Preparation and Characterization of Small-Size and Strong Antioxidant Nanocarriers to Enhance the Stability and Bioactivity of Curcumin DOI Creative Commons
Shanshan Tie,

Yu-Jin Yang,

Jiawei Ding

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(23), P. 3958 - 3958

Published: Dec. 8, 2024

The purpose of this study was to design nanocarriers with small-size and antioxidant properties for the effective encapsulation curcumin. Here, procyanidins, vanillin, amino acids were used successfully prepare a controllable size in range 328~953 nm endow ability based on one-step self-assembly method. reaction involved Mannich phenolic hydroxyl groups aldehyde acids. Subsequently, curcumin nanoparticles prepared by loading nanocarrier, efficiency 85.97%. Compared free curcumin, capacity photothermal stability embedded significantly improved, it could be slowly released into simulated digestive fluid. Moreover, using corticosterone-induced PC12 cell injury model, viability increased 23.77% after intervention nanoparticles, cellular also improved. work can effectively improve solubility, stability, bioactivity which provides reference embedding delivery other hydrophobic bioactive compounds.

Language: Английский

The NF-κB Pathway: Key Players in neurocognitive functions and related disorders DOI Creative Commons

Danfeng Yang,

Junwei Su,

Yeru Chen

et al.

European Journal of Pharmacology, Journal Year: 2024, Volume and Issue: 984, P. 177038 - 177038

Published: Oct. 5, 2024

Language: Английский

Citations

2

Pharmacological and phytochemical review of Acmella oleracea: a comprehensive analysis of its therapeutic potential DOI Creative Commons
Asma Aktar, Md. Shimul Bhuia,

Shamim Molla

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 6(8)

Published: July 30, 2024

Abstract Acmella oleracea L. (Asteraceae), commonly known as the toothache plant, is a tropical herb with significant therapeutic potential. Traditionally, it has been used for its analgesic and sialagogue properties, distinctive yellow flower crest. This review addresses current gaps in understanding of pharmacological properties aims to provide comprehensive analysis A thorough literature was conducted using databases such Google Scholar, ScienceDirect, PubMed/MedLine. The findings indicate that . contains variety phytochemicals, including spilanthol, which exhibit diverse activities antioxidant, anti-inflammatory, immunomodulatory, antinociceptive, pronociceptive, antibacterial, antifungal, antidiabetic, diuretic, vasorelaxant effects. results highlight medicinal potential A. while also identifying areas further research, particularly regarding toxicological impacts on humans animals. guide future studies health benefits safety this plant.

Language: Английский

Citations

1

Antioxidant strategies and oxidative stress dynamics in chronic kidney disease: an integrative insight DOI
Ruhul Amin,

Biplab Kumer Dey,

Faruk Alam

et al.

Minerva Biotechnology and Biomolecular Research, Journal Year: 2024, Volume and Issue: 36(3)

Published: Oct. 1, 2024

Language: Английский

Citations

1

Exploring the molecular mechanisms of curcumin in modulating memory impairment in neurodegenerative disorders DOI
Yousef Baghcheghi,

Fateme Razazpour,

Faezeh Mirzaee

et al.

Molecular Biology Reports, Journal Year: 2024, Volume and Issue: 52(1)

Published: Dec. 9, 2024

Language: Английский

Citations

1

Preparation and Characterization of Small-Size and Strong Antioxidant Nanocarriers to Enhance the Stability and Bioactivity of Curcumin DOI Creative Commons
Shanshan Tie,

Yu-Jin Yang,

Jiawei Ding

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(23), P. 3958 - 3958

Published: Dec. 8, 2024

The purpose of this study was to design nanocarriers with small-size and antioxidant properties for the effective encapsulation curcumin. Here, procyanidins, vanillin, amino acids were used successfully prepare a controllable size in range 328~953 nm endow ability based on one-step self-assembly method. reaction involved Mannich phenolic hydroxyl groups aldehyde acids. Subsequently, curcumin nanoparticles prepared by loading nanocarrier, efficiency 85.97%. Compared free curcumin, capacity photothermal stability embedded significantly improved, it could be slowly released into simulated digestive fluid. Moreover, using corticosterone-induced PC12 cell injury model, viability increased 23.77% after intervention nanoparticles, cellular also improved. work can effectively improve solubility, stability, bioactivity which provides reference embedding delivery other hydrophobic bioactive compounds.

Language: Английский

Citations

1