Nutrition Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 2, 2024
Abstract
Time-restricted
feeding
(TRF)
is
a
lifestyle
intervention
that
aims
to
maintain
consistent
daily
cycle
of
and
fasting
support
robust
circadian
rhythms.
Recently,
it
has
gained
scientific,
medical,
public
attention
due
its
potential
enhance
body
composition,
extend
lifespan,
improve
overall
health,
as
well
induce
autophagy
alleviate
symptoms
diseases
like
cardiovascular
diseases,
type
2
diabetes,
neurodegenerative
cancer,
ischemic
injury.
However,
there
still
considerable
debate
on
the
primary
factors
contribute
health
benefits
TRF.
Despite
not
imposing
strict
limitations
calorie
intake,
TRF
consistently
led
reductions
in
intake.
Therefore,
while
some
studies
suggest
are
primarily
caloric
restriction
(CR),
others
argue
key
advantages
arise
only
from
CR
but
also
duration
fasting,
timing
period,
alignment
with
To
elucidate
roles
mechanisms
beyond
CR,
this
review
incorporates
did
use
equivalent
energy
intake
which
addresses
previous
lack
comprehensive
research
without
provides
framework
for
future
directions.
Annals of Internal Medicine,
Год журнала:
2023,
Номер
176(7), С. 885 - 895
Опубликована: Июнь 26, 2023
Time-restricted
eating
(TRE),
without
calorie
counting,
has
become
a
popular
weight
loss
strategy,
yet
long-term
randomized
trials
evaluating
its
efficacy
are
limited.
The Journal of Clinical Endocrinology & Metabolism,
Год журнала:
2023,
Номер
108(7), С. 1824 - 1834
Опубликована: Янв. 26, 2023
Abstract
Context
It
remains
controversial
whether
the
choice
of
daily
eating
window
early
or
later
in
time-restricted
(TRE)
intervention
(early
TRE)
has
different
effects
on
weight
loss
and
metabolic
health.
Objective
A
network
meta-analysis
was
performed
to
evaluate
efficacy
between
TRE
adults
with
obesity
overweight.
Methods
We
searched
PubMed,
Embase,
Web
Science,
Cochrane
Library
for
randomized
controlled
trials
(RCTs)
published
until
October
16,
2022.
conducted
a
body
parameters,
including
glycemic
metabolism,
blood
pressure,
lipid
profiles.
Results
Twelve
RCTs
730
obese
overweight
were
included
this
meta-analysis.
Early
both
elicited
moderate
reductions
insulin
resistance
(IR)
(homeostasis
model
assessment
IR)
when
compared
non-TRE.
Interestingly,
showed
more
effectiveness
than
improving
IR
vs
TRE:
−0.44;
95%
CI,
−0.86
−0.02;
P
<
.05),
whereas
no
statistically
significant
difference
detected
−0.31
kg;
−1.15
0.53
>.05).
In
addition,
rather
benefits
metabolism
pressure
No
differences
observed
fasting
glucose,
Conclusion
This
suggests
that
people
may
choose
effective
management
benefits.
Nevertheless,
further
large-scale
are
warranted
verify
our
findings.
EClinicalMedicine,
Год журнала:
2024,
Номер
70, С. 102519 - 102519
Опубликована: Март 11, 2024
Benefits
of
Intermittent
fasting
(IF)
on
health-related
outcomes
have
been
found
in
a
range
randomised
controlled
trials
(RCTs).
Our
umbrella
review
aimed
to
systematically
analyze
and
synthesize
the
available
causal
evidence
IF
its
impact
specific
while
evaluating
quality.
Alimentary Pharmacology & Therapeutics,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 28, 2025
ABSTRACT
Background
The
Mediterranean
diet
(MD)
is
considered
the
best
dietary
approach
for
patients
with
metabolic
dysfunction‐associated
steatotic
liver
disease
(MASLD).
Recently,
time‐restricted
feeding
(TRF)
has
gained
attention
its
lifestyle
compatibility
and
health
benefits.
Aims
This
study
aimed
to
compare
effects
of
a
hypocaloric
MD
10‐h
TRF
protocol
an
unrestricted
in
MASLD
overweight/obesity
evaluate
differences
between
early
late
TRF.
Methods
12‐week
randomised
controlled
trial
consisted
three
groups,
all
following
Mediterranean‐type
diet.
control
group
had
no
eating
time
restrictions.
(eTRF)
(lTRF)
groups
window,
from
8
AM
6
PM
12
10
PM,
respectively.
Various
parameters
were
measured.
Compliance
was
tracked
via
food
diaries,
8‐week
follow‐up
occurred
post‐intervention.
Results
Fifty‐nine
individuals
(27
males;
52.9
years;
body
mass
index
32.1
kg/m
2
)
completed
(control,
n
=
19;
eTRF,
20;
lTRF,
20).
All
showed
significant
reductions
weight,
anthropometry
blood
pressure.
Glycated
haemoglobin
A
1c
insulin
resistance,
as
measured
by
Matsuda
index,
homeostatic
model
assessment
resistance
fasting
glucose‐to‐insulin
ratio,
improved
eTRF
at
weeks.
Conclusions
corroborates
efficacy
ameliorating
cardiometabolic
risk
factors
such
weight
pressure
patients.
combination
may
improve
glycaemic
(NCT05866744).
Trial
Registration
registered
clinicaltrials.gov
(NCT05866744)
Physiological Reviews,
Год журнала:
2022,
Номер
102(4), С. 1991 - 2034
Опубликована: Июль 14, 2022
Time-restricted
eating
(TRE)
is
a
dietary
intervention
that
limits
food
consumption
to
specific
time
window
each
day.
The
effect
of
TRE
on
body
weight
and
physiological
functions
has
been
extensively
studied
in
rodent
models,
which
have
shown
considerable
therapeutic
effects
important
interactions
among
eating,
circadian
biology,
metabolic
homeostasis.
In
contrast,
it
difficult
make
firm
conclusions
regarding
the
people
because
heterogeneity
results,
regimens,
study
populations.
this
review,
we
1)
provide
background
history
meal
normal
physiology
fasting;
2)
discuss
interaction
between
molecular
metabolism
TRE;
3)
integrate
results
preclinical
clinical
studies
evaluated
functions;
4)
summarize
other
time-related
interventions
people;
identify
current
gaps
knowledge
framework
for
future
research
directions.
Frontiers in Nutrition,
Год журнала:
2023,
Номер
10
Опубликована: Фев. 16, 2023
The
number
of
people
suffering
from
overweight
or
obesity
has
been
steadily
increasing
in
recent
years.
As
a
new
form
diet,
the
efficacy
time-restricted
eating
(TRE)
remains
debatable.This
meta-analysis
quantified
effect
TRE
on
weight
change
and
other
physical
parameters
obese
adults.We
did
systematic
review
randomized
controlled
trials
(RCTs)
comparing
interventions
loss
metabolic
by
searching
PubMed,
Embase,
Cochrane
Central
Register
Controlled
Trials
to
identify
eligible
published
database
inception
up
until
23
August
2022.
risk
bias
was
assessed
using
Revised
risk-of-bias
tool
(ROB-2.0).
Meta-analysis
performed
Review
Manager
5.4.1
software.Nine
RCTs
with
665
individuals
(345
group
while
320
control
group)
were
included.
Results
indicated
that
had
greater
decrease
body
(-1.28
kg;
95%
CI
[-2.05,
-0.52],
p
=
0.001),
fat
mass
(-0.72
[-1.40,
-0.03],
0.04),
index
(-0.34
kg/m2;
[-0.64,
-0.04],
0.03)
diastolic
blood
pressure
(-2.26
mmHg
[-4.02,
-0.50],
0.01).
However,
demonstrated
there
no
significant
difference
between
lean
mass,
systolic
pressure,
waist
circumference,
fasting
glucose,
insulin,
homeostasis
model
assessment-insulin
resistance
(HOMA-IR),
total
cholesterol,
high-density
lipoprotein,
low-density
triglycerides.
Besides,
duration
study
daily
window
also
an
impact
change.TRE
associated
reductions
can
be
dietary
intervention
option
for
adults
obesity.
But
high-quality
longer
follow-ups
are
needed
draw
definitive
conclusions.
iScience,
Год журнала:
2024,
Номер
27(2), С. 109000 - 109000
Опубликована: Янв. 26, 2024
Time-restricted
eating
(TRE)
is
an
effective
way
to
lose
weight
and
improve
metabolic
health
in
animals.
Yet
whether
how
these
benefits
apply
humans
unclear.
This
systematic
review
meta-analysis
examined
the
effect
of
TRE
people
with
overweight
obesity
statuses.
The
results
showed
that
led
modest
loss,
lower
waist
circumference
energy
deficits.
also
improved
body
mass
index,
fat
mass,
lean
systolic
blood
pressure,
fasting
glucose
levels,
insulin
HbA1c%.
Subgroup
analysis
demonstrated
more
improvements
group
than
control
under
Annals of Internal Medicine,
Год журнала:
2024,
Номер
177(5), С. 549 - 558
Опубликована: Апрель 19, 2024
Time-restricted
eating
(TRE)
lowers
body
weight
in
many
studies.
Whether
TRE
induces
loss
independent
of
reductions
calorie
intake,
as
seen
rodent
studies,
is
unknown.
