Multifunctional hydrogel dressing promotes wound healing by reprogramming the infection-related wound microenvironment DOI

Yaqi Xi,

Shuo Zhang, Meng-Ru Wu

et al.

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(35), P. 16660 - 16677

Published: Sept. 1, 2024

Language: Английский

Antibacterial and Metalloproteinase-Inhibited Zinc-Doped Bioactive Glass Nanoparticles for Enhancing Dentin Adhesion DOI

Xiao Cao,

Jieyong Jia, Linyue Wu

et al.

Journal of Dentistry, Journal Year: 2025, Volume and Issue: 154, P. 105610 - 105610

Published: Feb. 4, 2025

Language: Английский

Citations

0
Hybrid flexible dressings with rapid gelation promote healing of difficult-to-treat infected wounds DOI Creative Commons

Mengchen Chen,

Junhao Sui,

Licai Miao

et al.

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113952 - 113952

Published: April 1, 2025

Language: Английский

Citations

0
A Multifunctional PEEK Composite Scaffold with Immunomodulatory, Angiogenic, and Osteogenic Properties for Enhanced Bone Regeneration DOI Open Access

Mengen Zhao,

Han Yang,

Qianwen Yang

et al.

Polymers, Journal Year: 2025, Volume and Issue: 17(9), P. 1206 - 1206

Published: April 28, 2025

Polyetheretherketone (PEEK) is a widely used material in bone tissue engineering due to its favorable mechanical properties and radiolucency. However, bioinert nature lack of osteogenic activity restrict ability support effective regeneration. In this study, novel APS-coated plasma-treated sulfonated bioactive PEEK scaffold (APS/PSBPK) was developed overcome these limitations. The integrates strontium-doped glass (SrBG) enhance biocompatibility potential, while astragalus polysaccharide (APS) incorporated via plasma cleaning modulate immune responses promote vascularization. vitro studies demonstrated that the APS/PSBPK facilitates M2 macrophage polarization, reduces pro-inflammatory cytokines, enhances secretion anti-inflammatory factors. It also promotes endothelial cell migration angiogenesis supporting adhesion, proliferation, differentiation rBMSCs. vivo experiments revealed effectively regulates microenvironment, vascularization, accelerates Thus, composite serves as multifunctional biomaterial with significant potential for applications repair regeneration by combining immunomodulation, angiogenesis, osteogenesis.

Language: Английский

Citations

0
Multifunctional hydrogel dressing promotes wound healing by reprogramming the infection-related wound microenvironment DOI

Yaqi Xi,

Shuo Zhang, Meng-Ru Wu

et al.

Journal of Materials Science, Journal Year: 2024, Volume and Issue: 59(35), P. 16660 - 16677

Published: Sept. 1, 2024

Language: Английский

Citations

2