European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(19)
Опубликована: Апрель 12, 2024
Abstract A simple strategy to 3‐acylated quinoxalin‐2(1 H )‐ones via a photo‐induced cross‐dehydrogenative coupling of with commercially available aldehyde under metal free conditions without an external photocatalyst was developed. In this transformation, various were generated in high yields good functional‐group tolerance.
Язык: Английский
Chemistry - A European Journal, Год журнала: 2024, Номер 30(41)
Опубликована: Апрель 22, 2024
With both TEMPO and O
Язык: Английский
Процитировано
5
Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(33), С. 6799 - 6809
Опубликована: Янв. 1, 2024
A visible-light-induced tandem reaction involving quinoxalin-2(1
Язык: Английский
Процитировано
4
The Journal of Organic Chemistry, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 25, 2024
Herein, the first example of self-catalyzed sono-photoinduced carbon-carbon bond formation was described. Combining advantages phototriggered self-catalysis and ultrasonic catalysis, a wide range 3-arylquinoxalin-2(1
Язык: Английский
Процитировано
4
JACS Au, Год журнала: 2025, Номер unknown
Опубликована: Янв. 29, 2025
The N-heterocyclic carbene (NHC)-catalyzed umpolung of aldimines using quinoxalin-2-ones for intermolecular reactions is demonstrated. Specifically, NHC-catalyzed cross-coupling with isatins proceeds via the generation aza-Breslow intermediates by addition to C═N moiety quinoxalinones followed interception afford diverse oxindoles in moderate good yields and functional group compatibility. Moreover, detailed mechanistic studies involving isolation characterization imidoyl azoliums (oxidized form intermediates) are provided. Considering significance scaffolds bearing both quinoxalin-2-one oxindole moieties medicine natural products, synthesized molecules employing imine strategy likely find promising applications.
Язык: Английский
Процитировано
0
The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Фев. 24, 2025
Pd-catalyzed photochemical reductive alkylation of quinoxalin-2(1H)-ones and dibenzoxazepines with readily available alkyl bromides has been developed. The dependence oxidative chemoselectivity on the nature base was established. A variety primary, secondary, tertiary halides have successfully employed in this transformation, which features a wide substrate scope under mild reaction conditions is also applicable to dibenzoxazepines.
Язык: Английский
Процитировано
0
ChemistrySelect, Год журнала: 2025, Номер 10(12)
Опубликована: Март 1, 2025
Abstract In light of the extensive application fluoroalkyl‐containing molecules and functionalized quinoxalin‐2(1 H )‐ones in medicinal chemistry functional materials, visible‐light‐enabled C3‐H fluoroalkylation has garnered significant attention. this review, we provide a detailed overview latest advancements rapidly evolving research area. We cover utilization various fluoroalkyl sources under conditions photocatalyst or without photocatalyst, discuss pertinent reaction conditions, mechanisms, substrate scope. Our objective is to help more chemists comprehend challenges opportunities within field, thereby fostering its development.
Язык: Английский
Процитировано
0
RSC Advances, Год журнала: 2025, Номер 15(20), С. 16183 - 16186
Опубликована: Янв. 1, 2025
An efficient radical alkylative annulation/arylation of N -(arylsulfonyl)acrylamide with 4-alkyl-1,4-dihydropyridines (DHP) was developed for synthesizing all-carbon quaternary-centered β-alkyl amides.
Язык: Английский
Процитировано
0
European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(19)
Опубликована: Март 21, 2024
Abstract Herein, visible‐light‐induced metal‐free three‐component amidoheteroarylation of alkenes with quinoxalin‐2(1 H )‐ones and N‐sulfonylaminopyridinium salts is developed. This protocol involves a radical relay process in which the N‐centered radicals undergo chemoselective addition to form an alkyl that selectively combines heteroarenes, leading formation C−C C−N bonds one step under mild reaction conditions. The involved high efficiency selectivity, wide substrate scope, excellent functional‐group compatibility demonstrate practicability developed protocol.
Язык: Английский
Процитировано
3
The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(17), С. 12693 - 12700
Опубликована: Авг. 26, 2024
FeTiO3 has emerged as an interesting semiconductor photocatalyst in organic synthesis. We herein describe a visible-light-induced semiheterogeneous strategy for the synthesis of 3-(2-oxoethyl)indolin-2-ones with moderate to good yields and functional group compatibility using recyclable NHPI redox catalyst.
Язык: Английский
Процитировано
3
Advanced Synthesis & Catalysis, Год журнала: 2024, Номер 366(8), С. 1833 - 1839
Опубликована: Фев. 8, 2024
Abstract Herein, we report a photochemical synthesis of 1,4‐dicarbonyl containing quinoxalin‐2(1 H )‐ones through consecutive photoredox catalysed reactions. A wide range C3‐modified were obtained in 53–91% yields by this approach. Mechanistic studies including radical trapping, EPR studies, D‐labelling investigations, and many other control experiments well explained the proposed mechanism.
Язык: Английский
Процитировано
2