ACS Chemical Neuroscience,
Год журнала:
2024,
Номер
15(3), С. 408 - 446
Опубликована: Янв. 12, 2024
Aging
is
typified
by
a
gradual
loss
of
physiological
fitness
and
accumulation
cellular
damage,
leading
to
deteriorated
functions
enhanced
vulnerability
diseases.
Antiaging
research
has
long
history
throughout
civilization,
with
many
efforts
put
forth
understand
prevent
the
effects
aging.
Multiple
strategies
aiming
promote
healthy
aging
extend
lifespan
have
been
developed
including
lifestyle
adjustments,
medical
treatments,
social
programs.
A
multitude
antiaging
medicines
remedies
also
explored.
Here,
we
use
data
from
CAS
Content
Collection
analyze
publication
landscape
recent
related
treatments.
We
review
advances
delineate
trends
in
headway
knowledge
practice
across
time,
geography,
development
pipelines.
further
assess
state-of-the-art
approaches
explore
their
correlations
age-related
The
drugs
outlined
Well-recognized
novel,
currently
evaluated
agents
summarized.
Finally,
clinical
applications
products
objective
this
summarize
current
on
preventive
treatment
field
aging,
outline
challenges
evaluate
growth
opportunities,
order
solve
problems
that
remain.
Polymers,
Год журнала:
2021,
Номер
13(23), С. 4146 - 4146
Опубликована: Ноя. 27, 2021
Cancer
is
a
disease
that
has
resulted
in
millions
of
deaths
worldwide.
The
current
conventional
therapies
utilized
for
the
treatment
cancer
have
detrimental
side
effects.
This
led
scientific
researchers
to
explore
new
therapeutic
avenues
with
an
improved
benefit
risk
profile.
Researchers
found
nanoparticles,
particles
between
1
and
100
nm
range,
be
encouraging
tools
area
cancer.
Magnetic
nanoparticles
are
one
many
available
at
present.
increasingly
been
receiving
considerable
amount
attention
recent
years
owing
their
unique
magnetic
properties,
among
others.
can
controlled
by
external
field,
signifying
ability
site
specific.
most
popular
approaches
synthesis
co-precipitation,
thermal
decomposition,
hydrothermal,
polyol
synthesis.
functionalization
essential
as
it
significantly
increases
biocompatibility.
agents
comprised
polymers.
will
further
explored
this
review.
biomedical
applications
investigated
review
drug
delivery,
hyperthermia,
diagnosis.
diagnosis
aspect
focuses
on
utilization
contrast
resonance
imaging.
Clinical
trials
toxicology
studies
relating
application
also
discussed
ACS Applied Bio Materials,
Год журнала:
2022,
Номер
5(6), С. 2431 - 2460
Опубликована: Май 18, 2022
The
COVID-19
pandemic
caused
by
the
SARS-CoV-2,
a
ribonucleic
acid
(RNA)
virus
that
emerged
less
than
two
years
ago
but
has
nearly
6.1
million
deaths
to
date.
Recently
developed
variants
of
SARS-CoV-2
have
been
shown
be
more
potent
and
expanded
at
faster
rate.
Until
now,
there
is
no
specific
effective
treatment
for
in
terms
reliable
sustainable
recovery.
Precaution,
prevention,
vaccinations
are
only
ways
keep
situation
under
control.
Medical
scientific
professionals
now
focusing
on
repurposing
previous
technology
trying
develop
fruitful
methodologies
detect
presence
viruses,
treat
patients,
precautionary
items,
vaccine
developments.
Nanomedicine
or
nanobased
platforms
can
play
crucial
role
these
fronts.
Researchers
working
many
approaches
nanosized
particles
combat
SARS-CoV-2.
platform
extremely
diverse
(i.e.,
mark
personal
protective
suit,
rapid
diagnostic
tool
targeted
treatment,
developments).
Although
theoretical
possibilities
until
an
inadequate
number
research
targeting
explore
such
scenarios.
This
unique
mini-review
aims
compile
elaborate
recent
advances
from
diagnostics,
developments
against
associated
challenges.
Encyclopedia,
Год журнала:
2022,
Номер
2(4), С. 1811 - 1828
Опубликована: Ноя. 14, 2022
Magnetic
nanoparticles
(MNPs)
have
great
potential
in
various
areas
such
as
medicine,
cancer
therapy
and
diagnostics,
biosensing,
material
science.
In
particular,
magnetite
(Fe3O4)
are
extensively
used
for
numerous
bioapplications
due
to
their
biocompatibility,
high
saturation
magnetization,
chemical
stability,
large
surface
area,
easy
functionalization.
This
paper
describes
magnetic
nanoparticle
physical
biological
properties,
emphasizing
synthesis
approaches,
toxicity,
biomedical
applications,
focusing
on
the
most
recent
advancements
of
therapy,
theranostics,
separation,
biosensing.
Pharmaceutics,
Год журнала:
2023,
Номер
15(7), С. 1872 - 1872
Опубликована: Июль 3, 2023
With
the
predicted
rise
in
incidence
of
cancer,
there
is
an
ever-growing
need
for
new
cancer
treatment
strategies.
Recently,
magnetic
nanoparticles
have
stood
out
as
promising
nanostructures
imaging
and
drug
delivery
systems
they
possess
unique
properties.
Moreover,
nanomaterials
functionalized
with
other
compounds
can
lead
to
multicomponent
innovative
structures
synergetic
performance.
The
incorporation
chemotherapeutic
drugs
or
RNA
represents
a
alternative
that
increase
efficiency
reduce
side
effects
anticancer
therapy.
This
review
presents
critical
overview
recent
literature
concerning
advancements
field
used
delivery,
focus
on
their
classification,
characteristics,
synthesis
functionalization
methods,
limitations,
examples
incorporating
chemotherapeutics
RNA.
