Mannitol‐based CO Surrogate for Palladium‐Catalyzed Alkoxycarbonylation
European Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 6, 2025
Abstract
Carbonylative
transformation
is
already
been
accepted
as
a
powerful
toolbox
in
synthetic
chemistry.
However,
the
manipulation
of
toxic
and
smell‐less
carbon
monoxide
gas
lagged
it
from
wide
range
applications.
Hence
developing
new
efficient
CO
surrogates
become
an
attractive
topic.
Herein,
we
developed
novel
mannitol‐based
surrogate
with
enhanced
loading
capacity
compared
to
known
organic
surrogates.
We
successfully
used
palladium‐catalyzed
alkoxycarbonylation
aryl
bromides
phenols
only
0.5
equivalent
required.
This
newly
designed
offers
additional
possibility
for
further
development
Язык: Английский
Palladium-catalyzed difluorocarbene transfer enables access to enantioenriched chiral spirooxindoles
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Окт. 1, 2024
Язык: Английский
Construction of Six-Membered Lactam and Lactone Structures via Ligand-Free Pd-Catalyzed C–H Activation/[5 + 1] Cyclization Carbonylation
Organic Letters,
Год журнала:
2024,
Номер
26(37), С. 7783 - 7788
Опубликована: Сен. 9, 2024
An
approach
for
the
ligand-free
Pd-catalyzed
C-H
activation/[5
+
1]
cyclization
carbonylation
by
employing
readily
available
ClCF
Язык: Английский
Synthesis of 2-Fluorinated Pyrazolo[1,5-a]pyridines via Base- Mediated [3+2] Cycloaddition of N-Aminopyridinium Salts with gem-Difluorostyrenes
New Journal of Chemistry,
Год журнала:
2024,
Номер
48(28), С. 12496 - 12500
Опубликована: Янв. 1, 2024
A
method
for
the
construction
of
2-fluoropyrazolo[1,5-
a
]pyridines
through
base-promoted
[3+2]
cycloaddition
N
-aminopyridinium
salts
with
gem
-difluorostyrenes
has
been
established.
Язык: Английский
The [PdCl2(Xantphos)] Complex Efficiently Catalyzed the Methoxycarbonylation of Iodobenzene to Methyl Benzoate
Catalysts,
Год журнала:
2024,
Номер
14(10), С. 660 - 660
Опубликована: Сен. 24, 2024
The
[PdCl2(Xantphos)]
complex,
in
comparison
with
several
[PdCl2(P–P)]
complexes
having
different
diphosphine
chelating
ligands
(P–P),
is
very
active
as
a
catalyst
for
the
carbonylation
of
iodobenzene
to
methyl
benzoate.
run
conditions
and
influence
cocatalysts
have
been
also
studied
further
improve
catalytic
activity.
optimization
system
allowed
obtain
TOFs
ca.
260,000
h−1.
addition
some
additives
able
reduce
possible
deactivation
increase
TOF
15%.
best
positive
results
were
obtained
by
adding
reducing
agents
such
ferrocene,
which
leads
higher
than
300,000
Язык: Английский
Electrocyclization for the Synthesis of Mono‐ and Disulfonyl‐substituted Pyrazoles From Sulfonyl Hydrazines and 1,3‐Diketones
ChemistrySelect,
Год журнала:
2024,
Номер
9(45)
Опубликована: Ноя. 26, 2024
Abstract
The
tunable
electrocyclic
reactions
for
the
synthesis
of
a
series
mono‐
and
disulfonyl‐substituted
pyrazoles
from
sulfonyl
hydrazines
1,3‐diketones
were
investigated
by
utilizing
inexpensive
electrolytes
under
electrochemical
conditions
in
an
undivided
cell.
When
n
Bu
4
NBF
was
used
as
electrolyte,
it
afforded
monosulfonyl‐substituted
pyrazoles.
By
contrast,
when
NH
I
gave
mechanistic
investigation
shows
that
they
all
underwent
free
radical
process
but
formed
N
‐centered
hydrazine
S‐centered
pyrazoles,
respectively.
Язык: Английский