Photocatalyzed Acylation of Azauracil Derivatives with Aldehydes DOI
Yi Wang, Lianghong Liu,

Peng Deng

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(15), С. 11083 - 11087

Опубликована: Июль 24, 2024

A novel approach for the acylation of azauracil derivatives with aldehydes has been developed utilizing sodium decatungstate (NaDT) as a photocatalyst. This method demonstrates broad substrate tolerance and yields moderate to excellent outcomes. Notably, it aligns green chemistry principles by eliminating oxidants, eco-friendly energy sources, offering high scalability operational simplicity.

Язык: Английский

Recent Advances in Visible‐Light‐Enabled C3‐H Fluoroalkylation of Quinoxalin‐2(1H)‐ones DOI
Dong Ma, Xiaoxiang Wu, Tiebo Xiao

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(12)

Опубликована: Март 1, 2025

Abstract In light of the extensive application fluoroalkyl‐containing molecules and functionalized quinoxalin‐2(1 H )‐ones in medicinal chemistry functional materials, visible‐light‐enabled C3‐H fluoroalkylation has garnered significant attention. this review, we provide a detailed overview latest advancements rapidly evolving research area. We cover utilization various fluoroalkyl sources under conditions photocatalyst or without photocatalyst, discuss pertinent reaction conditions, mechanisms, substrate scope. Our objective is to help more chemists comprehend challenges opportunities within field, thereby fostering its development.

Язык: Английский

Процитировано

0

Access to quaternary-carbon-containing β-alkyl amides via persulfate-promoted domino alkylation/smiles rearrangement of alkenes DOI Creative Commons
Xiaohu Yang, Xiaoqing Wan, Wenchao Yang

и другие.

RSC Advances, Год журнала: 2025, Номер 15(20), С. 16183 - 16186

Опубликована: Янв. 1, 2025

An efficient radical alkylative annulation/arylation of N -(arylsulfonyl)acrylamide with 4-alkyl-1,4-dihydropyridines (DHP) was developed for synthesizing all-carbon quaternary-centered β-alkyl amides.

Язык: Английский

Процитировано

0

Photochemical Direct Mono/Di/Trifluoro‐Functionalization of Quinoxalin‐2(1H)‐ones DOI
D. Yogi Goswami,

Tanzina Firdoushi Borbhuyan,

Binoyargha Dam

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(21)

Опубликована: Июнь 1, 2025

Abstract Given the significant applications of quinoxalinones in medicinal, pharmaceutical, and organic chemistry, developing an efficient synthetic approach for their facile assembly has received substantial attention chemistry. Conversely, it been established that incorporating fluorine into molecules either alters or enhances physical, chemical, biological properties target molecules. In this context, synergic combination medicinal associated with quinoxaline‐2(1 H )‐ones, wide chemical landscape fluorine‐containing compounds, installing atom as a single di/tri‐substituted groups on C‐3 position quinoxalin‐2(1 )‐one under visible light irradiation is increasing academic scientific interests. mini‐review article, we covered recent progress achieved various light‐induced direct functionalization )‐ones accessing diverse C3‐substituted embedded mono/di/tri‐substituted fluorine. Despite discussing advantages, shortcomings, challenges reaction discovery, mechanistic rationalizations are also underscored.

Язык: Английский

Процитировано

0

Photo‐Induced Cross‐Dehydrogenative Coupling of Quinoxalin‐2(1H)‐ones with Aldehydes under Metal Free Conditions without an External Photocatalyst DOI
Chunmiao Wang,

Jiangtao Jiang,

Min Wang

и другие.

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(19)

Опубликована: Апрель 12, 2024

Abstract A simple strategy to 3‐acylated quinoxalin‐2(1 H )‐ones via a photo‐induced cross‐dehydrogenative coupling of with commercially available aldehyde under metal free conditions without an external photocatalyst was developed. In this transformation, various were generated in high yields good functional‐group tolerance.

Язык: Английский

Процитировано

2

Photocatalyzed Acylation of Azauracil Derivatives with Aldehydes DOI
Yi Wang, Lianghong Liu,

Peng Deng

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(15), С. 11083 - 11087

Опубликована: Июль 24, 2024

A novel approach for the acylation of azauracil derivatives with aldehydes has been developed utilizing sodium decatungstate (NaDT) as a photocatalyst. This method demonstrates broad substrate tolerance and yields moderate to excellent outcomes. Notably, it aligns green chemistry principles by eliminating oxidants, eco-friendly energy sources, offering high scalability operational simplicity.

Язык: Английский

Процитировано

2