Multifunctional hydrogel dressing promotes wound healing by reprogramming the infection-related wound microenvironment DOI

Yaqi Xi,

Shuo Zhang, Meng-Ru Wu

и другие.

Journal of Materials Science, Год журнала: 2024, Номер 59(35), С. 16660 - 16677

Опубликована: Сен. 1, 2024

Язык: Английский

Antibacterial and Metalloproteinase-Inhibited Zinc-Doped Bioactive Glass Nanoparticles for Enhancing Dentin Adhesion DOI

Xiao Cao,

Jieyong Jia, Linyue Wu

и другие.

Journal of Dentistry, Год журнала: 2025, Номер 154, С. 105610 - 105610

Опубликована: Фев. 4, 2025

Язык: Английский

Процитировано

0
Hybrid flexible dressings with rapid gelation promote healing of difficult-to-treat infected wounds DOI Creative Commons

Mengchen Chen,

Junhao Sui,

Licai Miao

и другие.

Materials & Design, Год журнала: 2025, Номер unknown, С. 113952 - 113952

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
A Multifunctional PEEK Composite Scaffold with Immunomodulatory, Angiogenic, and Osteogenic Properties for Enhanced Bone Regeneration DOI Open Access

Mengen Zhao,

Han Yang,

Qianwen Yang

и другие.

Polymers, Год журнала: 2025, Номер 17(9), С. 1206 - 1206

Опубликована: Апрель 28, 2025

Polyetheretherketone (PEEK) is a widely used material in bone tissue engineering due to its favorable mechanical properties and radiolucency. However, bioinert nature lack of osteogenic activity restrict ability support effective regeneration. In this study, novel APS-coated plasma-treated sulfonated bioactive PEEK scaffold (APS/PSBPK) was developed overcome these limitations. The integrates strontium-doped glass (SrBG) enhance biocompatibility potential, while astragalus polysaccharide (APS) incorporated via plasma cleaning modulate immune responses promote vascularization. vitro studies demonstrated that the APS/PSBPK facilitates M2 macrophage polarization, reduces pro-inflammatory cytokines, enhances secretion anti-inflammatory factors. It also promotes endothelial cell migration angiogenesis supporting adhesion, proliferation, differentiation rBMSCs. vivo experiments revealed effectively regulates microenvironment, vascularization, accelerates Thus, composite serves as multifunctional biomaterial with significant potential for applications repair regeneration by combining immunomodulation, angiogenesis, osteogenesis.

Язык: Английский

Процитировано

0
Multifunctional hydrogel dressing promotes wound healing by reprogramming the infection-related wound microenvironment DOI

Yaqi Xi,

Shuo Zhang, Meng-Ru Wu

и другие.

Journal of Materials Science, Год журнала: 2024, Номер 59(35), С. 16660 - 16677

Опубликована: Сен. 1, 2024

Язык: Английский

Процитировано

2