Nanoscale, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Biohybrid microrobot (Spirulina, Fe 3 O 4 , ZIF-8) rapidly adsorbs organic pollutants and navigates narrow gaps directionally via magnetic steering.
Язык: Английский
Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12
Опубликована: Фев. 21, 2024
Research and development in the field of micro/nano-robots have made significant progress past, especially clinical medicine, where further research may lead to many revolutionary achievements. Through experiment microrobots, a controllable drug delivery system will be realized, which solve problems treatment. In this work, we design study ability magnetic-driven hydrogel microrobots carry Lycorine hydrochloride (LH) inhibit colorectal cancer (CRC) cells. We successfully designed magnetic driven, biocompatible carrying microsphere robot with Fe 3 O 4 particles inside, can achieve response, confirmed that it transport through fluorescence microscope. demonstrated motion mode driven by rotating external field. This driving method allows move precise manner, providing tremendous potential for their use various applications. Finally, selected LH loaded into microrobot series experiments. significantly inhibited CRC cells proliferation dose- time-dependent manner. proliferation, mobility induced apoptosis. improve therapeutic effect drugs on tumors.
Язык: Английский
Процитировано
3
Chemical Engineering Journal, Год журнала: 2024, Номер 494, С. 153085 - 153085
Опубликована: Июнь 13, 2024
Язык: Английский
Процитировано
3
Frontiers in Chemistry, Год журнала: 2025, Номер 13
Опубликована: Фев. 6, 2025
In recent years, medical micro-/nanorobots (MNRs) have emerged as a promising technology for diagnosing and treating malignant tumors. MNRs enable precise, targeted actions at the cellular level, addressing several limitations of conventional cancer diagnosis treatment, such insufficient early diagnosis, nonspecific drug delivery, chemoresistance. This review provides an in-depth discussion propulsion mechanisms MNRs, including chemical fuels, external fields (light, ultrasound, magnetism), biological propulsion, hybrid methods, highlighting their respective advantages limitations. Additionally, we discuss novel approaches tumor precision surgery, emphasizing potential clinical applications. Despite significant advancements, challenges biocompatibility, efficiency, translation persist. examines current state MNR applications outlines future directions development, with aim enhancing diagnostic therapeutic efficacy facilitating integration into practice.
Язык: Английский
Процитировано
0
Langmuir, Год журнала: 2025, Номер unknown
Опубликована: Фев. 11, 2025
Inspired by natural organisms, actuators have shown great promise for small swimming robots. However, previous single-stimulus-driven studies limited their effectiveness in complex aquatic environments. In this study, a PINPAM/MWCNT composite actuator was developed. This can be controlled both light and chemical agents to achieve rapid drift on the water surface. It enables programmable trajectory motion water, capable of performing maneuvers such as linear translation, turning, rotation, particularly under infrared light. dovetail configurations, movement control corresponding achieved through agent actuation. The horn-shaped actuator, modeled after horns, propel transport cargos an illumination. Notably, circular spontaneously traverse U-shaped curve without external stimuli. multistimulus-responsive Marangoni significantly broadens application scope miniature actuators, paving new avenues microrobotics inspiring future advancements biomimetic robotics.
Язык: Английский
Процитировано
0
Nanoscale, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Biohybrid microrobot (Spirulina, Fe 3 O 4 , ZIF-8) rapidly adsorbs organic pollutants and navigates narrow gaps directionally via magnetic steering.
Язык: Английский
Процитировано
0