Advanced Materials, Год журнала: 2024, Номер unknown
Опубликована: Сен. 12, 2024
Abstract Proteins have emerged as promising therapeutics in oncology due to their great specificity. Many treatment strategies are developed based on protein biologics, such immunotherapy, starvation therapy, and pro‐apoptosis while some biologics entered the clinics. However, clinical translation is severely impeded by instability, short circulation time, poor transmembrane transportation, immunogenicity. Micro‐ nano‐particles‐based drug delivery platforms designed solve those problems enhance therapeutic efficacy. This review first summarizes different types of proteins research stages, highlighting administration limitations. Next, various micro‐ nano‐particles described demonstrate how they can overcome The potential then explored efficacy combinational therapies. Finally, challenges future directions carriers discussed for optimized delivery.
Язык: Английский