Foods,
Год журнала:
2024,
Номер
13(23), С. 3958 - 3958
Опубликована: Дек. 8, 2024
The
purpose
of
this
study
was
to
design
nanocarriers
with
small-size
and
antioxidant
properties
for
the
effective
encapsulation
curcumin.
Here,
procyanidins,
vanillin,
amino
acids
were
used
successfully
prepare
a
controllable
size
in
range
328~953
nm
endow
ability
based
on
one-step
self-assembly
method.
reaction
involved
Mannich
phenolic
hydroxyl
groups
aldehyde
acids.
Subsequently,
curcumin
nanoparticles
prepared
by
loading
nanocarrier,
efficiency
85.97%.
Compared
free
curcumin,
capacity
photothermal
stability
embedded
significantly
improved,
it
could
be
slowly
released
into
simulated
digestive
fluid.
Moreover,
using
corticosterone-induced
PC12
cell
injury
model,
viability
increased
23.77%
after
intervention
nanoparticles,
cellular
also
improved.
work
can
effectively
improve
solubility,
stability,
bioactivity
which
provides
reference
embedding
delivery
other
hydrophobic
bioactive
compounds.
Abstract
Acmella
oleracea
L.
(Asteraceae),
commonly
known
as
the
toothache
plant,
is
a
tropical
herb
with
significant
therapeutic
potential.
Traditionally,
it
has
been
used
for
its
analgesic
and
sialagogue
properties,
distinctive
yellow
flower
crest.
This
review
addresses
current
gaps
in
understanding
of
pharmacological
properties
aims
to
provide
comprehensive
analysis
A
thorough
literature
was
conducted
using
databases
such
Google
Scholar,
ScienceDirect,
PubMed/MedLine.
The
findings
indicate
that
.
contains
variety
phytochemicals,
including
spilanthol,
which
exhibit
diverse
activities
antioxidant,
anti-inflammatory,
immunomodulatory,
antinociceptive,
pronociceptive,
antibacterial,
antifungal,
antidiabetic,
diuretic,
vasorelaxant
effects.
results
highlight
medicinal
potential
A.
while
also
identifying
areas
further
research,
particularly
regarding
toxicological
impacts
on
humans
animals.
guide
future
studies
health
benefits
safety
this
plant.
Foods,
Год журнала:
2024,
Номер
13(23), С. 3958 - 3958
Опубликована: Дек. 8, 2024
The
purpose
of
this
study
was
to
design
nanocarriers
with
small-size
and
antioxidant
properties
for
the
effective
encapsulation
curcumin.
Here,
procyanidins,
vanillin,
amino
acids
were
used
successfully
prepare
a
controllable
size
in
range
328~953
nm
endow
ability
based
on
one-step
self-assembly
method.
reaction
involved
Mannich
phenolic
hydroxyl
groups
aldehyde
acids.
Subsequently,
curcumin
nanoparticles
prepared
by
loading
nanocarrier,
efficiency
85.97%.
Compared
free
curcumin,
capacity
photothermal
stability
embedded
significantly
improved,
it
could
be
slowly
released
into
simulated
digestive
fluid.
Moreover,
using
corticosterone-induced
PC12
cell
injury
model,
viability
increased
23.77%
after
intervention
nanoparticles,
cellular
also
improved.
work
can
effectively
improve
solubility,
stability,
bioactivity
which
provides
reference
embedding
delivery
other
hydrophobic
bioactive
compounds.
