Chemistry - An Asian Journal,
Год журнала:
2022,
Номер
17(8)
Опубликована: Март 16, 2022
A
metal-
and
catalyst-free
photo-promoted
cyclization
of
properly
substituted
vinyl
selenides
was
developed
using
UVA
irradiation.
total
eighteen
new
C3-unsubstituted
2-selanyl
benzochalcogenophenes
(benzofurans,
benzothiophenes
benzoselenophenes)
were
prepared
in
30-86%
yield
after
irradiation
with
at
room
temperature.
The
usefulness
the
title
compounds
demonstrated
easy
functionalization
remaining
free
C-H
bond
to
form
C-Se
C-Br
bonds
by
simple
procedures.
Furthermore,
reaction
can
be
performed
under
natural
sunlight
solvent
is
easily
reused
further
several
subsequent
runs.
Chemical Reviews,
Год журнала:
2021,
Номер
122(2), С. 2017 - 2291
Опубликована: Ноя. 23, 2021
We
present
here
a
review
of
the
photochemical
and
electrochemical
applications
multi-site
proton-coupled
electron
transfer
(MS-PCET)
in
organic
synthesis.
MS-PCETs
are
redox
mechanisms
which
both
an
proton
exchanged
together,
often
concerted
elementary
step.
As
such,
MS-PCET
can
function
as
non-classical
mechanism
for
homolytic
bond
activation,
providing
opportunities
to
generate
synthetically
useful
free
radical
intermediates
directly
from
wide
variety
common
functional
groups.
introduction
practitioner’s
guide
reaction
design,
with
emphasis
on
unique
energetic
selectivity
features
that
characteristic
this
class.
then
chapters
oxidative
N–H,
O–H,
S–H,
C–H
homolysis
methods,
generation
corresponding
neutral
species.
Then,
reductive
PCET
activations
involving
carbonyl,
imine,
other
X═Y
π-systems,
heteroarenes,
where
ketyl,
α-amino,
heteroarene-derived
radicals
be
generated.
Finally,
we
asymmetric
catalysis
materials
device
applications.
Within
each
chapter,
subdivide
by
group
undergoing
homolysis,
thereafter
type
transformation
being
promoted.
Methods
published
prior
end
December
2020
presented.
The Journal of Organic Chemistry,
Год журнала:
2021,
Номер
86(14), С. 9658 - 9669
Опубликована: Июль 2, 2021
A
visible
light
(white
light-emitting
diode/direct
sunlight)-driven
photochemical
synthesis
of
a
new
series
biologically
interesting
3-(alkyl/benzylthio)-4-hydroxy-2H-chromen-2-ones
has
been
achieved
through
cross-dehydrogenative
C3-H
sulfenylation
4-hydroxycoumarins
with
thiols
at
ambient
temperature
in
the
presence
rose
bengal
acetonitrile
under
an
oxygen
atmosphere.
The
notable
features
this
newly
developed
method
are
mild
reaction
conditions,
energy
efficiency,
metal-free
synthesis,
good
to
excellent
yields,
use
low-cost
materials,
and
eco-friendliness.
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(20), С. 3413 - 3431
Опубликована: Сен. 12, 2023
Abstract
Due
their
multifaced
applications,
the
access
to
organosulfur
derivatives
in
an
efficient
and
economical
way
is
a
challenge
organic
synthesis.
In
this
context
photochemistry
photocatalysis
play
crucial
role
development
of
innovative
(and
selective)
Carbon‐Sulphur
bond
formation
processes.
The
present
review
aims
collect
most
recent
strategies
achieve
target
under
visible
light
driven
conditions.
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(11), С. 1714 - 1755
Опубликована: Апрель 12, 2023
Abstract
In
the
last
decade,
free
radicals
have
found
a
wide
application
in
functionalization
of
unsaturated
compounds,
such
as
alkenes,
alkynes,
and
arenes,
via
free‐radical
addition
to
carbon‐carbon
π‐bonds.
these
processes,
intermolecular
attack
on
aromatic
substrates
represents
challenge
due
relatively
high
resistance
π‐system
reactions
comparison
alkene
C=C
bonds.
The
heterocycles
is
especially
interesting
diversity
their
structures
chemical
properties
well
importance
for
medicinal
chemistry,
agrochemistry,
materials
science.
Addition
C‐centered
widely
known
Minisci‐type
well‐reviewed.
this
paper,
we
summarized
main
achievements
less
explored
group
processes:
by
heteroatom‐centered
(O‐,
N‐,
S‐/Se‐,
P‐radicals)
with
emphasis
papers
published
after
2010.
Literature
analysis
revealed
strong
trend
towards
usage
electrochemistry
photoredox‐catalysis
generation
recent
years.
remaining
fundamental
problem
field
lack
experimental
support
proposed
mechanisms
frequent
existence
several
plausible
reaction
pathways.
progress
mechanistic
studies
can
significantly
improve
prediction
optimal
conditions
depending
structure.
The Journal of Organic Chemistry,
Год журнала:
2021,
Номер
86(22), С. 15973 - 15991
Опубликована: Июнь 29, 2021
Oxidation
potential-guided
electrochemical
radical–radical
cross-coupling
reactions
between
N-heteroarenes
and
sodium
sulfinates
have
been
established.
Thus,
simple
cyclic
voltammetry
measurement
of
substrates
predicts
the
likelihood
successful
coupling
reactions,
allowing
direct
synthetic
access
to
3-sulfonylated
imidazopyridines
indolizines.
The
developed
sulfonylated
boast
green
nature
that
are
oxidant-
metal-free.
Abstract
C−H
functionalized
indolizines
have
emerged
as
a
modern
sustainable
protocol,
it
offers
robust
applications
in
the
field
of
agriculture,
medicine
and
pharmaceutical
sciences.
In
recent
times,
number
effective
methods
for
C−C,
C−P
C−S
bond
formation
via
functionalization
been
established.
The
present
review
article
provides
thorough
assessment
developments
indolizines.
has
categorized
based
on
using
conventional
well
non‐conventional
methodologies.
Moreover,
reaction
mechanism
discussed
elaborated
form.
Chemical Communications,
Год журнала:
2023,
Номер
59(36), С. 5415 - 5418
Опубликована: Янв. 1, 2023
For
the
first
time,
we
report
transition
metal-free
electrochemical
site-selective
direct
C–H
sulfenylation/selenylation
of
chromone-fused
indolizine
compounds
(CFIs)
to
afford
corresponding
CFIs
thioethers
and
selenoethers
in
58–96%
yields.
Organic & Biomolecular Chemistry,
Год журнала:
2023,
Номер
22(4), С. 645 - 681
Опубликована: Дек. 23, 2023
Organochalcogen
compounds
are
prevalent
in
numerous
natural
products,
pharmaceuticals,
agrochemicals,
polymers,
biological
molecules
and
synthetic
intermediates.
Direct
chalcogenation
of
C-H
bonds
has
evolved
as
a
step-
atom-economical
method
for
the
synthesis
chalcogen-bearing
compounds.
Nevertheless,
direct
severely
lags
behind
C-C,
C-N
C-O
bond
formations.
Moreover,
compared
with
monochalcogenation,
reports
selective
mono-/dichalcogenation
exclusive
dichalcogenation
relatively
scarce.
The
past
decade
witnessed
significant
advancements
various
C(sp
Chinese Journal of Organic Chemistry,
Год журнала:
2024,
Номер
44(2), С. 398 - 398
Опубликована: Янв. 1, 2024
The
structure
of
3-sulfenyl
indoles
widely
exists
in
many
drug
molecules
and
natural
product
molecules.Its
derivatives
have
extensive
biological
activities
such
as
antibacterial,
antiviral
anti-tumor,
are
also
important
intermediates
organic
synthesis
structural
units
synthesis.Therefore,
indole
compounds
great
application
value
the
field
medicine.The
research
its
method
has
become
one
current
hotspots.In
this
paper,
progress
recent
years
is
reviewed,
some
reaction
mechanisms
discussed.
