European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Март 26, 2024
Abstract
Herein
we
first
report
the
unprecedented
synthesis
of
tetrazene‐based
cobalt
complexes
using
unusual
coupling
amines
via
dehydrogenation.
These
were
employed
for
dehydrogenative
reactions
to
synthesize
N‐heterocycles
(quinoline,
and
quinazolinone).
Based
on
control
experiments
IR
identification
intermediates,
proposed
a
plausible
reaction
mechanism.
Synthesis
protocols
utilized
preparative
scale
biologically
active
molecule
(±)‐galipinine
synthesis.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(24), С. 16967 - 16977
Опубликована: Ноя. 29, 2023
We
demonstrate
an
efficient
and
sustainable
strategy
for
the
direct
synthesis
of
2,4-disubstituted
quinazolines
by
arene
Ru(II)benzhydrazone
complex
via
eco-friendly
sequential
acceptorless
dehydrogenative
coupling
2-aminobenzhydrol
derivatives
benzyl
alcohols
first
time.
The
new
ruthenium(II)
general
formula
[(η6-p-cymene)Ru(L1)Cl]
(L1-acenaphthenequinone
hydrazone)
has
been
synthesized
characterized
analytical,
spectroscopic,
single-crystal
X-ray
diffraction
techniques.
A
broad
spectrum
have
successfully
derived
(25
examples)
from
with
various
using
1
mol
%
catalyst
loading
in
presence
NH4OAc.
present
protocol
is
highly
selective
produces
a
maximum
yield
95%
under
mild
reaction
conditions.
different
intermediates
detected
through
control
experiments
such
as
aldehyde,
2-aminobenzophenone,
benzylidene(amino)phenylmethanone,
1,2-dihydroquinazoline
are
isolated
authenticated
NMR
study.
Gratifyingly,
simple
atom
economic
release
water
hydrogen
gas
only
byproducts.
gram-scale
2-(4-methoxyphenyl)-4-phenylquinazoline
illustrates
synthetic
utility
protocol.
Organic Chemistry Frontiers,
Год журнала:
2022,
Номер
10(1), С. 22 - 29
Опубликована: Ноя. 16, 2022
Divergent
deaminative
and
denitrative
C–N
cleavages
cascade
transformations
using
amines
nitroalkanes
have
been
developed
under
a
highly
effective
environmentally-friendly
catalytic
system
(RuCl
3
/TFE).
Applied Organometallic Chemistry,
Год журнала:
2023,
Номер
37(5)
Опубликована: Фев. 27, 2023
An
efficient
Pd(II)N^N^S
pincer
type
catalysts‐promoted
sustainable
construction
of
pharmaceutically
important
benzothiazole
derivatives
from
primary
alcohols
and
2‐aminothiophenol
via
acceptorless
dehydrogenative
coupling
(ADC)
method
has
been
described.
The
newly
synthesized
ligand
L
2
the
Pd(II)
complexes
in
addition
to
1
3
were
characterized
by
analytical
Fourier
transform
infrared
spectroscopy
(FT‐IR),
UV–visible
(UV–vis),
nuclear
magnetic
resonance
(NMR)
spectral
techniques.
Further,
ORTEP
views
established
a
single
crystal
XRD
study,
which
evidenced
coordination
thiosemicarbazone
ligands
disclose
square‐planar
geometry
around
ion.
present
homogeneous
catalytic
system
involves
synthesizing
range
benzothiazoles
C−S
C−N
bond
formation
with
excellent
yields
up
93%.
described
methodology
employs
sustainable,
highly
abundant,
inexpensive
alcohol
as
starting
material
using
mol%
catalyst
loading,
water
hydrogen
gas
are
only
by‐products.
Furthermore,
plausible
mechanism
involving
situ
aldehyde
dehydrogenation
proposed.
A
large‐scale
synthesis
2‐(4‐methoxyphenyl)benzo[d]thiazole
illustrates
synthetic
utility
protocol.
Catalysis Science & Technology,
Год журнала:
2023,
Номер
13(10), С. 3069 - 3083
Опубликована: Янв. 1, 2023
Heterogeneous
catalytic
oxidative
dehydrogenative
processes
for
N-heterocycles
are
presented,
which
enable
waste-minimized
(additive-,
oxidant-,
base-free),
efficient
cyclisations/couplings
via
transition
metal
oxide–Bi(
iii
)
cooperative
catalysis.
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Март 26, 2024
Abstract
Herein
we
first
report
the
unprecedented
synthesis
of
tetrazene‐based
cobalt
complexes
using
unusual
coupling
amines
via
dehydrogenation.
These
were
employed
for
dehydrogenative
reactions
to
synthesize
N‐heterocycles
(quinoline,
and
quinazolinone).
Based
on
control
experiments
IR
identification
intermediates,
proposed
a
plausible
reaction
mechanism.
Synthesis
protocols
utilized
preparative
scale
biologically
active
molecule
(±)‐galipinine
synthesis.