Enzymatic acylation of raspberry anthocyanin: Evaluations on its stability and oxidative stress prevention

Food Chemistry, Год журнала: 2021, Номер 372, С. 130766 - 130766

Опубликована: Авг. 5, 2021

Язык: Английский

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Recent advances on the stability of dietary polyphenols

eFood, Год журнала: 2022, Номер 3(3)

Опубликована: Июнь 1, 2022

This review highlights on recent advances in the stability of polyphenols relation to their structure-stability relationship, new unstable products, and technologies stabilize polyphenols. Dietary are one most abundant groups phytochemicals food sources. Over 60,000 structurally diverse natural such as flavonoids, isoflavonoids, phenolic acids, stilbenoids, anthocyanins, flavan-3-ols were reported plants (Figure 1). Recently, more identified via metabolomics analysis based high-resolution mass spectrometry NMR spectroscopy. The epidemiological investigation clinical studies have confirmed that benefit human health by suppressing oxidative stress free radical scavenging, which play a key role preventing managing inflammation, diabetes, obesity, cardiovascular disease, cancer. Moreover, dietary supplements with or polyphenol-rich extracts been marketed reduce impact insufficient vegetables fruits intake. However, many highly prone oxidation and/or degradation during processing storage (Chandra et al., 2021). depends chemical structure, well environments pH temperature. Polyphenols affected variable extent different thermal non-thermal technologies. A wide range has applied improve storage. number publication "polyphenol stability" (Indexed WOS) significantly improved since 2011 breakout increasing happened last 3 years (2019–2021) 2). Several terms including concentration change, time, reaction kinetics, antioxidant potential characterize under certain designed experimental conditions. change conditions did not reflect nature degradation. namely early time (CT10) half (CT50) is reliable index compare between kinetics helpful predict control (Cao 2020, determination another approach exhibit (Asem 2020). main reason responsible for process. High-resolution MS pronouncedly convenient advanced method analyze polyphenol its products complex matrices. UPLC-Q-TOF-MSn UPLC-LTQ-Orbitrap-MSn widely screen structure degraded/oxidized 2020; Lin 2022; M. L. Wang H. Zhang 2022). spectroscopy important tool qualitative quantitative polyphenols, especially structural elucidation stereochemistry determination. Many factors systems contribute changes leading instability matrixes decided various biochemical reactions, value, photo/light, temperature, oxygen availability, metal ions, enzymes, proteins, nitrite salt, sulfur dioxide, other antioxidants, interactions constituents. value factor influencing polyphenols' 3). acidic environment stabilizes In alkaline solution, degradation, dimerization, always tend happen (M. For example, malvain 3-O-glucoside exhibits colors content total anthocyanins reduces heating neutral (Oancea, temperature affecting Lower protect oxidase, peroxidase, glycosidase, esterase will be released catalyzed reactions when plant cells destroyed (Montoya Some decomposed saliva form acids (Rogozinska & Biesaga, dramatically due variations. can changed modifications, hydroxylation, glycosylation, acylation, pigmentation. It looks like hydroxylation stability, while modifications hydroxyl influenced following order resorcinol-type > catechol-type pyrogallol-type, pyrogallol-type being least stable. Co-pigmentation also occurs hydrogen bonding flavonoids. contrast, any glycosylation enhance stability. trans trans-resveratrol showed much than cis (Kosović 3-O-caffeoylquinic acid stable 4-O-caffeoylquinic (D. acylated non-acylated reactive molecules undergo series enzymatic components cells, resulting system (Wei Enzymatic browning decarboxylated dihydro-1,4-benzothiazine derivatives major intermediates finally produce pigment (Mertens During processing, rapidly converted into mediated heat. there few mechanisms reports hydrolysis systems. antioxidants from sources don't matrix. unpredictable influence improving inhibitory activity matrix reported. Ascorbic flavonols' but weaken (Hanuka Katz purified higher strawberry extract. cinnamon clove extract hardly chokeberry juice (Sidor Processing cranberries sweetened dried reduced proanthocyanidins (Kovacev Interactions polysaccharides significant consequences bioavailability extractability With aid analysis, it identify oxidation, nucleophilic attack cleavage. quercetin boiling water 3,5-dihydroxyphenylglyoxylic acid, 1,3,5-trihydroxybenzene, 3,4,5-trihydroxybenzoic 2,4,6-trihydroxybenzoic 2,3-dihydro-2,3′,4′,5,7-pentahydroxy-3-oxoflavone, dimers, quinones 4). Flavonols catechol pyrogallol substitution pattern ring B readily formed dimers oxidized phosphate-buffered saline (pH = 7.4) at 4°C within 5 s 4) Epimerization tea catechins high (Xu 2019). Tea auto-oxidized degraded gallocatechin gallic (Wu Chlorogenic tends isomerized neochlorogenic cryptochlorogenic further extraction (Ianni 3- isomers yield phloroglucinaldehyde C3–C4 cleavage C2–C3 3,5,7-trihydroxycoumarin 2,4,6-trihydroxyphenylacetic 5; Fenger anthocyanin phloroglucinol Y. stilbenoids methanol solution UV irradiation intramolecular cyclization phenanthrene structures (Latva-Mäenpää solid trans-stilbenoids sensitive UV/fluorescent light, elevated humidity, atmospheric oxidants ambient novel developing processing. Encapsulation, microcapsule, lyophilization, conjugation biomacromolecules, cold plasma typical innovative sustainable provide advantages 2021; Choudhury Jagtiani, β-cyclodextrin/protein/polysaccharide microencapsulation encapsulation solubility, safety, bioavailability, biocompatibility, bioactivity 6). β-cyclodextrin improves bioaccessibility mulberry (Li 2020), olive pomace (Radić citrus (Caballero Application polyphenol- protein/polysaccharide interaction fabrication, nanoparticles, emulsion, EGCG, resveratrol, quercetin, chlorogenic isoflavone. Nanopolyphenols efficient delivery therapeutic efficacy, possibly biocompatibility (Rambaran Nordström, exogenous derivatives. process foods different, makes complicated. How law difficult problem. exist microstructure forms physical (embedded matrix), bound (interacting biomacromolecules), insoluble (Ren Free easily extracted food, so focus biological properties (Domínguez-Fernández Compared greatly improved, biomacromolecules small reacting, protective ability related affinity polyphenols-biomacromolecule interactions. Although fruit account 20%–60% content, however, clarified study was supported Ramón y Cajal grant (RYC2020-030365-I).

Язык: Английский

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Polysaccharides as Carriers of Polyphenols: Comparison of Freeze-Drying and Spray-Drying as Encapsulation Techniques

Molecules, Год журнала: 2022, Номер 27(16), С. 5069 - 5069

Опубликована: Авг. 9, 2022

Polyphenols have received great attention as important phytochemicals beneficial for human health. They a protective effect against cardiovascular disease, obesity, cancer and diabetes. The utilization of polyphenols natural antioxidants, functional ingredients supplements is limited due to their low stability caused by environmental processing conditions, such heat, light, oxygen, pH, enzymes so forth. These disadvantages are overcome the encapsulation different methods in presence polyphenolic carriers. Different technologies been established with purpose decreasing polyphenol sensitivity creation more efficient delivery systems. Among them, spray-drying freeze-drying most common encapsulation. This review will provide an overview scientific studies which from sources were encapsulated using these two drying methods, well impact polysaccharides used carriers

Язык: Английский

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Natural products as chemo-radiation therapy sensitizers in cancers

Biomedicine & Pharmacotherapy, Год журнала: 2022, Номер 154, С. 113610 - 113610

Опубликована: Авг. 25, 2022

Cancer is a devastating disease and the second leading cause of death worldwide. Surgery, chemotherapy (CT), and/or radiation therapy (RT) are treatment choice for most advanced tumors. Unfortunately, failure due to intrinsic acquired resistance current CT RT significant challenge associated with poor patient prognosis. There an urgent need develop identify agents that can sensitize tumor cells chemo-radiation (CRT) minimal cytotoxicity healthy tissues. While many recent studies have identified underlying molecular mechanisms therapeutic targets CRT failure, using small molecule inhibitors chemo/radio tumors high toxicity increased morbidity. Natural products long been used as chemopreventive in cancers. Combining these compounds standard chemotherapeutic or has shown synergistic effects on cancer cell overall improvement survival. Based available data, there strong evidence natural robust potential along their well-known solid This review article reports updated literature different sensitizers first discussing together cancer.

Язык: Английский

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Kaempferol and atherosclerosis: From mechanism to medicine

Critical Reviews in Food Science and Nutrition, Год журнала: 2022, Номер 64(8), С. 2157 - 2175

Опубликована: Сен. 13, 2022

Natural products possess pleiotropic cardiovascular protective effects owing to their anti-oxidation, anti-inflammation and anti-thrombotic properties. Kaempferol, (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), is a kind of naturally occurring flavonoid existing in many common fruits vegetables (e.g., onions, broccoli, strawberries grapes) particularly traditional Chinese medicine as exemplified by Ginkgo biloba. Epidemiological, preclinical clinical studies have revealed an inverse association between the consumption kaempferol-containing foods medicines risk developing diseases. Numerous translational experimental animal models cultured cells demonstrated wide range pharmacological activities kaempferol. In this article, we reviewed antioxidant, anti-inflammatory cardio-protective kaempferol elucidated potential molecular basis therapeutic capacity focusing on its anti-atherosclerotic effects. Overall, review presents health benefits plants reflects possible drug candidate prevent treat atherosclerosis, underlying pathology most

Язык: Английский

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Comparison of microwave, ultrasound and ultrasound-microwave assisted solvent extraction methods on phenolic profile and antioxidant activity of extracts from jackfruit (Artocarpus heterophyllus Lam.) pulp

LWT, Год журнала: 2022, Номер 173, С. 114395 - 114395

Опубликована: Дек. 28, 2022

This study aimed to investigate the impact of different solvents (water, 60% methanol, ethanol and acetone) methods (conventional solvent extraction, ultrasound-assisted microwave-assisted extraction ultrasound-microwave assisted extraction) on phenolic profile antioxidant activity jackfruit (Artocarpus heterophyllus Lam.) pulp. The Folin-Ciocalteu assay was used determine total content (TPC), measured by DPPH ABTS assays. profiles in extracts were identified using UPLC-ESI-Q-TOF-MS/MS technique. results showed that significant differences (p < 0.05) TPC found among methods, with had highest (2.40 mg GAE/g) compared obtained from other methods. Meanwhile, radical cation ethanol-MAE extracts. Correlation analysis further a positive correlation between (R2 > 0.8, p 0.001). Seventy-eight compounds analysis. most abundant pulp negative mode, being effective. quantity extracted varied indicated effects phytochemical characteristics.

Язык: Английский

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Recent advances in dietary flavonoids for management of type 2 diabetes

Current Opinion in Food Science, Год журнала: 2022, Номер 44, С. 100806 - 100806

Опубликована: Янв. 8, 2022

Язык: Английский

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Omega‐3 polyunsaturated fatty acid encapsulation system: Physical and oxidative stability, and medical applications

Food Frontiers, Год журнала: 2022, Номер 3(2), С. 239 - 255

Опубликована: Янв. 14, 2022

Abstract The benefits of omega‐3 (ω‐3) polyunsaturated fatty acids (PUFAs) to human health and the therapeutic properties diseases have been widely identified. However, due abundant double bonds, they are sensitive environmental conditions which cause oxidative deterioration. This is one main factors limiting their application. encapsulation ω‐3 PUFAs an effective way improve oxidation stability. review summarizes recent advances in different forms systems, such as emulsions, liposomes, microcapsules, liquid crystalline. Particular emphasis given effects food‐derived biopolymers wall materials (proteins, polysaccharides, esters) on efficiency stability systems. In addition, natural antioxidants (polyphenols, carotenoids, flavonoids, plant essential oils, etc.) antioxidant enhancement system based discussed. Different systems proven be used supplements medical field. regulation improvement animal human, related central nervous system, retina, lung, kidney tissue cell, systematically

Язык: Английский

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Emerging applications of metabolomics in food science and future trends

Food Chemistry X, Год журнала: 2022, Номер 16, С. 100500 - 100500

Опубликована: Ноя. 9, 2022

Metabolomics is a relatively new component in systems biology that focuses on the high-throughput characterization of small molecular metabolites biological systems. It widely used several scientific fields, particularly food. Due to its excellent detection and prediction capacities, metabolomics well suited analyze such complex matrix. This review emphasizes most commonly food analytical technologies with focus novel approaches have emerged recent years, highlighting their suitability for samples analysis as aided by chemometric data visualization. A comparison presented among different platforms prioritization which metabolite classes Application are context composition analysis, quality safety, traceability. Furthermore, constraints limitations actual applications explored, bringing insights into use science maximize application potential major industrial sector.

Язык: Английский

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Co-encapsulation of chlorogenic acid and cinnamaldehyde essential oil in Pickering emulsion stablized by chitosan nanoparticles

Food Chemistry X, Год журнала: 2022, Номер 14, С. 100312 - 100312

Опубликована: Апрель 18, 2022

Most of the current research only explored loading an active substance in packaging. In this study, cinnamaldehyde essential oil (CEO) and chlorogenic acid (CA) were co-encapsulated chitosan (CS) nanoparticles based Pickering emulsion. The morphology wettability CS-CA particles determined. addition, physicochemical characterizations stability emulsion also investigated. Results showed that was improved with increasing ratios CS to CA, which is helpful stabilize CEO stabilized by best using CA 1:0.75 minimum creaming index value 26.5 ± 4.6% after 5 days storage. These overall results presented work demonstrate, for first time, potential co-encapsulation water-soluble water-insoluble ingredients.

Язык: Английский

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