DNA-Coupled AuNPs@CuMOF for Sensitive Electrochemical Detection of Carcinoembryonic Antigen
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(10), С. 11921 - 11930
Опубликована: Май 16, 2024
Detecting
preinvasive
tumors
before
the
onset
of
advanced
clinical
symptoms
represents
a
critical
advancement
in
improving
efficacy
early
medical
interventions
and
reducing
cancer-related
mortality
rates.
Immunosensors
have
emerged
as
preferred
choice
for
analyzing
oncomarkers
meeting
ever-increasing
demands
diagnostics.
Therefore,
quest
development
highly
specific
sensitive
immunosensors
remains
most
sought-after
to
open
new
avenues
personalized
healthcare
monitoring.
Here,
we
report
amplification-free
nonlabeled
DNA
framework-coupled
AuNPs@CuMOF
ultrasensitive
electrochemical
detection
carcinoembryonic
antigen
(CEA).
Upon
CEA
concentration
variation
from
0.0001
200
ng
mL–1,
proposed
biosensor
led
limit
(LOD)
0.25
pg
surpassing
previously
published
biosensors
that
rely
on
methods
aligns
with
those
based
amplification
techniques.
Furthermore,
suggested
immunosensor
demonstrated
auspiciously
high
specificity
sensitivity
detecting
human
serum
comparable
commercial
ELISA
within
relative
error
falling
between
6.25%
2.26%.
The
analytical
approach,
hinging
synergy
effect
CuMOF's
large
surface
area
mechanical
rigidity
three-dimensional
tetrahedron
structured
probes
(3D
TDNA),
obviously
broadens
potential
immunosensors,
offering
higher
lower
LOD.
this
work
is
not
only
an
expansion
CuMOF
exploitation
biosensing
but
also
major
milestone
diverse
biomarkers
settings
tumor
diagnosis.
Язык: Английский
Electrochemical Sensor Based on Tadpole-Shaped Au Nanostructures Supported on TiO2: Enhanced Detection of Nicotine in Electronic Cigarettes and Clinical Samples
Talanta,
Год журнала:
2025,
Номер
unknown, С. 127652 - 127652
Опубликована: Янв. 1, 2025
Язык: Английский
A novel perspective for estimating the passivation and energy storage characteristics in micro-mass coatings using CV, EIS, and EQCM techniques: Ultrahigh supercapacitor behaviors of Bismarck Brown R and Bismarck Brown Y polymer films
Journal of Energy Storage,
Год журнала:
2025,
Номер
115, С. 115985 - 115985
Опубликована: Фев. 27, 2025
Язык: Английский
Catalytic Competence of Gold Clusters Decorated Yellow 2 G Polymer Composite Film for Voltammetric Sensing of Dopamine and Nicotine in Biological Fluids
Synthetic Metals,
Год журнала:
2024,
Номер
309, С. 117765 - 117765
Опубликована: Окт. 9, 2024
Язык: Английский
Batch-fabricated full glassy carbon fibers for real-time tonic and phasic dopamine detection
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2025,
Номер
13
Опубликована: Фев. 28, 2025
Dopamine
(DA)
is
a
critical
neurotransmitter
that
key
in
regulating
motor
functions,
motivation,
and
reward-related
behavior.
Measuring
both
tonic
(baseline,
steady-state)
phasic
(rapid,
burst-like)
DA
release
essential
for
elucidating
the
mechanisms
underlying
neurological
disorders,
such
as
schizophrenia
Parkinson’s
disease,
which
are
associated
with
dysregulated
signaling.
Carbon
fiber
microelectrodes
(CFEs)
considered
gold
standard
measuring
rapid
changes
due
to
their
small
size
(5–10
µm),
biocompatibility,
flexibility,
excellent
electrochemical
properties.
However,
achieving
consistent
results
large-scale
production
of
CFE
arrays
through
manual
fabrication
poses
significant
challenges.
We
previously
developed
flexible
glassy
carbon
(GC)
microelectrode
(MEAs)
GC
fiber-like
MEAs
(GCF
MEAs)
detection
electrophysiology
recording.
also
demonstrated
feasibility
fabricating
MEA
electrodes
interconnects
made
from
single
homogeneous
material,
eliminating
need
metal
interconnections
addressing
related
concerns
about
electrical
mechanical
stability
under
prolonged
cycling.
Building
on
our
prior
experience,
we
now
present
double-etching
microfabrication
technique
batch
10
μm
×
µm
full
fibers
(fGCFs)
fGCF
arrays,
composed
entirely
material.
This
process
uses
2
µm-thick
low-stress
silicon
nitride
bottom
insulator
layer
fGCFs.
The
effectiveness
was
validated
scanning
electron
microscophy
(SEM)
energy
dispersive
X-ray
spectroscopy
(EDS)
elemental
analyses,
confirmed
uniformity
Si₃N₄
insulation
ensured
overall
integrity
Using
finite
element
analysis,
optimized
form
factor
achieve
self-penetration
up
3
mm
into
mouse
striatum
without
additional
support.
characterization
fGCFs
high
conductivity
wide
window.
ability
detect
using
fast
scan
cyclic
voltammetry
(FSCV)
square
wave
(SWV),
respectively,
vitro
vivo
.
With
sensitivity
detection,
combined
scalable
self-supporting
insertion
capability,
promising
sensors
offer
enhanced
practicality
comprehensive
monitoring.
Язык: Английский
A first in class disposable copolymer-graphite platform for electrocatalytic detection of dipicrylamine explosive in wastewater and soil samples
Microchemical Journal,
Год журнала:
2025,
Номер
unknown, С. 113930 - 113930
Опубликована: Май 1, 2025
Язык: Английский
Nitrogen-Doped Carbon Nanosheet/Poly(amidoamine) Dendrimer-based Electrochemical Sensor for Nicotine in Flavored Hookah Pipe Tobacco
Sesethu Makaluza,
Nyasha Midzi,
Foluke O. G. Olorundare
и другие.
Analytical Methods,
Год журнала:
2024,
Номер
16(44), С. 7518 - 7526
Опубликована: Янв. 1, 2024
Towards
the
nicotine
addiction
challenge
in
smoking
of
hookah
pipe
products,
we
hereby
present
development
an
electrochemical
sensor
for
detection.
A
nitrogen-doped
carbon
nanosheet
(N-CNS)/poly(amidoamine)
dendrimer
(PAMAM)
nanocomposite-modified
electrode
was
prepared
as
a
detection
analytical
and
real
samples.
The
N-CNSs
were
by
hydrothermal
method
dropcast
on
glassy
followed
electro-deposition
PAMAM
to
form
(GCE/N-CNSs/PAMAM).
characterized
with
electron
microscopy,
Raman
spectroscopy
FTIR.
voltammetry
impedance
spectroscopy.
N-CNS/PAMAM
enhanced
performance
towards
oxidation
nicotine.
achieved
limit
0.05
μM
linear
concentration
range
1.93-61.64
standard
showed
good
reproducibility,
repeatability,
selectivity.
successful
selectively
detecting
two
local
brands
tobacco
113-121
percent
recovery.
Nicotine,
up
0.35-0.39
mg
g
Язык: Английский
Sunset Yellow-Cu(II) Complex: DFT-supported electrochemical investigation and determination of Cu(II) ions in human serum and artificial sweat
Microchemical Journal,
Год журнала:
2024,
Номер
208, С. 112441 - 112441
Опубликована: Дек. 11, 2024
Язык: Английский
Development of a chitosan-gold nanocomposite based disposable pencil graphite electrode for the selective detection of thiram in peach juice
International Journal of Environmental & Analytical Chemistry,
Год журнала:
2024,
Номер
unknown, С. 1 - 15
Опубликована: Май 13, 2024
Hazardous
chemicals
that
are
mostly
employed
in
modern
agriculture
for
pest
management
have
caused
long-term
environmental
accumulation
as
well
major
issues
with
food
safety
and
human
health.
So,
there
is
an
urgent
demand
efficient
detection
methods
monitoring.
To
do
this,
the
most
contemporary
electrochemical
sensor
technology
suggested.
In
this
study,
a
new
has
been
developed
to
detect
thiram
(Th)
fungicide,
utilising
modified
activated
pencil
graphite
electrode
(a-PGE)
made
from
chitosan-gold
nanoparticle
polymer
(Ch-AuNPs)
first
time.
The
Ch-AuNPs/a-PGE
surface
characterised
using
cyclic
voltammetry
(CV),
scanning
electron
microscopy
(SEM),
energy
dispersive
X-ray
spectroscopy
(EDS).
Following
adjustments
experimental
parameters,
proposed
demonstrated
linear
calibration
curve
within
range
of
4.90–140
μM,
displaying
rapid
response
limit
1.15
μM.
exhibited
notable
selectivity,
stability,
reproducibility.
assess
its
practical
utility,
was
applied
analyse
peach
juice,
recovery
process
indicated
effectiveness
practical,
swift,
tool
pesticide
residue
Язык: Английский