Nanozyme-based biosensor for organophosphorus pesticide monitoring: Functional design, biosensing strategy, and detection application

TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 165, С. 117152 - 117152

Опубликована: Июнь 20, 2023

Язык: Английский

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Iridium Complex with Specific Intercalation in the G-Quadruplex: A Phosphorescence and Electrochemiluminescence Dual-Mode Homogeneous Biosensor for Enzyme-Free and Label-Free Detection of MicroRNA

ACS Sensors, Год журнала: 2023, Номер 8(4), С. 1529 - 1535

Опубликована: Март 24, 2023

Design and exploitation of high-property multifunctional emitters for achieving immobilization-free, label-free, enzyme-free, dual-mode determination microRNA (miRNA) with high sensitivity selectivity are particularly urgent but remain a huge challenge. Herein, the first time, we reported an Ir3+-based N-heterocyclic complex, namely, IrPyPt, ascertained its phosphorescence electrochemiluminescence (ECL) dual-emission behavior in homogeneous solution, discovered turn-up signal-off ECL response to G-quadruplex DNA over other DNAs. Inspired by this, IrPyPt was pioneered as emitter combine nucleic acid probes (ON1 ON2) developing biosensor, which applied highly sensitive, credible analysis miRNA-21 used target analyte. triggered hybridization chain reaction ON1 ON2 generate abundant G-quadruplexes, caught yield IrPyPt@G-quadruplex, intramolecular rotary motion inhibited unable diffuse electrode, contributing boosted emission sharply declined emission. With this design, achieved limits detection down 1.40 0.18 pM, respectively. Furthermore, biosensor triumphantly determine concentration cancer cell lysates thus provided great potential alternative miRNA-related diseases' early accurate diagnosis.

Язык: Английский

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UiO-66/Carboxylated Multiwalled Carbon Nanotube Composites for Highly Efficient and Stable Voltammetric Sensors for Gatifloxacin

ACS Applied Nano Materials, Год журнала: 2023, Номер 6(20), С. 19403 - 19413

Опубликована: Окт. 12, 2023

The excessive use of gatifloxacin (GAT) can seriously pollute the environment and damage human health. Therefore, reliable detection its concentration is essential for environmental protection physical Herein, an efficient stable voltammetric sensor based on zirconium-based metal–organic framework/carboxylated multiwalled nanotube nanocomposites (UiO-66/MWCNT-COOH) was constructed determination GAT. morphologies, microstructures, electrochemical properties UiO-66/MWCNT-COOH were investigated by using various microscopic, spectroscopic, techniques. showed good electrocatalytic activity GAT oxidation with remarkable response signals, which primarily attributed to synergistic effect from UiO-66 MWCNT-COOH. Electrochemical kinetics studies revealed that irreversible diffusion-limited reaction involving two protons electrons. anodic peak current linearly correlated in range 0.05 10 μM a low limit 0.0075 μM. Moreover, demonstrated high selectivity, reproducibility, repeatability as well extraordinary long-term stability (at least 7 weeks). proposed reliably detected trace effluent, milk, serum, eye drops satisfactory recoveries. Together outstanding merits such cost, robust response, short assay time, sensitivity, shows enormous prospects situ multiple antibiotics.

Язык: Английский

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Lamellar α-Zirconium Phosphate Nanoparticles Supported on N-Doped Graphene Nanosheets as Electrocatalysts for the Detection of Levofloxacin

ACS Applied Nano Materials, Год журнала: 2023, Номер 6(18), С. 17040 - 17052

Опубликована: Сен. 6, 2023

The excessive use of levofloxacin (LEV) can lead to significant environmental pollution, while also damaging human health. accurate detection its concentration is therefore essential protect both the environment and Herein, we report simple synthesis α-zirconium phosphate supported on nitrogen-doped graphene nanosheets (α-ZrP/NG) application in voltammetric determination trace LEV real samples. surface morphology, microstructure, electrochemical properties α-ZrP/NG were investigated by microscopic spectroscopic techniques. analytical parameters, including accumulation potential, time, loading volume, buffer pH, optimized improve electrocatalytic sensing performance α-ZrP/NG. Owing synergetic interaction between α-ZrP NG, proposed sensor exhibited an excellent activity for electrical oxidation LEV. In range 0.01–5.0 μM, anodic peak current increased linearly with increase concentration, limit was 2.6 nmol L–1. Finally, levels wastewater, serum, milk, eye drop samples determined using system combined a glassy carbon electrode give satisfactory recoveries (98.48–103.2%), indicating that prepared demonstrates promise environmental, food, drug monitoring applications.

Язык: Английский

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Nanozymes: powerful catalytic materials for environmental pollutant detection and degradation

Environmental Science Nano, Год журнала: 2024, Номер 11(3), С. 766 - 796

Опубликована: Янв. 1, 2024

Here we made a critical review on nanozyme-involved detection and degradation of environmental pollutants, the research progress achieved in last five years was emphatically concluded.

Язык: Английский

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Temperature-resilient and sustainable Mn-MOF oxidase-like nanozyme (UoZ-4) for total antioxidant capacity sensing in some citrus fruits: Breaking the temperature barrier

Food Chemistry, Год журнала: 2024, Номер 448, С. 139170 - 139170

Опубликована: Март 29, 2024

Язык: Английский

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Manganese cobalt-MOF@carbon nanofiber-based non-enzymatic histamine sensor for the determination of food freshness

Analytical and Bioanalytical Chemistry, Год журнала: 2023, Номер 415(17), С. 3487 - 3501

Опубликована: Май 23, 2023

Язык: Английский

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Platinum-nickel nanoparticle-based oxidase-like nanozyme for colorimetric/photothermal dual-mode detection of organophosphorus pesticides

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 412, С. 135861 - 135861

Опубликована: Апрель 22, 2024

Язык: Английский

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Recent advances in metal oxide nanozyme-based optical biosensors for food safety assays

Food Chemistry, Год журнала: 2024, Номер 447, С. 139019 - 139019

Опубликована: Март 13, 2024

Язык: Английский

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Bioenzyme-free dual-mode sensing for organophosphorus pesticides based on UiO-66-NH2 MOFs encapsulated tris(2,2′-bipyridyl) ruthenium(II)

Sensors and Actuators B Chemical, Год журнала: 2024, Номер 413, С. 135847 - 135847

Опубликована: Апрель 24, 2024

Язык: Английский

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