Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Дек. 30, 2024
Medical
datasets
are
vital
for
advancing
Artificial
Intelligence
(AI)
in
healthcare.
Yet
biases
these
on
which
deep-learning
models
trained
can
compromise
reliability.
This
study
investigates
stemming
from
dataset-creation
practices.
Drawing
existing
guidelines,
we
first
developed
a
BEAMRAD
tool
to
assess
the
documentation
of
public
Magnetic
Resonance
Imaging
(MRI);
Color
Fundus
Photography
(CFP),
and
Electrocardiogram
(ECG)
datasets.
In
doing
so,
provide
an
overview
that
may
emerge
due
inadequate
dataset
documentation.
Second,
examine
current
state
medical
images
signal
data.
Our
research
reveals
there
is
substantial
variance
image
datasets,
even
though
guidelines
have
been
imaging.
indicates
subject
individual
discretionary
decisions.
Furthermore,
find
aspects
such
as
hardware
data
acquisition
details
commonly
documented,
while
information
regarding
annotation
practices,
error
quantification,
or
limitations
not
consistently
reported.
risks
having
considerable
implications
abilities
users
detect
potential
sources
bias
through
respective
develop
reliable
robust
be
adapted
clinical
practice.
BioMedical Engineering OnLine,
Год журнала:
2024,
Номер
23(1)
Опубликована: Июнь 8, 2024
Abstract
Accurate
segmentation
of
multiple
organs
in
the
head,
neck,
chest,
and
abdomen
from
medical
images
is
an
essential
step
computer-aided
diagnosis,
surgical
navigation,
radiation
therapy.
In
past
few
years,
with
a
data-driven
feature
extraction
approach
end-to-end
training,
automatic
deep
learning-based
multi-organ
methods
have
far
outperformed
traditional
become
new
research
topic.
This
review
systematically
summarizes
latest
this
field.
We
searched
Google
Scholar
for
papers
published
January
1,
2016
to
December
31,
2023,
using
keywords
“multi-organ
segmentation”
“deep
learning”,
resulting
327
papers.
followed
PRISMA
guidelines
paper
selection,
195
studies
were
deemed
be
within
scope
review.
summarized
two
main
aspects
involved
segmentation:
datasets
methods.
Regarding
datasets,
we
provided
overview
existing
public
conducted
in-depth
analysis.
Concerning
methods,
categorized
approaches
into
three
major
classes:
fully
supervised,
weakly
supervised
semi-supervised,
based
on
whether
they
require
complete
label
information.
achievements
these
terms
accuracy.
discussion
conclusion
section,
outlined
current
trends
segmentation.
Radiotherapy and Oncology,
Год журнала:
2024,
Номер
198, С. 110410 - 110410
Опубликована: Июнь 24, 2024
To
promote
the
development
of
auto-segmentation
methods
for
head
and
neck
(HaN)
radiation
treatment
(RT)
planning
that
exploit
information
computed
tomography
(CT)
magnetic
resonance
(MR)
imaging
modalities,
we
organized
HaN-Seg:
The
Head
Neck
Organ-at-Risk
CT
MR
Segmentation
Challenge.
challenge
task
was
to
automatically
segment
30
organs-at-risk
(OARs)
HaN
region
in
14
withheld
test
cases
given
availability
42
publicly
available
training
cases.
Each
case
consisted
one
contrast-enhanced
T1-weighted
image
same
patient,
with
up
corresponding
reference
OAR
delineation
masks.
performance
evaluated
terms
Dice
similarity
coefficient
(DSC)
95-percentile
Hausdorff
distance
(HD95),
statistical
ranking
applied
each
metric
by
pairwise
comparison
submitted
using
Wilcoxon
signed-rank
test.
While
23
teams
registered
challenge,
only
seven
their
final
phase.
top-performing
team
achieved
a
DSC
76.9
%
HD95
3.5
mm.
All
participating
utilized
architectures
based
on
U-Net,
winning
leveraging
rigid
registration
combined
network
entry-level
concatenation
both
modalities.
This
simulated
real-world
clinical
scenario
providing
non-registered
images
varying
fields-of-view
voxel
sizes.
Remarkably,
segmentation
surpassing
inter-observer
agreement
dataset.
These
results
set
benchmark
future
research
this
dataset
paired
multi-modal
general.
Medical Physics,
Год журнала:
2024,
Номер
51(3), С. 2175 - 2186
Опубликована: Янв. 17, 2024
Abstract
Background
Accurate
and
consistent
contouring
of
organs‐at‐risk
(OARs)
from
medical
images
is
a
key
step
radiotherapy
(RT)
cancer
treatment
planning.
Most
approaches
rely
on
computed
tomography
(CT)
images,
but
the
integration
complementary
magnetic
resonance
(MR)
modality
highly
recommended,
especially
perspective
OAR
contouring,
synthetic
CT
MR
image
generation
for
MR‐only
RT,
MR‐guided
RT.
Although
has
been
recognized
as
valuable
OARs
in
head
neck
(HaN)
region,
accuracy
consistency
resulting
contours
have
not
yet
objectively
evaluated.
Purpose
To
analyze
interobserver
intermodality
variability
HaN
performed
by
observers
with
different
level
experience
same
patients.
Methods
In
final
cohort
27
patients,
up
to
31
were
obtained
radiation
oncology
resident
(junior
observer,
JO)
board‐certified
oncologist
(senior
SO).
The
then
evaluated
terms
variability,
characterized
agreement
among
(JO
SO)
when
selected
(CT
or
MR),
modalities
MR)
contoured
observer
SO),
both
Dice
coefficient
(DC)
95‐percentile
Hausdorff
distance
(HD
).
Results
mean
(±standard
deviation)
was
69.0
±
20.2%
5.1
4.1
mm,
while
61.6
19.0%
6.1
4.3
mm
DC
HD
,
respectively,
across
all
OARs.
Statistically
significant
differences
only
found
specific
registration
resulted
target
error
1.7
0.5
which
considered
valid
analysis
variability.
Conclusions
was,
general,
similar
modalities,
did
considerably
affect
performance.
However,
results
indicate
that
an
difficult
contour
regardless
whether
it
image,
may
be
important
factor
are
deemed
contour.
Several
can
also
attributed
adherence
guidelines,
poor
visibility
without
distinctive
boundaries
either
images.
considerable
observed
OARs,
concluded
almost
degree
modality,
works
favor
Physics in Medicine and Biology,
Год журнала:
2024,
Номер
69(3), С. 035008 - 035008
Опубликована: Янв. 2, 2024
The
field
of
radiotherapy
is
highly
marked
by
the
lack
datasets
even
with
availability
public
datasets.
Our
study
uses
a
very
limited
dataset
to
provide
insights
on
essential
parameters
needed
automatically
and
accurately
segment
individual
bones
planning
CT
images
head
neck
cancer
patients.
Cancers,
Год журнала:
2024,
Номер
16(2), С. 415 - 415
Опубликована: Янв. 18, 2024
The
delineation
of
the
clinical
target
volumes
(CTVs)
for
radiation
therapy
is
time-consuming,
requires
intensive
training
and
shows
high
inter-observer
variability.
Supervised
deep-learning
methods
depend
heavily
on
consistent
data;
thus,
State-of-the-Art
research
focuses
making
CTV
labels
more
homogeneous
strictly
bounding
them
to
current
standards.
International
consensus
expert
guidelines
standardize
by
conditioning
extension
volume
surrounding
anatomical
structures.
Training
strategies
that
directly
follow
construction
rules
given
in
or
possibility
quantifying
conformance
manually
drawn
contours
are
still
missing.
Seventy-one
structures
relevant
head-
neck-cancer
patients,
according
guidelines,
were
segmented
104
computed
tomography
scans,
assess
automating
their
segmentation
deep
learning
methods.
All
71
subdivided
into
three
subsets
non-overlapping
structures,
a
3D
nnU-Net
model
with
five-fold
cross-validation
was
trained
each
subset,
automatically
segment
planning
scans.
We
report
DICE,
Hausdorff
distance
surface
DICE
+
5
most
which
no
previous
accuracies
have
been
reported.
For
those
prediction
values
reported,
our
accuracy
matched
exceeded
reported
values.
predictions
from
models
always
better
than
predicted
TotalSegmentator.
sDICE
2
mm
margin
larger
80%
almost
all
Individual
decreased
analyzed
discussed
respect
impact
following
guidelines.
No
deviation
expected
affect
rule-based
automation
delineation.
Medical Physics,
Год журнала:
2024,
Номер
51(7), С. 4767 - 4777
Опубликована: Фев. 20, 2024
Abstract
Background
Auto‐segmentation
of
organs‐at‐risk
(OARs)
in
the
head
and
neck
(HN)
on
computed
tomography
(CT)
images
is
a
time‐consuming
component
radiation
therapy
pipeline
that
suffers
from
inter‐observer
variability.
Deep
learning
(DL)
has
shown
state‐of‐the‐art
results
CT
auto‐segmentation,
with
larger
more
diverse
datasets
showing
better
segmentation
performance.
Institutional
auto‐segmentation
have
been
small
historically
(n
<
50)
due
to
time
required
for
manual
curation
anatomical
labels.
Recently,
large
public
>
1000
aggregated)
become
available
through
online
repositories
such
as
The
Cancer
Imaging
Archive.
Transfer
technique
applied
when
training
samples
are
scarce,
but
dataset
closely
related
domain
available.
Purpose
purpose
this
study
was
investigate
whether
could
be
used
place
an
institutional
500),
or
augment
performance
via
transfer
learning,
building
HN
OAR
models
use.
Methods
were
trained
(public
models)
smaller
(institutional
models).
fine‐tuned
using
(transfer
We
assessed
both
model
generalizability
by
comparison
models.
Additionally,
effect
size
investigated.
All
DL
high‐resolution,
two‐stage
architecture
based
popular
3D
U‐Net.
Model
evaluated
five
geometric
measures:
dice
similarity
coefficient
(DSC),
surface
DSC,
95
th
percentile
Hausdorff
distance,
mean
distance
(MSD),
added
path
length.
Results
For
subset
OARs
(left/right
optic
nerve,
spinal
cord,
left
submandibular),
performed
significantly
(
p
0.05)
than,
showed
no
significant
difference
to,
under
most
metrics
examined.
remaining
OARs,
inferior
models,
although
differences
(DSC
≤
0.03,
MSD
0.5
mm)
seven
(brainstem,
left/right
lens,
parotid,
mandible,
right
submandibular).
than
cord)
margin
improvement
0.02,
0.4
mm).
When
numbers
limited,
outperformed
Conclusion
Training
data
alone
suitable
number
OARs.
Using
only
incurred
deficit
other
compared
alone,
may
preferable
over
dataset.
available,
pretrained
provided
modest
several
model,
beneficial
Bioengineering,
Год журнала:
2024,
Номер
11(3), С. 214 - 214
Опубликована: Фев. 24, 2024
The
delineation
of
parotid
glands
in
head
and
neck
(HN)
carcinoma
is
critical
to
assess
radiotherapy
(RT)
planning.
Segmentation
processes
ensure
precise
target
position
treatment
precision,
facilitate
monitoring
anatomical
changes,
enable
plan
adaptation,
enhance
overall
patient
safety.
In
this
context,
artificial
intelligence
(AI)
deep
learning
(DL)
have
proven
exceedingly
effective
precisely
outlining
tumor
tissues
and,
by
extension,
the
organs
at
risk.
This
paper
introduces
a
DL
framework
using
AttentionUNet
neural
network
for
automatic
gland
segmentation
HN
cancer.
Extensive
evaluation
model
performed
two
public
one
private
dataset,
while
accuracy
compared
with
other
state-of-the-art
schemas.
To
replanning
necessity
during
treatment,
an
additional
registration
method
implemented
on
output,
aligning
images
different
modalities
(Computed
Tomography
(CT)
Cone
Beam
CT
(CBCT)).
outperforms
similar
methods
(Dice
Similarity
Coefficient:
82.65%
±
1.03,
Hausdorff
Distance:
6.24
mm
2.47),
confirming
its
effectiveness.
Moreover,
subsequent
procedure
displays
increased
similarity,
providing
insights
into
effects
RT
procedures
planning
adaptations.
implementation
proposed
indicates
effectiveness
not
only
structures,
but
also
provision
information
adaptive
support.