Supported Nickel Nanoparticles as Catalyst in Direct sp3 C–H Alkylation of 9H‐Fluorene Using Alcohols as Alkylating Agent DOI Creative Commons
Raju Dey,

M. Vageesh,

Harsh Joshi

и другие.

Chemistry - An Asian Journal, Год журнала: 2024, Номер unknown

Опубликована: Окт. 14, 2024

Abstract Herein, we report an inexpensive first‐row transition metal Ni heterogeneous catalytic system for the C sp 3 ‐mono alkylation of fluorene using alcohols as alkylating agents via borrowing hydrogen strategy. The protocol displayed versatility with high yields desired products various types primary alcohols, including aryl/hetero aryl methanols, and aliphatic agents. catalyst NPs@N−C was synthesized high‐temperature pyrolysis strategy, ZIF‐8 sacrificial template. characterized by XPS, HR‐TEM, HAADF‐STEM, XRD ICP‐MS. is stable even in air at room temperature, excellent activity could be recycled 5 times without appreciable loss its activity.

Язык: Английский

Dynamic kinetic resolution and dynamic kinetic asymmetric transformation of atropisomeric biaryls DOI
Jie Zhang,

Xuan-Zhu Huo,

Yidan Liu

и другие.

Chem Catalysis, Год журнала: 2025, Номер unknown, С. 101329 - 101329

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

1

Photocatalytic Decarboxylative Alkylation of Cyclic Imine–BF3 Complexes: A Modular Route to Functionalized Azacycles DOI
Kamal Bhatt,

Alafate Adili,

Andrew Tran

и другие.

Journal of the American Chemical Society, Год журнала: 2024, Номер unknown

Опубликована: Сен. 12, 2024

Alkyl radicals generated via an acridine photocatalyzed decarboxylation reaction of feedstock carboxylic acids engage with a range cyclic imine-BF

Язык: Английский

Процитировано

5

Palladium-catalyzed C3-alkylation of indoles with alcohols via hydrogen borrowing cascade DOI
Zhiyuan Liu,

Mushou Cai,

Fumeng Yin

и другие.

Tetrahedron Letters, Год журнала: 2024, Номер 144, С. 155155 - 155155

Опубликована: Июнь 15, 2024

Язык: Английский

Процитировано

1

Iridium-Catalyzed Enantioconvergent Construction of Piperidines and Tetrahydroisoquinolines from Racemic 1,5-Diols DOI

Huanlin Diao,

Kexin Liu, Rong Yu

и другие.

Journal of the American Chemical Society, Год журнала: 2024, Номер unknown

Опубликована: Дек. 17, 2024

We report herein a one-step synthesis of valuable enantioenriched piperidines and tetrahydroisoquinolines from readily available racemic 1,5-diols. Key to the success is development new iridacycle catalysts that enable efficient redox-neutral construction two C–N bonds between diols amines in an enantioconvergent fashion. Mechanistic studies identified intriguing preferential oxidation secondary versus primary alcohol diol substrate by catalyst, which set challenging intermolecular amination aryl–alkyl-substituted as enantiodetermining step for this catalytic N-heterocycle synthesis. Application method preparation important drugs bioactive compounds also demonstrated.

Язык: Английский

Процитировано

1

Palladium-Catalyzed C3-Alkylation of Indoles with Alcohols Via Hydrogen Borrowing Cascade DOI

Hongjun Zhu,

Zhiyuan Liu,

Mushou Cai

и другие.

Опубликована: Янв. 1, 2024

Indole represents a privileged scaffold extensively used in drug design due to its promise improve both binding affinity and specificity receptors. Direct functionalization of indole framework is an efficient route achieve structurally diverse derivatives. Herein, highly regio-selective C3-alkylation indoles via hydrogen borrowing methodology (HBM) has been established using alcohols as the alkylation reagents over pallidum catalysis. This method enables synthesis C3-alkylated indoles, demonstrating high group adaptability alcohol substrates (20 examples, up 94% yield).

Язык: Английский

Процитировано

0

Supported Nickel Nanoparticles as Catalyst in Direct sp3 C–H Alkylation of 9H‐Fluorene Using Alcohols as Alkylating Agent DOI Creative Commons
Raju Dey,

M. Vageesh,

Harsh Joshi

и другие.

Chemistry - An Asian Journal, Год журнала: 2024, Номер unknown

Опубликована: Окт. 14, 2024

Abstract Herein, we report an inexpensive first‐row transition metal Ni heterogeneous catalytic system for the C sp 3 ‐mono alkylation of fluorene using alcohols as alkylating agents via borrowing hydrogen strategy. The protocol displayed versatility with high yields desired products various types primary alcohols, including aryl/hetero aryl methanols, and aliphatic agents. catalyst NPs@N−C was synthesized high‐temperature pyrolysis strategy, ZIF‐8 sacrificial template. characterized by XPS, HR‐TEM, HAADF‐STEM, XRD ICP‐MS. is stable even in air at room temperature, excellent activity could be recycled 5 times without appreciable loss its activity.

Язык: Английский

Процитировано

0