Hydrogen bond-promoted regio- and stereoselective synthesis of isoindoline derivatives through Pd-catalyzed isocyanide insertion reaction involving aziridines

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(6), С. 1775 - 1781

Опубликована: Янв. 1, 2024

We have successfully demonstrated an efficient and practical Pd-catalyzed reaction between aziridine isocyanide, leading to the synthesis of isoindoline derivatives in moderate good yields.

Язык: Английский

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Synthesis of 4-(Phenylchalcogenyl)tetrazolo[1,5-a]quinolines by Bicyclization of 2-Azidobenzaldehydes with Phenylchalcogenylacetonitrile

Molecules, Год журнала: 2023, Номер 28(13), С. 5036 - 5036

Опубликована: Июнь 27, 2023

A general methodology to access valuable 4-(phenylchalcogenyl)tetrazolo[1,5-a]quinolines was developed by the reaction of 2-azidobenzaldehyde with phenylchalcogenylacetonitriles (sulfur and selenium) in presence potassium carbonate (20 mol%) as a catalyst. The reactions were conducted using mixture dimethylsulfoxide water (7:3) solvent at 80 °C for 4 h. This new presents good functional group tolerance electron-deficient electron-rich substituents, affording total twelve different selectively moderate excellent yields. structure synthesized 4-(phenylselanyl)tetrazolo[1,5-a]quinoline confirmed X-ray analysis.

Язык: Английский

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Solvent-involved synthesis of pyrrolidin-5-one-2-carboxamides via a sequential Ugi/olefination reaction

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(10), С. 2780 - 2785

Опубликована: Янв. 1, 2024

An unprecedented multi-component reaction with solvent participation and a novel conversion of sulfur ylides was developed via Ugi/olefination to construct pyrrolidin-5-one-2-carboxamides.

Язык: Английский

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Design and synthesis of tetrazole-linked quinazoline derivatives and their bioactivities against Microcystis aeruginosa FACHB905

Tetrahedron Letters, Год журнала: 2024, Номер 140, С. 155046 - 155046

Опубликована: Апрель 1, 2024

Язык: Английский

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