Special journal of the Medical Academy and other Life Sciences,
Год журнала:
2024,
Номер
2(2)
Опубликована: Фев. 25, 2024
Introduction.
Abnormal
uterine
bleeding
(AUB)
describes
that
varies
from
the
usual
parameters
of
a
normal
menstrual
cycle
[3].
AUB
is
one
most
common
gynecologic
problems
among
women
reproductive
age.
Approximately
one-third
experience
at
some
point
in
their
lives
[1].
Purpose
study.
This
study
aims
to
explore
prevalence
and
causes
Maldivian
age
who
have
experienced
menstruation.
Materials
method.
An
online
questionnaire
survey
was
conducted
reproductive-age
Maldivians
The
population
analyzed
through
exploratory
data
analysis.
Research
result.
From
collected,
out
110
participants,
37
(33.6%)
individuals
reported
having
irregular
menses.
Additionally,
22
(20%)
menorrhagia.
Moreover,
16
(14.5%)
polymenorrhea,
14
(12.7%)
amenorrhea
9
(8.2%)
oligomenorrhea.
According
interpreted
pictogram,
it
observed
35
participants
self-reporting
heavy
bleeding,
merely
20%
(7
individuals)
actually
had
blood
loss
(MBL)
exceeding
80ml.
average
these
calculated
be
113
ml,
highlighting
notable
disparity
between
subjective
perception
objective
data.
Out
68
flow,
4
MBL
80ml,
with
mean
116.19
ml.
entire
group,
44
(40%)
diagnosis
polycystic
ovarian
syndrome
(PCOS),
18
(16.4%)
cysts.
Furthermore,
2
(1.8%)
endometriosis,
fibroids
and,
mentioned
cervical
polyp,
1
(0.9%)
an
endometrial
polyp.
Conclusion.
Using
FIGO
system
as
gateway
simplifies
process
investigating
[2].
Based
on
criteria
set
by
1,
only
46
(41.8%)
were
found
cycle.
remaining
64
(58.2%)
AUB.
total
29
PCOS.
These
findings
suggest
significant
association
PCOS
within
population.
Human Reproduction,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 26, 2025
Abstract
STUDY
QUESTION
Does
definitive
occlusion
of
uterine
arteries
have
a
short-
or
long-term
impact
on
ovarian
reserve
markers
in
reproductive-age
women
undergoing
laparoscopic
myomectomy?
SUMMARY
ANSWER
Preventive
artery
(UAO)
during
myomectomy
reduces
intraoperative
blood
loss
but
does
not
serum
AMH
levels
after
and
follow-up
women.
WHAT
IS
KNOWN
ALREADY
Uterine
leiomyomas
are
the
most
common
benign
tumours
reproductive
age.
For
symptomatic
willing
to
retain
their
uterus,
especially
for
future
pregnancy,
current
gold
standard
is
surgical
subserous/intramural
leiomyoma.
Temporary
can
be
performed
control
bleeding
surgery
its
still
unclear.
A
single
randomized
trial
with
1-year
demonstrated
that
temporary
bilateral
UAO
slightly
decreased
at
postoperative
day
2
has
no
significant
3,
6,
12
months
surgery.
DESIGN,
SIZE,
DURATION
We
conducted
controlled
2-year
evaluating
effect
via
sequential
measures
AFC
by
ultrasound
assessment.
The
study
included
58
leiomyoma
type
FIGO
3
6
scheduled
between
July
2015
October
2021.
Patient
allocation
was
disclosed
surgeon
just
before
starting
procedure;
were
blinded
group
throughout
study.
PARTICIPANTS/MATERIALS,
SETTING,
METHODS
Patients
two
groups:
(laparoscopic
preventive
arteries)
(n
=
29
women)
no-UAO
without
intra-myometrial
injection
vasoconstrictive
agents)
(N
women).
Serum
evaluated
baseline
(T0)
followed
1
month
(T1),
(T3),
(T6),
(T12),
24
(T24)
Intraoperative
loss,
evolution
pain
symptoms,
recurrence
also
as
secondary
outcomes.
Pregnancies
live
births
monitored.
MAIN
RESULTS
AND
THE
ROLE
OF
CHANCE
Women
both
groups
did
differ
characteristics
terms
age,
body
mass
index,
ethnicity,
parity,
wish
become
pregnant,
hormonal
treatment,
number
size,
haemoglobin
levels,
AFC.
mean
operative
time
similar
groups.
Mean
average
138
(±104)
ml
versus
436
(±498)
controls
(P
<
0.001).
In
group,
0%
had
an
>500
32.1%
0.01).
Regarding
clinical
patients
menstrual
flow
last
visit
(24
months)
compared
improvement
dysmenorrhea
same
trend
reduction
risk
any
(T1,
T3,
T6,
T12,
T24)
non-inferiority
margin
[−3.5
pmol/l].
Differences
means
95%
CI
(in
parentheses)
follows:
T1
−0.11
(−2.14
2.40),
T3
−0.25
(−2.36
2.21),
T6
0.81
(−2.69
3.84),
T12
−0.95
(−3.15
1.33),
T24
1.18
(−1.95
3.82).
time,
however,
could
demonstrated,
presumably
due
large
variability
this
measurement.
LIMITATIONS,
REASONS
FOR
CAUTION
Our
sample
size
calculated
detect
clinically
relevant
difference
least
two-thirds
SD
we
cannot
exclude
larger
might
revealed
smaller
AMH.
WIDER
IMPLICATIONS
FINDINGS
compromise
used
safely
improve
perioperative
Incorporating
measure
may
enhance
safety
procedure.
FUNDING/COMPETING
INTEREST(S)
Funded
Department
Paediatrics,
Gynecology
Obstetrics
Geneva
University
Hospitals.
There
competing
interests
declare.
TRIAL
REGISTRATION
NUMBER
NCT02563392.
DATE
9
2015.
FIRST
PATIENT’S
ENROLMENT
International Journal of Gynecology & Obstetrics,
Год журнала:
2023,
Номер
162(S2), С. 89 - 92
Опубликована: Авг. 1, 2023
Abstract
The
symptom
of
heavy
menstrual
bleeding
and
the
frequently
associated
condition
iron
deficiency
(ID)
individually
collectively
adversely
impact
lives
women
girls
reproductive
age
in
various
ways.
insidious
but
sometimes
profound
effects
periconceptual
ID
on
developing
fetus
may
continue
throughout
individual's
life
with
consequences
that
are
also
felt
by
families,
friends,
society
at
large.
Unfortunately,
most
instances,
current
healthcare
policies
not
designed
to
address
plethora
issues
a
fashion
will
result
meaningful
improvement
health
other
outcomes
affect
both
individuals
society.
Identification
prioritization
many
evidence
gaps
be
an
essential
component
strategy
for
change.
This
article
identifies
describes
provides
direction
investigators
those
involved
policy.
IEEE Access,
Год журнала:
2024,
Номер
12, С. 9292 - 9307
Опубликована: Янв. 1, 2024
This
article
evolved
because
several
instances
of
anemia
are
still
discovered
too
late,
especially
in
communities
with
limited
medical
resources
and
access
to
laboratory
tests.
Invasive
diagnostic
technologies
expensive
expenses
additional
impediments
early
diagnosis.
To
detect
anemia,
an
effective,
accurate,
non-invasive
method
is
required.
In
this
study,
the
conjunctival
image
eye
analyzed
as
a
detecting
anemia.
Various
model
approaches
were
tested
endeavor
categorize
anemic
healthy
patients
accurately
possible.
The
Support
Vector
Machine
(SVM)
algorithm-integrated
MobileNetV2
was
determined
be
most
effective
plan.
With
combination,
accuracy
93%,
sensitivity
91%,
specificity
94%.
These
findings
show
that
can
successfully
identify
while
identifying
patients.
offers
means
on,
making
it
promising
for
use
clinical
settings.
SVM+MobileNetV2
technique
relies
on
images
conjunctiva
has
potential
improve
healthcare
by
people
who
may
have
had
earlier.
stands
out
solid
option
efficient
precise
diagnosis
when
accuracy,
sensitivity,
balanced.
Drugs in Context,
Год журнала:
2024,
Номер
13, С. 1 - 19
Опубликована: Июль 2, 2024
Abnormal
uterine
bleeding
(AUB)
is
an
acute/chronic
variation
in
the
normal
menstrual
cycle
that
affects
adolescents,
women
of
reproductive
age
and
perimenopausal
women.
AUB
approximately
3-30%
reproductive-aged
worldwide,
reduces
their
quality
life
productivity
whilst
increasing
overall
healthcare
burden.
Its
management
requires
thorough
medical
evaluation
individualized
treatment.
Depending
on
severity
cause
AUB,
its
treatment
ranges
from
lifestyle
modifications
hormonal
therapies
to
more
invasive
procedures
or
surgery.
Although
therapy
preferred
first-line
measure
available
pharmacological
options
have
various
adverse
effects.
There
exists
a
need
for
safer
efficient
regimens
with
high
patient
compliance
effectively
treat
AUB.
Norethisterone,
also
known
as
norethindrone,
widely
used
synthetic
analogue
progestogen.
Controlled
release
formulations
norethisterone/
norethisterone
acetate
help
maintain
constant
drug
levels
blood
exert
minimal
side-effects;
therefore,
they
are
promising
therapeutic
agents
effective
management.
The
present
review
summarizes
epidemiology
diagnosis
focus
safety,
efficacy
tolerability
We
report
case
40-year-old
woman,
who
was
treated
NETA
tablets.
resulted
favourable
outcomes,
satisfaction.
Journal of Clinical Medicine,
Год журнала:
2024,
Номер
13(23), С. 7086 - 7086
Опубликована: Ноя. 23, 2024
Abnormal
uterine
bleeding
(AUB)
is
a
common
gynecological
complaint
affecting
women
of
reproductive
age.
This
study
aimed
to
explore
the
management
AUB
using
FIGO
PALM-COEIN
classification
system.
Journal of Clinical Medicine,
Год журнала:
2024,
Номер
13(24), С. 7538 - 7538
Опубликована: Дек. 11, 2024
This
review
evaluates
the
advances
in
early
detection
and
diagnosis
of
endometrial
cancer
(EC),
emphasizing
growing
importance
minimally
invasive
techniques
novel
biomarkers.
Current
diagnostic
protocols
for
EC
rely
heavily
on
procedures
such
as
transvaginal
ultrasound
(TVU),
hysteroscopy,
biopsy,
which,
although
effective,
can
be
overly
burdensome
patients
inefficient
asymptomatic
or
low-risk
populations.
As
there
is
no
consensus
screening
high-risk
general
populations,
recent
studies
have
explored
alternative
methods
using
biofluids
genomic
biomarkers
to
improve
sensitivity
specificity
facilitate
access
patients.
summarizes
findings
DNA
methylation
markers,
circulating
tumor-derived
nucleic
acids,
potential
liquid
biopsy
approaches
EC.
These
innovations
may
not
only
streamline
but
also
reduce
need
procedures.
highlights
these
integrated
seamlessly
into
existing
cervical
programs,
which
could
transform
support
development
personalized,
less
The European Research Journal,
Год журнала:
2024,
Номер
10(4), С. 414 - 425
Опубликована: Июнь 27, 2024
Abnormal
uterine
bleeding
(AUB)
is
a
common
gynecological
complaint
among
premenopausal
women,
encompassing
wide
range
of
underlying
disorders
that
complicate
diagnosis
and
management.
The
evolving
paradigms
in
medical
science
now
incorporate
advanced
imaging
techniques,
personalized
medicine,
molecular
diagnostics
to
improve
the
accuracy
diagnoses
effectiveness
treatment
plans.
This
review
examines
recent
advancements
diagnostic
approach,
including
use
transvaginal
ultrasonography,
hysteroscopy,
biomarker
analysis,
which
have
significantly
refined
identification
endometrial
pathologies.
Furthermore,
we
discuss
shift
towards
individualized
strategies
consider
patient-specific
factors
such
as
age,
reproductive
plans,
comorbidities,
facilitating
tailored
therapies.
Special
attention
given
role
therapies
ranging
from
hormonal
treatments
novel
non-hormonal
drugs,
well
consideration
minimally
invasive
surgical
options
part
comprehensive
management
strategy.
By
integrating
current
research
findings
with
clinical
practice
guidelines,
this
article
aims
provide
synthesized
view
dynamic
field
AUB
management,
proposing
multidisciplinary
approach
enhance
patient
outcomes
women.