Antibiotic Use in Livestock and Residues in Food—A Public Health Threat: A Review

Foods, Год журнала: 2022, Номер 11(10), С. 1430 - 1430

Опубликована: Май 16, 2022

The usage of antibiotics has been, and remains, a topic utmost importance; on the one hand, for animal breeders, other food safety. Although many countries have established strict rules using in husbandry industry, their misuse irregularities compliance with withdrawal periods are still identified. In addition to animal-origin foods that may cause antibiotic residue problems, more non-animal-origin this type non-compliance context, we aim summarize available information regarding presence residues products, obtained various parts world, as well impact consumption consumer health. We also present methods analysis currently used determine food, characterized by speed obtaining results or possibility identifying very small amounts residues.

Язык: Английский

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Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants

Chemical Reviews, Год журнала: 2021, Номер 122(10), С. 10036 - 10086

Опубликована: Дек. 8, 2021

Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for supporting integrity function regulating intercellular communication. These biomaterials also of significant interest to production biofuels development antimicrobial treatment. Solid-state nuclear magnetic resonance (ssNMR) magic-angle spinning-dynamic polarization (MAS-DNP) uniquely powerful understanding conformational structure, dynamical characteristics, supramolecular assemblies carbohydrates other biomolecules in ECMs. This review highlights recent high-resolution investigations intact ECMs native cells many organisms spanning across plants, bacteria, fungi, algae. We spotlight structural principles identified ECMs, discuss current technical limitation underexplored biochemical topics, point out promising opportunities enabled by advances rapidly evolving ssNMR technology.

Язык: Английский

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New insights in improving sustainability in meat production: opportunities and challenges

Critical Reviews in Food Science and Nutrition, Год журнала: 2022, Номер 63(33), С. 11830 - 11858

Опубликована: Июль 12, 2022

Treating livestock as senseless production machines has led to rampant depletion of natural resources, enhanced greenhouse gas emissions, gross animal welfare violations, and other ethical issues. It essentially instigated constant scrutiny conventional meat by various experts scientists. Sustainably in the sector is a big challenge which requires multifaced holistic approach. Novel tools like digitalization farming system market, precision farming, application remote sensing artificial intelligence manage environmental impact/GHG emission, can help attaining sustainability this sector. Further, improving nutrient use efficiency recycling feed through integration with agroecology industrial ecology, individual herd health ensuring proper biosecurity measures selective breeding, mitigating stress during are also key elements achieving production. In addition, bears direct relationship social dimensions such non-market attributes, balance between demand consumption, market policy failures. The present review critically examines aspects that significantly impact

Язык: Английский

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Potential Causes of Spread of Antimicrobial Resistance and Preventive Measures in One Health Perspective-A Review

Infection and Drug Resistance, Год журнала: 2023, Номер Volume 16, С. 7515 - 7545

Опубликована: Дек. 1, 2023

Abstract: Antimicrobial resistance, referring to microorganisms' capability subsist and proliferate even when there are antimicrobials is a foremost threat public health globally. The appearance of antimicrobial resistance can be ascribed anthropological, animal, environmental factors. Human-related causes include overuse misuse in medicine, antibiotic-containing cosmetics biocides utilization, inadequate sanitation hygiene settings. Prophylactic therapeutic overuse, using as feed additives, microbes resistant antibiotics genes animal excreta, residue found animal-origin food excreta animals related contributive factors for the antibiotic emergence spread. Environmental including naturally existing genes, improper disposal unused antimicrobials, contamination from waste settings, farms, pharmaceutical industries, use agricultural chemicals facilitatet its Wildlife has plausible role Adopting one-health approach involving properly humans, improving spaces implementing coordinated governmental regulations crucial combating resistance. Collaborative cooperative involvement stakeholders public, veterinary ecological sectors circumvent problem effectively. Keywords: one health, gene, environment, wildlife

Язык: Английский

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Antibiotic resistant bacteria in food systems: Current status, resistance mechanisms, and mitigation strategies

Agriculture Communications, Год журнала: 2024, Номер 2(1), С. 100027 - 100027

Опубликована: Фев. 3, 2024

The pervasive use of antibiotics in agriculture and animal husbandry has raised a significant concern—residual antibiotic contamination food, which contributes to the natural evolution resistance pathogenic microbial strains. emergence communities poses global threat food safety security. Recently, situation been exacerbated by discovery novel strains resistant bacteria (ARB) plant- animal-derived foods. These microbes can enter human body through direct contact with affected animals or consumption contaminated In this review, we explore prevalence contaminants at various locations around world, delve into molecular mechanisms behind acquisition antimicrobial resistance, examine current strategies employed mitigate spread pathogens, discuss emerging technologies aimed halting trend that projects 10 million annual deaths 2050 as result ARB agriculture. Genetic processes, including mutations, efflux pump activity, horizontal gene transfer, play crucial roles widespread distribution community. Effectively addressing requires development methodologies rapidly detect supply chain. Therefore, several established rapid diagnostic techniques such Quick, Easy, Cheap, Effective, Rugged, Safe (QuEChERS) methodology, aptasensors, fluorescence-based Metal Organic Frameworks. Additionally, innovative fight nano-antibiotics, antibiotics, synthetic biology, bacteriophages, predator bacteria. Here, propose omics biochar potential tools for combating ARB. We anticipate review article will serve valuable resource future research, particularly designed not only suppress activities genes but also potentially reverse are already communities.

Язык: Английский

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An Overview of the Recent Advances in Antimicrobial Resistance

Microorganisms, Год журнала: 2024, Номер 12(9), С. 1920 - 1920

Опубликована: Сен. 21, 2024

Antimicrobial resistance (AMR), frequently considered a major global public health threat, requires comprehensive understanding of its emergence, mechanisms, advances, and implications. AMR’s epidemiological landscape is characterized by widespread prevalence constantly evolving patterns, with multidrug-resistant organisms (MDROs) creating new challenges every day. The most common mechanisms underlying AMR (i.e., genetic mutations, horizontal gene transfer, selective pressure) contribute to the emergence dissemination resistant strains. Therefore, mitigation strategies (e.g., antibiotic stewardship programs—ASPs—and infection prevention control strategies—IPCs) emphasize importance responsible antimicrobial use surveillance. A One Health approach interconnectedness human, animal, environmental health) highlights necessity for interdisciplinary collaboration holistic in combating AMR. Advancements novel therapeutics alternative agents vaccines) offer promising avenues addressing challenges. Policy interventions at international national levels also promote ASPs aiming regulate use. Despite all observed progress, remains pressing concern, demanding sustained efforts address emerging threats sustainability. Future research must prioritize innovative approaches complex socioecological dynamics This manuscript resource researchers, policymakers, healthcare professionals seeking navigate develop effective mitigation.

Язык: Английский

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Antimicrobial Resistance in Escherichia coli Strains Isolated from Humans and Pet Animals

Antibiotics, Год журнала: 2021, Номер 10(1), С. 69 - 69

Опубликована: Янв. 13, 2021

Throughout scientific literature, we can find evidence that antimicrobial resistance has become a big problem in the recent years on global scale. Public healthcare systems all over world are faced with great challenge this respect. Obviously, there many bacteria cause infections humans and animals alike, but somehow it seems greatest threat nowadays comes from Enterobacteriaceae members, especially Escherichia coli. Namely, witnesses to fact these developed fight off antibiotics strongest most diverse Enterobacteriaceae. Our advantage is understanding antibiotics, so help us understand connection between microorganisms occurrence of antibiotic-resistance both their pets. Furthermore, unfavorable conditions related ease E. coli transmission via fecal–oral route among humans, environmental sources, only add problem. For above stated reasons, evident epidemiology strains mechanisms they have time extremely significant topics findings area will be vital importance against caused by bacteria.

Язык: Английский

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Antibacterial and antioxidant properties of humic substances from composted agricultural biomasses

Chemical and Biological Technologies in Agriculture, Год журнала: 2022, Номер 9(1)

Опубликована: Апрель 4, 2022

Abstract Background Bioactive components isolated from composted agricultural biomasses have been receiving progressive attention, because they may improve the antibiotic susceptibility of drug resistant bacterial strains. Here, three different humic substances (HS) were artichoke (HS-CYN) and pepper (HS-PEP) wastes, coffee grounds (HS-COF), characterized by infrared spectrometry, NMR spectroscopy, thermochemolysis–GC/MS, high-performance size-exclusion chromatography. The antibacterial activity HS was evaluated against some pathogenic strains, while their bioactivity determined a germination assay on basil ( Red – Violet variety) seeds. Results HS-CYN HS-PEP exhibited largest antioxidant most significant antimicrobial capacity gram-positive such as Staphylococcus aureus Enterococcus faecalis . same increase both root epicotyls in seed experiments. related not only to specific molecular composition but also conformational stability suprastructures. Specifically, greatest bioactive properties abundance hydrophobic aromatic phenolic more rigid arrangement, that, turn, appeared be small fragmentation degree lignin structures. Conclusions Our results showed that extraction green composts sustainable eco-compatible way valorise byproducts. indeed exploited substrates produce novel materials plant productivity for medical applications. Graphical

Язык: Английский

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Perspectives on systematic generation of antibiotic resistance with special emphasis on modern antibiotics

Total Environment Research Themes, Год журнала: 2023, Номер 8, С. 100068 - 100068

Опубликована: Июль 13, 2023

Antibiotics, considered a "wonder medication" in the 20th century, have been exploited to such an extent that bacteria developed resistance against them giving rise highly resistant superbugs, which are able survive presence of medicine is designed stop from growing. The study elucidates classification and molecular mechanisms methods employed by different generations antibiotics with their classes, examples strains. overuse, misuse underuse several antibiotic classes improper disposal/treatment various industries including agriculture, poultry, veterinary healthcare has led generation many species at higher rate. causes, drivers, consequences, environmental impact also addressed. This major global concern amid recent infectious diseases caused bacterial pathogens calls for effective, newer better alternative treatments. If we fail combat resistance, death tolls due small infections would further lead social, economic, medical losses. paper highlights pressing need curb overuse prevent advocates regulation, awareness programs about AMR barriers discovery.

Язык: Английский

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Optical nanosensors based on noble metal nanoclusters for detecting food contaminants: A review

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2024, Номер 23(1)

Опубликована: Янв. 1, 2024

Abstract Food contaminants present a significant threat to public health. In response escalating global concerns regarding food safety, there is growing demand for straightforward, rapid, and sensitive detection technologies. Noble metal nanoclusters (NMNCs) have garnered considerable attention due their superior attributes compared other optical materials. These include high catalytic activity, excellent biocompatibility, outstanding photoluminescence properties. features render NMNCs promising candidates crafting nanosensors contaminant detection, offering the potential development of uncomplicated, swift, sensitive, user‐friendly, cost‐effective approaches. This review investigates based on NMNCs, including synthesis methodologies sensing strategies, applications in detecting contaminants. Furthermore, it involves comparative assessment performance. Ultimately, this paper imparts fresh perspectives forthcoming challenges. Hitherto, (particularly fluorescent) founded demonstrated exceptional capabilities realm detection. To enhance performance, future research should prioritize atomically precise synthesis, augmentation activity properties, high‐throughput multimode sensing, integration with microfluidic devices, optimization storage, shelf life, transportation conditions.

Язык: Английский

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