The Korean Journal of Sports Medicine,
Год журнала:
2024,
Номер
42(2), С. 145 - 153
Опубликована: Май 30, 2024
Purpose:The
purpose
of
this
study
was
to
elucidate
the
association
between
type
and
level
physical
activity
metabolic
syndrome
(MetS)
in
Korean
adults
aged
40
years
over.Methods:
A
total
11,848
over
from
eighth
Korea
National
Health
Nutrition
Examination
Survey
(2019-2021)
were
analyzed.The
participants
classified
into
four
groups
according
('combined,'
'aerobic
only,'
'resistance
'insufficiently
active').MetS
risk
factors
analyzed
diagnostic
criteria
Society
Cardiometabolic
Syndrome.Complex
samples
logistic
regression
used
estimate
odds
ratio
(OR)
95%
confidence
interval
(CI)
relationship
MetS
after
adjusting
covariates.Results:
Compared
active'
group,
'combined'
group
had
a
28%
lower
(OR,
0.72;
CI,
0.62-0.83),
only'
19%
0.81;
0.72-0.92),and
40%
0.60;
0.50-0.72).The
showed
significantly
for
except
'high
fasting
glucose,'
'abdominal
obesity'
'a
low
high-density
lipoprotein
cholesterol.'Conclusion:
The
results
negative
MetS.
Cell Metabolism,
Год журнала:
2024,
Номер
36(6), С. 1204 - 1236
Опубликована: Март 14, 2024
Diabetes
represents
a
major
public
health
concern
with
considerable
impact
on
human
life
and
healthcare
expenditures.
It
is
now
well
established
that
diabetes
characterized
by
severe
skeletal
muscle
pathology
limits
functional
capacity
quality
of
life.
Increasing
evidence
indicates
also
one
the
most
prevalent
disorders
impaired
regeneration,
yet
underlying
mechanisms
therapeutic
treatments
remain
poorly
established.
In
this
review,
we
describe
cellular
molecular
alterations
currently
known
to
occur
during
regeneration
in
people
animal
models
diabetes,
including
its
associated
comorbidities,
e.g.,
obesity,
hyperinsulinemia,
insulin
resistance.
We
role
myogenic
non-myogenic
cell
types
conditions
or
without
diabetes.
Therapies
for
gaps
our
knowledge
are
discussed,
while
proposing
future
directions
field.
Lipids in Health and Disease,
Год журнала:
2024,
Номер
23(1)
Опубликована: Апрель 14, 2024
Abstract
Background
The
diagnosis
and
comprehension
of
nonalcoholic
fatty
liver
disease
(NAFLD),
recently
redefined
as
metabolic
dysfunction-associated
steatotic
(MASLD)
are
gaining
a
better
understanding.
In
this
study,
we
examined
the
association
between
visceral
fat
area
skeletal
muscle
mass
ratio
(VSR)
prevalence
MASLD
in
Chinese
population.
Methods
A
cross-sectional
study
was
conducted
involving
10,916
individuals
who
underwent
bioelectrical
impedance
analysis,
along
with
anthropometric
biochemical
measurements,
from
January
2022
to
June
2023.
According
VSR
distribution,
sex-specific
quartiles
within
population
were
defined.
Linear
trend
tests
performed
for
categorized
variables.
Logistic
regression
models
estimate
odds
95%
confidence
intervals
distribution
stratified
by
sex.
Results
37.94%
overall
(56.34%
male),
it
gradually
increased
higher
levels
both
genders
(
P
<
0.001).
analysis
demonstrated
significant
after
adjusting
confounders.
(95%
interval)
MASLD,
comparing
lowest
highest
quartile,
3.159
(2.671,
3.736)
men
2.230
(1.764,
2.819)
women
(all
Restricted
cubic
splines
also
indicated
non-linear
relationships
prevalence.
Conclusions
is
positively
associated
population,
notably
risk
increases
compared
women.
Frontiers in Public Health,
Год журнала:
2025,
Номер
12
Опубликована: Янв. 7, 2025
Sarcopenia,
an
age-related
complication,
constitutes
a
major
public
health
problem
given
the
aging
of
population.
However,
it
is
frequently
overlooked
and
undertreated
in
mainstream
practice.
The
study
aimed
to
investigate
correlations
between
triglyceride-glucose
(TyG)
index
TyG-body
mass
(BMI)
sarcopenia
non-diabetic
middle-aged
older
women
whether
they
would
be
helpful
indicators
sarcopenia.
This
cross-sectional
was
conducted
Department
Endocrinology,
Hebei
Medical
University
Third
Hospital.
prospectively
enrolled
460
postmenopausal
aged
≥50
years.
As
TyG
TyG-BMI
increased,
prevalence
decreased.
In
multivariate
analysis,
were
inversely
associated
with
(OR:
0.492;
95%
CI:
0.256-0.944
OR:
0.948;
0.934-0.962).
Women
fourth
quartiles
showed
decreased
OR
0.009
(95%
0.001-0.072)
for
respect
first
after
adjusting
confounding
factors.
area
under
curve
(AUC)
diagnosis
0.598
0.529-0.666),
while
AUC
0.858
0.816-0.899).
Higher
protected
against
females.
Moreover,
reliable
cost-efficient
biomarker
predict
BACKGROUND:
The
mediating
role
of
inflammatory
biomarkers
in
the
causal
relationship
between
body
composition
and
hypertension
remains
unclear
requires
further
investigation.
METHODS:
This
study
used
a
combination
retrospective
observational
analysis
Mendelian
randomization
approaches.
Observational
data
were
derived
from
4717
Chinese
children
adolescents
aged
6
to
18
years
who
underwent
dual-energy
X-ray
absorptiometry
assess
composition.
analyses
utilized
summary
statistics
large-scale
sets,
including
UK
Biobank,
deCODE2021,
International
Consortium
Blood
Pressure,
FinnGen,
other
consortia.
included
leptin,
insulin,
adiponectin,
osteocalcin,
FGF23
(fibroblast
growth
factor
23),
PTH
(parathyroid
hormone).
RESULTS:
revealed
that
increased
fat
mass
positively
influenced
diastolic
blood
pressure
through
while
fat-free
had
an
inverse
effect.
Insulin
mediated
association
systolic
pressure,
hypertension,
with
additional
indirect
effects
observed
for
(all
P
<0.05).
demonstrated
childhood
index
by
insulin
(indirect
effect:
odds
ratio,
0.87
[95%
CI,
0.78–0.97])
adiponectin
(odds
1.13
1.04–1.23]).
Adiponectin
0.81
0.71–0.93])
1.30
1.11–1.51])
on
hypertension.
Leptin,
also
CONCLUSIONS:
These
findings
indicate
influences
distinct
biomarkers.
Targeting
may
provide
tailored
strategies
managing
Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Апрель 5, 2024
Background
Oxidative
Balance
Score
(OBS)
is
a
tool
for
assessing
the
oxidative
stress-related
exposures
of
diet
and
lifestyle.
The
study
aimed
to
investigate
association
between
OBS
low
muscle
mass.
Methods
Overall,
6,307
individuals
over
age
18
were
assessed
using
data
from
2011
2018
National
Health
Nutrition
Examination
Survey
(NHANES).
Weighted
logistic
regression
models
used,
together
with
adjusted
models.
Results
There
was
negative
relationship
mass
[odds
ratio
(OR):
0.96,
95%
confidence
interval
(CI):
0.94–0.97,
p
<
0.0001]
first
level
as
reference.
values
(all
CI)
0.745
(0.527–1.054)
second
level,
0.650
(0.456–0.927)
third
0.326
(0.206–0.514)
fourth
(P
trend
<0.0001).
Independent
links
found
lifestyle
factors.
A
restricted
cubic
spline
model
indicated
non-linear
risk
non-linearity<0.05).
In
addition,
inflection
points
nonlinear
curves
20.
Conclusion
be
significantly
negatively
correlated.
By
modulating
balance,
healthy
antioxidant
rich
could
preventive
strategy
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Окт. 15, 2024
The
triglyceride
glucose
(TyG)
related
index,
a
metric
used
to
evaluate
assessing
insulin
resistance
(IR),
has
received
limited
attention
in
its
association
with
sarcopenia.
Our
study
aims
explore
the
predictive
potential
of
TyG
index
for
This
utilized
data
from
China
Health
and
Retirement
Longitudinal
Study,
nationally
representative,
community-based
cohort
study,
including
sample
size
10,537
participants
aged
45
years
older.
Associations
between
sacopenia
was
explored
using
multivariate
logistic
regression.
Analysis
value
sarcopenia
receiver-operating
characteristic
curve
(ROC).
We
evaluated
correlation
risk
Cox
proportional
hazards
models.
Additionally,
we
restricted
cubic
spline
(RCS)
regression
analyses
connections
TyG-related
Logistic
analysis
showed
an
(OR
0.961[0.955,0.968],
P
<
0.001),
TyG-body
mass
(TyG-BMI)
0.872[0.867,0.878],
TyG-
waist
circumference
(TyG-WC)
0.896[0.890,0.902],
0.001)
results
ROC
indicated
that
area
under
values
TyG,
TyG-BMI,
TyG-WC
were
0.659,
0.903,
0.819,
respectively.
Compared
those
without
sarcopenia,
patients
had
37.7%
(HR
0.623[0.502,0.774],
4.8%
0.952[0.947,0.958],
0.4%
0.996[0.995,0.996],
lower
increasing
TyG-WC,
RCS
show
nonlinear
relationship
TyG-BMI
(P
observed
demonstrating
strong
capability
Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Июль 30, 2024
Diabetes
mellitus
is
a
growing
disease
with
severe
complications.
Various
scores
predict
the
risk
of
developing
this
pathology.
The
amount
muscle
mass
associated
insulin
resistance,
yet
there
no
established
evidence
linking
diabetes
risk.
This
work
aims
to
study
that
relationship.
Frontiers in Endocrinology,
Год журнала:
2024,
Номер
15
Опубликована: Сен. 23, 2024
A
newly
developed
technique,
the
Triglyceride-glucose
(TyG)
index,
supplies
a
more
straightforward
method
to
identify
IR
than
HOMA-IR
(Homeostasis
Model
Assessment
of
Insulin
Resistance).
Yet
no
methodical
analysis
has
looked
into
link
involving
TyG
index
and
low
muscle
mass
(LMM),
strength
(LMS),
sarcopenia
within
US.
Thus,
this
study
intended
find
any
connection
concerning
LMM,
LMS,
sarcopenia.
