Synthesis of 4-(Phenylchalcogenyl)tetrazolo[1,5-a]quinolines by Bicyclization of 2-Azidobenzaldehydes with Phenylchalcogenylacetonitrile DOI Creative Commons

Loana I. Monzon,

Nicole Cristina Rocha,

Gabriela T. Quadros

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(13), P. 5036 - 5036

Published: June 27, 2023

A general methodology to access valuable 4-(phenylchalcogenyl)tetrazolo[1,5-a]quinolines was developed by the reaction of 2-azidobenzaldehyde with phenylchalcogenylacetonitriles (sulfur and selenium) in presence potassium carbonate (20 mol%) as a catalyst. The reactions were conducted using mixture dimethylsulfoxide water (7:3) solvent at 80 °C for 4 h. This new presents good functional group tolerance electron-deficient electron-rich substituents, affording total twelve different selectively moderate excellent yields. structure synthesized 4-(phenylselanyl)tetrazolo[1,5-a]quinoline confirmed X-ray analysis.

Language: Английский

Hydrogen bond-promoted regio- and stereoselective synthesis of isoindoline derivatives through Pd-catalyzed isocyanide insertion reaction involving aziridines DOI

Shuang Zheng,

Haojie Fan,

Shanshan Liu

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(6), P. 1775 - 1781

Published: Jan. 1, 2024

We have successfully demonstrated an efficient and practical Pd-catalyzed reaction between aziridine isocyanide, leading to the synthesis of isoindoline derivatives in moderate good yields.

Language: Английский

Citations

2
Solvent-involved synthesis of pyrrolidin-5-one-2-carboxamides via a sequential Ugi/olefination reaction DOI
Na Chen,

Tianyu Long,

Han‐Han Kong

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(10), P. 2780 - 2785

Published: Jan. 1, 2024

An unprecedented multi-component reaction with solvent participation and a novel conversion of sulfur ylides was developed via Ugi/olefination to construct pyrrolidin-5-one-2-carboxamides.

Language: Английский

Citations

0
Design and synthesis of tetrazole-linked quinazoline derivatives and their bioactivities against Microcystis aeruginosa FACHB905 DOI
Xu Yang, Ding Yuan, Yong Zhang

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: 140, P. 155046 - 155046

Published: April 1, 2024

Language: Английский

Citations

0
Synthesis of 4-(Phenylchalcogenyl)tetrazolo[1,5-a]quinolines by Bicyclization of 2-Azidobenzaldehydes with Phenylchalcogenylacetonitrile DOI Creative Commons

Loana I. Monzon,

Nicole Cristina Rocha,

Gabriela T. Quadros

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(13), P. 5036 - 5036

Published: June 27, 2023

A general methodology to access valuable 4-(phenylchalcogenyl)tetrazolo[1,5-a]quinolines was developed by the reaction of 2-azidobenzaldehyde with phenylchalcogenylacetonitriles (sulfur and selenium) in presence potassium carbonate (20 mol%) as a catalyst. The reactions were conducted using mixture dimethylsulfoxide water (7:3) solvent at 80 °C for 4 h. This new presents good functional group tolerance electron-deficient electron-rich substituents, affording total twelve different selectively moderate excellent yields. structure synthesized 4-(phenylselanyl)tetrazolo[1,5-a]quinoline confirmed X-ray analysis.

Language: Английский

Citations

1