Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106633 - 106633
Опубликована: Янв. 1, 2025
Язык: Английский
Advanced Industrial and Engineering Polymer Research, Год журнала: 2024, Номер unknown
Опубликована: Май 1, 2024
Bio-based polymers have garnered significant interest across the manufacturing industry, global economy, and various engineering disciplines such as packaging, tissue engineering, controlled drug delivery, wound dressing, textiles. In current era, bio-based polymers, notably polysaccharides, offer a promising platform for constructing intricate versatile structures in biomedical sector. These encompass applications regenerative medicine (TERM), delivery devices, coatings wearable sensors, thanks to their distinctive features inherent biocompatibility, flexibility, stretchability, mechanical strength, renewability, physiological activity, favorable biological environment. this review, we concise overview of diverse types polysaccharide-based composites, properties, interactions with specific cells tissues. The review encompasses recent progress scaffolds designed cartilage, skin, neural, vascular, cardiac, bone regeneration, employing both conventional modern techniques. Additionally, it delves into development other biodegradable including systems (DDSs), antibacterial on medical electronic devices healthcare Furthermore, also elucidates research directions future perspectives while emphasizing importance regulatory approvals commitment environmental sustainability. This well-organized critical is expected assist practitioners researchers gaining deeper understanding trends, challenges, potential solutions, thereby harnessing immense biomaterials system. utilization polysaccharides sector aligns principles nature, contributing reduction carbon dioxide emissions supporting Sustainable Development Goals United Nations.
Язык: Английский
Процитировано
17
Giant, Год журнала: 2024, Номер 19, С. 100301 - 100301
Опубликована: Июнь 6, 2024
The global community has encountered numerous challenges concerning environmental sustainability, encompassing issues like waste generation, depletion of natural resources, air pollution, and other threats to human well-being. Consequently, the pursuit an eco-friendly environment emerged as a critical concern in recent years. Polysaccharides, being biopolymers, have garnered significant attention owing their distinctive properties that make them versatile for various applications. Numerous sustainable environmentally friendly polysaccharides, such chitosan, cellulose, starch, hyaluronic acid, alginate, inulin, been identified. This article highlights characteristics renewable categorization, potential contribute sustainability. It introduces extraction methods aimed at minimizing chemical pollution. Through careful selection diverse polysaccharides application functionalization techniques, suggests possibility obtaining suitable superabsorbent hydrogels, appropriate nanocomposites, effective scaffolds. significance utilizing polysaccharide-based materials is explored detail, emphasizing exceptional properties. Additionally, discusses applications polymers, including agriculture, biomedicine, food packaging.
Язык: Английский
Процитировано
17
Sustainability, Год журнала: 2025, Номер 17(1), С. 335 - 335
Опубликована: Янв. 4, 2025
The sustainability of the planet is based on reducing use fossil fuels and greenhouse gas emissions. recovery biomass waste puts economically valuable materials into circulation, which can successfully replace would otherwise be sent to landfills. Based review several published works, we observe that referenced processes value or are not necessarily most profitable environmentally friendly. used methods valorize mainly researchers knowledge experience, neglecting some more appropriate developing technologies. valorization wastes should promote production products with highest added value, it must also friendly cost-effective. This manuscript proposes a hierarchy for various waste, from agricultural activities, urban solids food processing industries, even wood industries. proposed number recommendations aimed at increasing biomass, in order reach objective carbon neutrality comply principles circular economy.
Язык: Английский
Процитировано
2
Polymers, Год журнала: 2023, Номер 15(23), С. 4563 - 4563
Опубликована: Ноя. 28, 2023
Polymeric drug delivery technology, which allows for medicinal ingredients to enter a cell more easily, has advanced considerably in recent decades. Innovative medication strategies use biodegradable and bio-reducible polymers, progress the field been accelerated by future possible research applications. Natural polymers utilized polymeric systems include arginine, chitosan, dextrin, polysaccharides, poly(glycolic acid), poly(lactic hyaluronic acid. Additionally, poly(2-hydroxyethyl methacrylate), poly(N-isopropyl acrylamide), poly(ethylenimine), dendritic bioabsorbable as well biomimetic bio-related drug-free macromolecular therapies have employed delivery. Different synthetic natural biomaterials are clinical phase mitigate different diseases. Drug methods using becoming increasingly common pharmaceutical industry, with biocompatible copolymers dendrimers having helped cure cancer systems. This review discusses all above components how, combining biological approaches, micro- nano-drug can result revolutionary gene devices.
Язык: Английский
Процитировано
27
Advances in Colloid and Interface Science, Год журнала: 2024, Номер 328, С. 103158 - 103158
Опубликована: Апрель 16, 2024
Язык: Английский
Процитировано
12
Polymer Testing, Год журнала: 2024, Номер 130, С. 108321 - 108321
Опубликована: Янв. 1, 2024
This study addresses the critical issue of removing copper(II) ions from water using an eco-friendly approach with natural biomaterials. Alginate, a polysaccharide, is employed as primary adsorption material. The involves conversion alginate into nanoparticles, and ternary blend prepared by mixing nanoparticles carboxymethyl cellulose polyethylene glycol (AL-NPs/CMC/PEG). blend's morphological structural transformations have been comprehensively investigated techniques such DLS, FT-IR, XRD, TGA, SEM. Batch experiments were conducted systematically to investigate crucial parameters, contact time (60–300 min), initial copper concentration (62.5 ppm–1000 ppm), solution pH (2–8), adsorbent dosage (1–5 g). results obtained are highly encouraging, revealing impressive 80.9 % efficiency in removal ions. acquired experimental data then subjected analysis Langmuir Freundlich, isotherm, well pseudo-first pseudo-second-order kinetics studies. outcomes these isotherm models indicated favorable fit Freundlich suggesting strong affinity between metal Furthermore, kinetic studies revealed that process closely adheres kinetics, underlining reliability process. From desorption studies, 0.1 M HCl was extremely effective eluant when compared HNO3 EDTA. It could be reused three appreciate efficiency. research underscores potential for environmentally sustainable address persistent environmental challenge posed ion contamination.
Язык: Английский
Процитировано
11
Carbohydrate Polymer Technologies and Applications, Год журнала: 2024, Номер 7, С. 100428 - 100428
Опубликована: Янв. 8, 2024
Bioactive films based on sodium carboxymethyl tragacanth gum (CMT) and polyvinyl alcohol (PVA) enriched with clove extract (CE) for potential wound healing applications were fabricated by the solution casting method. The characterized FTIR, XRD, EDX, SEM, TGA analyses. XRD pattern of CMT/PVA/CE5% showed an amorphous structure broad peaks, suggesting that presence CE led to a reduction in crystallinity increase amorphousness polymer film. high water absorption capacity swelled up 80% over 24 hours formulation crosslinked 15% citric acid. Excellent biodegradability 88% was observed soil 40 days CMT/PVA/CE5%. CMT/PVA improved antioxidant activity 92% within 30 minutes. Strong antibacterial effects film against Salmonella enterica Staphylococcus aureus, inhibition zone diameters 20 mm 18 mm, respectively. Across concentrations from 25-600 μg/mL, displayed cell viability cultured human dermal fibroblasts after 48 hours. results indicated bioactive can be employed as effective, non-toxic dressings infection prevention promotion capabilities.
Язык: Английский
Процитировано
11
International Journal of Pharmaceutics, Год журнала: 2024, Номер 656, С. 124099 - 124099
Опубликована: Апрель 16, 2024
Язык: Английский
Процитировано
10
Coordination Chemistry Reviews, Год журнала: 2024, Номер 518, С. 216093 - 216093
Опубликована: Июль 25, 2024
Язык: Английский
Процитировано
10
International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(10), С. 5359 - 5359
Опубликована: Май 14, 2024
Oromucosal drug delivery, both local and transmucosal (buccal), is an effective alternative to traditional oral parenteral dosage forms because it increases bioavailability reduces systemic toxicity. The mucosa has a good blood supply, which ensures that molecules enter the circulation directly, avoiding metabolism during first passage through liver. At same time, number of barriers, including mucus, epithelium, enzymes, immunocompetent cells, are designed prevent entry foreign substances into body, also complicates absorption drugs. development oromucosal delivery systems based on mucoadhesive biopolymers their derivatives (especially thiolated catecholated derivatives) promising strategy for pharmaceutical safe forms. Solid, semi-solid liquid formulations have several advantageous properties, such as prolonged residence time due high mucoadhesion, unidirectional modified release capabilities, enhanced permeability. Biopolymers non-toxic, biocompatible, biodegradable may possess intrinsic bioactivity. A rational approach design requires understanding anatomy/physiology physicochemical biopharmaceutical properties molecule/biopolymer, presented in this review. This review summarizes advances (e.g., patches, buccal tablets, hydrogel systems), nanotechnology-based biopolymer nanoparticle solid lipid particles, liposomes, polyelectrolyte hybrid nanoparticles, etc.).
Язык: Английский
Процитировано
8