BIO Web of Conferences,
Год журнала:
2024,
Номер
139, С. 06008 - 06008
Опубликована: Янв. 1, 2024
About
60
samples
were
collected
from
patients
with
varicella
zoster,
including
24
males
and
36
females,
as
well
healthy
people,
which
included
29
(15
14
females),
aged
between
15
years.
Data
in
the
holy
city
of
Najaf
November,
2022
July,
2023.
VZV
selected
Sadr
Medical
City
private
laboratories.
The
research
used
BD
FACS
Canto
II
Flow
Cytometry
technology
to
measure
CD4
CD8
cells/ml
blood
controls.
majority
fell
within
age
groups
26–34
36–45,
constituting
approximately
25%,
a
mean
standard
deviation
37.17
±
12.38.
Conversely,
control
group
mostly
belonged
25
years
above,
representing
about
34.48%,
26.86
4.74.
results
revealed
that
exhibited
significantly
decrease
count
(303.7833
64.276)
compared
(626.103
122.07)
(p-value
<
0.0001).
Patients
Varicella-Zoster
Virus
(VZV)
showed
significant
increase
(1197.717
201.369)
(580.379
98.391)
p-value
≤
0.0001.
Current Pharmaceutical Design,
Год журнала:
2024,
Номер
30(31), С. 2445 - 2467
Опубликована: Май 10, 2024
In
recent
years,
the
field
of
nanotechnology
has
brought
about
significant
advancements
that
have
transformed
landscape
disease
diagnosis,
prevention,
and
treatment,
particularly
in
realm
medical
science.
Among
various
approaches
to
nanoparticle
synthesis,
green
synthesis
method
garnered
increasing
attention.
Silver
nanoparticles
(AgNPs)
emerged
as
noteworthy
nanomaterials
within
spectrum
metallic
employed
for
biomedical
applications.
AgNPs
possess
several
key
attributes
make
them
highly
valuable
field.
They
are
biocompatible,
cost-effective,
environmentally
friendly,
rendering
suitable
bioengineering
Notably,
found
a
prominent
role
domain
cancer
diagnosis.
Research
investigations
provided
evidence
AgNPs'
anticancer
activity,
which
involves
mechanisms
such
DNA
damage,
cell
cycle
arrest,
induction
apoptosis,
regulation
specific
cytokine
genes.
The
primarily
reduction
silver
ions
by
reducing
agents.
Interestingly,
natural
products
living
organisms
proven
be
effective
sources
generation
precursor
materials
used
AgNP
synthesis.
This
comprehensive
review
aims
summarize
aspects
AgNPs,
including
their
characterization,
properties,
biogenic
Furthermore,
highlights
potential
applications
these
combating
cancer.
Medicine,
Год журнала:
2024,
Номер
103(20), С. e38117 - e38117
Опубликована: Май 17, 2024
Human
immunodeficiency
virus
(HIV)
infection
continues
to
pose
significant
global
health
challenges,
necessitating
advancements
in
diagnostic
and
prognostic
approaches
optimize
disease
management.
While
primarily
recognized
for
their
roles
allergic
responses,
mast
cells
have
emerged
as
potential
markers
with
significance
the
context
of
HIV/AIDS.
This
paper
aims
synthesize
current
insights
delineate
future
directions
regarding
utility
cell
diagnosing
HIV
infection,
predicting
progression,
guiding
therapeutic
strategies.
Mast
cells,
equipped
distinct
such
tryptase,
chymase,
carboxypeptidase
A3,
c-kit/CD117
receptors,
exhibit
tissue-specific
expression
patterns
that
offer
indicators
infection.
Understanding
dynamics
these
different
tissues
body
fluids
holds
promise
accurate
diagnosis,
staging,
monitoring
treatment
responses.
Moreover,
HIV/AIDS
lies
predict
immune
dysregulation,
clinical
outcomes.
The
integration
into
applications
offers
promising
avenues
refining
assays,
patient
protocols,
strategies
Future
research
involve
development
novel
tools
targeted
therapies
based
on
cell-specific
markers,
potentially
revolutionizing
practice
enhancing
care
management
Continued
investigations
markers’
implications
hold
immense
advance
our
understanding
improve
outcomes
Herpes
simplex
virus
type
1
(HSV-1)
is
a
globally
widespread
that
causes
and
associates
with
wide
range
of
diseases,
including
herpes
encephalitis,
keratitis,
labialis.
The
interaction
between
HSV-1
the
host
involves
complex
immune
response
mechanisms,
recognition
viral
invasion,
maintenance
latent
infection,
triggering
reactivation.
Antiviral
therapy
core
treatment
for
infections.
Meanwhile,
vaccine
development
employs
different
strategies
methods,
several
promising
types
have
emerged,
such
as
live
attenuated,
protein
subunit,
nucleic
acid
vaccines,
offering
new
possibilities
prevention
infection.
Moreover,
can
be
modified
into
therapeutic
vector
gene
tumour
immunotherapy.
This
review
provides
an
in-depth
summary
infection-associated
innate
adaptive
responses,
disease
pathogenesis,
current
approaches,
recent
advances
in
development,
applications
cancer
treatment.
Through
systematic
multiple
aspects
HSV-1,
this
study
aims
to
provide
comprehensive
detailed
reference
public
on
prevention,
control,
HSV-1.
