Materials Science and Engineering R Reports, Год журнала: 2025, Номер 164, С. 100971 - 100971
Опубликована: Март 12, 2025
Язык: Английский
Advanced Functional Materials, Год журнала: 2023, Номер 33(31)
Опубликована: Май 10, 2023
Abstract Biomarkers are primary indicators for precise diagnosis and treatment. The early identification of health biomarkers has been sustained by the evolutionary success in sensor technologies. Among them, graphene field‐effect transistor (GFET) biosensors have exhibited major advantages such as an ultrashort response time, high sensitivity, easy operation, capability integration, label‐free detection. Owing to atomic thickness, restricts charge carrier flow merely at material surface responds foreign stimuli directly, leading effective signal acquisition transmission. Here, this review summarizes latest advances GFET a comprehensive manner that contains device design, working principle, functionalization, proof‐of‐concept applications. It provides survey with regard biomarker analysis single‐device level integrated prototypes include wearable sensors, biomimetic systems, healthcare electronics, diagnostic platforms. Moreover, there is discussion on long‐standing research efforts outlook future development systems from lab fab.
Язык: Английский
Процитировано
27
Journal of Colloid and Interface Science, Год журнала: 2023, Номер 645, С. 76 - 85
Опубликована: Апрель 29, 2023
Язык: Английский
Процитировано
24
BMEMat, Год журнала: 2024, Номер unknown
Опубликована: Авг. 2, 2024
Abstract In recent years, tissue engineering has emerged as a cutting‐edge approach for the treatment of spinal cord injury (SCI) owing to its remarkable capabilities. It can create living tissues with robust vitality, achieve maximal repair minimal cell usage, and facilitate seamless reconstruction unmatched plasticity, all while addressing immune rejection issues. Among these advancements, one‐dimensional (1D) materials have garnered significant attention. Their morphology closely resembles extracellular matrix environment, thereby fostering elongation dendrites axons on neurons greatly enhancing prospects SCI repair. With keen focus latest advancements in application 1D nanomaterials nerve repair, this review delves into several key aspects. Firstly, it explores “bottom‐up” synthesizing nanomaterials. Secondly, examines mechanisms by which influence neural engineering. Thirdly, presents various strategies aimed at optimizing performance materials, efficiency Lastly, discusses current challenges future facing fascinating field. We aspire that comprehensive will provide profound understanding development inspire wider audience potential.
Язык: Английский
Процитировано
10
Nanoscale, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Current molecular tests for tuberculosis (TB), such as whole genome sequencing and Xpert Mycobacterium tuberculosis/rifampicin resistance assay, exhibit limited sensitivity necessitate the pre-amplification step of target DNA. This limitation greatly increases detection time poses an increased risk infection. Here, we present a graphene field-effect transistor (GFET) based on CRISPR/Cas system detecting tuberculosis. The CRISPR/Cas12a has ability to specifically recognize cleave By integrating onto FET platform utilizing its electrical amplification capability, achieve rapid sensitive without requiring sample pre-amplification, with limit (LoD) low 2.42 × 10-18 M. Cas12a-GFET devices can differentiate 30 positive cases from 56 serum samples within 5 minutes. These findings highlight immense potential in future biological analysis clinical diagnosis.
Язык: Английский
Процитировано
2
Materials Science and Engineering R Reports, Год журнала: 2025, Номер 164, С. 100971 - 100971
Опубликована: Март 12, 2025
Язык: Английский
Процитировано
1