 individuals who underwent bioelectrical impedance analysis, along with anthropometric biochemical measurements, from January 2022 to June 2023. According VSR distribution, sex-specific quartiles within population were defined. Linear trend tests performed for categorized variables. Logistic regression models estimate odds 95% confidence intervals distribution stratified by sex. Results 37.94% overall (56.34% male), it gradually increased higher levels both genders ( P < 0.001). analysis demonstrated significant after adjusting confounders. (95% interval) MASLD, comparing lowest highest quartile, 3.159 (2.671, 3.736) men 2.230 (1.764, 2.819) women (all Restricted cubic splines also indicated non-linear relationships prevalence. Conclusions is positively associated population, notably risk increases compared women.

Язык: Английский

Процитировано

8

Higher triglyceride-glucose index and triglyceride glucose-body mass index protect against sarcopenia in Chinese middle-aged and older non-diabetic women: a cross-sectional study DOI Creative Commons
Min Li, Ying Liu, Lei Gao

и другие.

Frontiers in Public Health, Год журнала: 2025, Номер 12

Опубликована: Янв. 7, 2025

Sarcopenia, an age-related complication, constitutes a major public health problem given the aging of population. However, it is frequently overlooked and undertreated in mainstream practice. The study aimed to investigate correlations between triglyceride-glucose (TyG) index TyG-body mass (BMI) sarcopenia non-diabetic middle-aged older women whether they would be helpful indicators sarcopenia. This cross-sectional was conducted Department Endocrinology, Hebei Medical University Third Hospital. prospectively enrolled 460 postmenopausal aged ≥50 years. As TyG TyG-BMI increased, prevalence decreased. In multivariate analysis, were inversely associated with (OR: 0.492; 95% CI: 0.256-0.944 OR: 0.948; 0.934-0.962). Women fourth quartiles showed decreased OR 0.009 (95% 0.001-0.072) for respect first after adjusting confounding factors. area under curve (AUC) diagnosis 0.598 0.529-0.666), while AUC 0.858 0.816-0.899). Higher protected against females. Moreover, reliable cost-efficient biomarker predict

Язык: Английский

Процитировано

1

Role of Inflammatory Biomarkers in Mediating Causal Effect of Life Course Body Composition on Hypertension DOI
Liwan Fu, Yan Li, Hong Cheng

и другие.

Hypertension, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

BACKGROUND: The mediating role of inflammatory biomarkers in the causal relationship between body composition and hypertension remains unclear requires further investigation. METHODS: This study used a combination retrospective observational analysis Mendelian randomization approaches. Observational data were derived from 4717 Chinese children adolescents aged 6 to 18 years who underwent dual-energy X-ray absorptiometry assess composition. analyses utilized summary statistics large-scale sets, including UK Biobank, deCODE2021, International Consortium Blood Pressure, FinnGen, other consortia. included leptin, insulin, adiponectin, osteocalcin, FGF23 (fibroblast growth factor 23), PTH (parathyroid hormone). RESULTS: revealed that increased fat mass positively influenced diastolic blood pressure through while fat-free had an inverse effect. Insulin mediated association systolic pressure, hypertension, with additional indirect effects observed for (all P <0.05). demonstrated childhood index by insulin (indirect effect: odds ratio, 0.87 [95% CI, 0.78–0.97]) adiponectin (odds 1.13 1.04–1.23]). Adiponectin 0.81 0.71–0.93]) 1.30 1.11–1.51]) on hypertension. Leptin, also CONCLUSIONS: These findings indicate influences distinct biomarkers. Targeting may provide tailored strategies managing

Язык: Английский

Процитировано

1

Association between the oxidative balance score and low muscle mass in middle-aged US adults DOI Creative Commons
Kun Chen, Qiang Yin,

Jiangan Guan

и другие.

Frontiers in Nutrition, Год журнала: 2024, Номер 11

Опубликована: Апрель 5, 2024

Background Oxidative Balance Score (OBS) is a tool for assessing the oxidative stress-related exposures of diet and lifestyle. The study aimed to investigate association between OBS low muscle mass. Methods Overall, 6,307 individuals over age 18 were assessed using data from 2011 2018 National Health Nutrition Examination Survey (NHANES). Weighted logistic regression models used, together with adjusted models. Results There was negative relationship mass [odds ratio (OR): 0.96, 95% confidence interval (CI): 0.94–0.97, p &lt; 0.0001] first level as reference. values (all CI) 0.745 (0.527–1.054) second level, 0.650 (0.456–0.927) third 0.326 (0.206–0.514) fourth (P trend &lt;0.0001). Independent links found lifestyle factors. A restricted cubic spline model indicated non-linear risk non-linearity&lt;0.05). In addition, inflection points nonlinear curves 20. Conclusion be significantly negatively correlated. By modulating balance, healthy antioxidant rich could preventive strategy

Язык: Английский

Процитировано

6

The triglyceride glucose related index is an indicator of Sarcopenia DOI Creative Commons
Zihao Zhang, Xin Chen, Na Jiang

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Окт. 15, 2024

The triglyceride glucose (TyG) related index, a metric used to evaluate assessing insulin resistance (IR), has received limited attention in its association with sarcopenia. Our study aims explore the predictive potential of TyG index for This utilized data from China Health and Retirement Longitudinal Study, nationally representative, community-based cohort study, including sample size 10,537 participants aged 45 years older. Associations between sacopenia was explored using multivariate logistic regression. Analysis value sarcopenia receiver-operating characteristic curve (ROC). We evaluated correlation risk Cox proportional hazards models. Additionally, we restricted cubic spline (RCS) regression analyses connections TyG-related Logistic analysis showed an (OR 0.961[0.955,0.968], P < 0.001), TyG-body mass (TyG-BMI) 0.872[0.867,0.878], TyG- waist circumference (TyG-WC) 0.896[0.890,0.902], 0.001) results ROC indicated that area under values TyG, TyG-BMI, TyG-WC were 0.659, 0.903, 0.819, respectively. Compared those without sarcopenia, patients had 37.7% (HR 0.623[0.502,0.774], 4.8% 0.952[0.947,0.958], 0.4% 0.996[0.995,0.996], lower increasing TyG-WC, RCS show nonlinear relationship TyG-BMI (P observed demonstrating strong capability

Язык: Английский

Процитировано

5

Low muscle mass index is associated with type 2 diabetes risk in a Latin-American population: a cross-sectional study DOI Creative Commons
Rosario Suárez,

Celina Andrade,

Estefanía Bautista-Valarezo

и другие.

Frontiers in Nutrition, Год журнала: 2024, Номер 11

Опубликована: Июль 30, 2024

Diabetes mellitus is a growing disease with severe complications. Various scores predict the risk of developing this pathology. The amount muscle mass associated insulin resistance, yet there no established evidence linking diabetes risk. This work aims to study that relationship.

Язык: Английский

Процитировано

4

Association of triglyceride-glucose index with sarcopenia: NHANES 2011–2014 DOI Creative Commons

Wei Xue,

Dandan Liu

Frontiers in Endocrinology, Год журнала: 2024, Номер 15

Опубликована: Сен. 23, 2024

A newly developed technique, the Triglyceride-glucose (TyG) index, supplies a more straightforward method to identify IR than HOMA-IR (Homeostasis Model Assessment of Insulin Resistance). Yet no methodical analysis has looked into link involving TyG index and low muscle mass (LMM), strength (LMS), sarcopenia within US. Thus, this study intended find any connection concerning LMM, LMS, sarcopenia.

Язык: Английский

Процитировано

4

Effect of life course body composition on lipids and coronary atherosclerosis mediated by inflammatory biomarkers DOI
Liwan Fu, Hong Cheng, Jingfan Xiong

и другие.

Free Radical Biology and Medicine, Год журнала: 2024, Номер 227, С. 157 - 165

Опубликована: Дек. 6, 2024

Язык: Английский

Процитировано

4