International Journal of Biological Macromolecules, Год журнала: 2022, Номер 222, С. 1723 - 1733
Опубликована: Окт. 8, 2022
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2022, Номер 222, С. 1723 - 1733
Опубликована: Окт. 8, 2022
Язык: Английский
ACS Nano, Год журнала: 2021, Номер 15(12), С. 18895 - 18930
Опубликована: Дек. 6, 2021
Light is an attractive tool that has a profound impact on modern medicine. Particularly, light-based photothermal therapy (PTT) and photodynamic (PDT) show great application prospects in the prevention of wound infection promoting healing. In addition, hydrogels have shown advantages field dressings due to their excellent biochemical effects. Therefore, multifunctional photoresponsive (MPRHs) integrate light are increasingly used biomedicine, especially repair. However, comprehensive review MPRHs for regeneration still lacking. This first focuses various types prepared by diverse photosensitizers, agents (PHTAs) including transition metal sulfide/oxides nanomaterials, nanostructure-based PHTAs, carbon-based conjugated polymer or complex-based and/or (PHDAs) such as ZnO-based, black-phosphorus-based, TiO2-based, small organic molecule-based PHDAs. We also then discuss how PTT, PDT, photothermal/photodynamic synergistic can modulate microenvironments bacteria inhibit infection. Overall, with both therapeutic tissue capabilities been discussed existing challenges, well future research directions management argued.
Язык: Английский
Процитировано
431Advanced Science, Год журнала: 2021, Номер 8(19)
Опубликована: Авг. 5, 2021
Healthcare-acquired infections as well increasing antimicrobial resistance have become an urgent global challenge, thus smart alternative solutions are needed to tackle bacterial infections. Antibacterial materials in biomedical applications and hospital hygiene attracted great interest, particular, the emergence of surface design strategies offer effective antibiotics, thereby preventing possible development resistance. In this review, recent progress on advanced modifications prevent addressed comprehensively, starting with key factors against adhesion, followed by varying that can inhibit biofilm formation effectively. Furthermore, "super antibacterial systems" through pre-treatment defense targeted bactericidal system, proposed evidence clinical potential. Finally, advantages future challenges resist healthcare-associated discussed, promising prospects developing novel materials.
Язык: Английский
Процитировано
297Materials Science and Engineering R Reports, Год журнала: 2021, Номер 145, С. 100610 - 100610
Опубликована: Март 30, 2021
Язык: Английский
Процитировано
220Journal of Controlled Release, Год журнала: 2023, Номер 363, С. 180 - 200
Опубликована: Сен. 27, 2023
Язык: Английский
Процитировано
143Journal of Alloys and Compounds, Год журнала: 2022, Номер 904, С. 164091 - 164091
Опубликована: Фев. 4, 2022
Язык: Английский
Процитировано
115Bioactive Materials, Год журнала: 2022, Номер 23, С. 129 - 155
Опубликована: Ноя. 11, 2022
One of the challenges posed by current antibacterial therapy is that expanded and massive use antibiotics endows bacteria with ability to resist almost all kinds antibiotics. Therefore, developing alternative strategies for efficient treatment urgently needed. Antibacterial gas has attracted much attention in past decade. Nitric oxide (NO), carbon monoxide (CO), sulfur dioxide (SO2), hydrogen sulfide (H2S), (H2) are not only known as endogenous signaling molecules, but also play critical roles many pathological processes. These gases considered attractive bactericidal agents because they able kill bacteria, disperse biofilms, promote bacteria-infected wound healing while avoiding resistance. In this review, we discuss properties these gases, well recent advances gas-involving systems antibacterial, antibiofilm, applications. Moreover, summarize various donors utilized treatment. We hope review will shed new light on future design applications advanced therapy.
Язык: Английский
Процитировано
90Materials & Design, Год журнала: 2023, Номер 233, С. 112231 - 112231
Опубликована: Авг. 9, 2023
Bacterial infection continues to be one of the biggest threats human health. The therapeutic effect is significantly reduced as a result development super-bacteria-resistant bacteria due overuse antibiotics for conventional antimicrobial treatment. emergence drug-resistant makes it necessary develop new treatments. Following successful application photothermal therapy in field oncology treatment, more and researchers are applying treatments achieving important results, especially treatment bacterial infections. As non-invasive anti-infection method, has advantages broad-spectrum properties, short period, low systemic impact. In PTT, efficacy strongly depends on different laser properties choice agents (PTAs). purpose this review discuss most recent developments nanomaterials that antibacterial. We will delve into principles spectrum PTAs provide summary current synthesis, classification, structural features, physicochemical antibacterial performance research. challenges future prospects enhanced cytotoxicity investigated.
Язык: Английский
Процитировано
84Carbohydrate Polymers, Год журнала: 2022, Номер 299, С. 120228 - 120228
Опубликована: Окт. 14, 2022
Язык: Английский
Процитировано
81Bioactive Materials, Год журнала: 2022, Номер 18, С. 421 - 432
Опубликована: Март 29, 2022
Язык: Английский
Процитировано
75ACS Applied Bio Materials, Год журнала: 2022, Номер 5(2), С. 366 - 393
Опубликована: Янв. 24, 2022
Bacterial resistance caused by the overuse of antibiotics and shelter biofilms has evolved into a global health crisis, which drives researchers to continuously explore antimicrobial molecules strategies fight against drug-resistant bacteria biofilm-associated infections. Cationic peptides (AMPs) are considered be category potential alternative for owing their excellent bactericidal potency lesser likelihood inducing drug through distinctive mechanisms. In this review, hitherto reported plentiful action modes AMPs systematically classified 15 types three categories (membrane destructive, nondestructive membrane disturbance, intracellular targeting mechanisms). Besides natural AMPs, cationic polypeptides, synthetic polymers, biopolymers enable achieve tunable properties optimizing structures. Subsequently, applications these agents at biointerface as contact-active surface coatings multifunctional wound dressings also emphasized here. At last, we provide our perspectives on development clinically significant antimicrobials related challenges in translation materials.
Язык: Английский
Процитировано
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