Electrocyclization for the Synthesis of Mono‐ and Disulfonyl‐substituted Pyrazoles From Sulfonyl Hydrazines and 1,3‐Diketones DOI
Yuanyuan Wu,

Qiping Liu,

Zhitao Ning

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(45)

Published: Nov. 26, 2024

Abstract The tunable electrocyclic reactions for the synthesis of a series mono‐ and disulfonyl‐substituted pyrazoles from sulfonyl hydrazines 1,3‐diketones were investigated by utilizing inexpensive electrolytes under electrochemical conditions in an undivided cell. When n Bu 4 NBF was used as electrolyte, it afforded monosulfonyl‐substituted pyrazoles. By contrast, when NH I gave mechanistic investigation shows that they all underwent free radical process but formed N ‐centered hydrazine S‐centered pyrazoles, respectively.

Language: Английский

Mannitol‐based CO Surrogate for Palladium‐Catalyzed Alkoxycarbonylation DOI Creative Commons

Z. W. Liu,

Hefei Yang,

Zhipeng Bao

et al.

European Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Abstract Carbonylative transformation is already been accepted as a powerful toolbox in synthetic chemistry. However, the manipulation of toxic and smell‐less carbon monoxide gas lagged it from wide range applications. Hence developing new efficient CO surrogates become an attractive topic. Herein, we developed novel mannitol‐based surrogate with enhanced loading capacity compared to known organic surrogates. We successfully used palladium‐catalyzed alkoxycarbonylation aryl bromides phenols only 0.5 equivalent required. This newly designed offers additional possibility for further development

Language: Английский

Citations

0
Construction of Six-Membered Lactam and Lactone Structures via Ligand-Free Pd-Catalyzed C–H Activation/[5 + 1] Cyclization Carbonylation DOI

Chengxian Hu,

Lu Wang, Xue Yang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(37), P. 7783 - 7788

Published: Sept. 9, 2024

An approach for the ligand-free Pd-catalyzed C-H activation/[5 + 1] cyclization carbonylation by employing readily available ClCF

Language: Английский

Citations

1
Palladium-catalyzed difluorocarbene transfer enables access to enantioenriched chiral spirooxindoles DOI Creative Commons
Zhiwen Nie,

Keqin Wu,

Xiaohang Zhan

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 1, 2024

Language: Английский

Citations

1
Synthesis of 2-Fluorinated Pyrazolo[1,5-a]pyridines via Base- Mediated [3+2] Cycloaddition of N-Aminopyridinium Salts with gem-Difluorostyrenes DOI
Yang Feng, Yuanyuan Wu,

Zengjiang Yue

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(28), P. 12496 - 12500

Published: Jan. 1, 2024

A method for the construction of 2-fluoropyrazolo[1,5- a ]pyridines through base-promoted [3+2] cycloaddition N -aminopyridinium salts with gem -difluorostyrenes has been established.

Language: Английский

Citations

0
The [PdCl2(Xantphos)] Complex Efficiently Catalyzed the Methoxycarbonylation of Iodobenzene to Methyl Benzoate DOI Open Access

Luca Pietrobon,

Lucio Ronchin, Andrea Vavasori

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(10), P. 660 - 660

Published: Sept. 24, 2024

The [PdCl2(Xantphos)] complex, in comparison with several [PdCl2(P–P)] complexes having different diphosphine chelating ligands (P–P), is very active as a catalyst for the carbonylation of iodobenzene to methyl benzoate. run conditions and influence cocatalysts have been also studied further improve catalytic activity. optimization system allowed obtain TOFs ca. 260,000 h−1. addition some additives able reduce possible deactivation increase TOF 15%. best positive results were obtained by adding reducing agents such ferrocene, which leads higher than 300,000

Language: Английский

Citations

0
Electrocyclization for the Synthesis of Mono‐ and Disulfonyl‐substituted Pyrazoles From Sulfonyl Hydrazines and 1,3‐Diketones DOI
Yuanyuan Wu,

Qiping Liu,

Zhitao Ning

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(45)

Published: Nov. 26, 2024

Abstract The tunable electrocyclic reactions for the synthesis of a series mono‐ and disulfonyl‐substituted pyrazoles from sulfonyl hydrazines 1,3‐diketones were investigated by utilizing inexpensive electrolytes under electrochemical conditions in an undivided cell. When n Bu 4 NBF was used as electrolyte, it afforded monosulfonyl‐substituted pyrazoles. By contrast, when NH I gave mechanistic investigation shows that they all underwent free radical process but formed N ‐centered hydrazine S‐centered pyrazoles, respectively.

Language: Английский

Citations

0