ABSTRACT
Sample
preparation
maintains
a
key
bottleneck
in
the
whole
analytical
procedure.
Solid‐phase
sorbents
(SPSs)
have
garnered
increasing
attention
sample
research
due
to
their
crucial
roles
achieving
high
clean‐up
and
enrichment
efficiency
analysis
of
trace
targets
present
complex
matrices.
Novel
nanoscale
materials
with
improved
characteristics
considerable
interest
across
different
scientific
disciplines
limited
capabilities
traditional
bulk‐scale
materials.
The
purpose
this
review
is
offer
thorough
summary
latest
developments
uses
SPSs
preparing
samples
for
chromatographic
analysis,
focusing
on
years
2020–2024.
techniques
are
examined,
such
as
metal–organic
frameworks
(MOFs),
covalent
organic
(COFs),
carbon
nanoparticles
(CNPs),
molecularly
imprinted
polymers
(MIPs),
metallic
nanomaterials
(MNs).
Examining
pros
cons
extraction
methods,
including
solid‐phase
(SPE),
magnetic
SPE
(MSPE),
flow‐based
(FBA‐SPE),
microextraction
(SPME),
stir‐bar
sorptive
(SBSE),
dispersive
(DSPE),
main
focus.
Furthermore,
article
presents
utilization
technology
isolating
common
contaminants
various
environmental,
biological,
food
specimens.
We
highlight
persistent
challenges
anticipate
future
advancements
applications
novel
SPSs.
Nano Letters,
Год журнала:
2024,
Номер
24(37), С. 11520 - 11528
Опубликована: Сен. 5, 2024
Small-molecule
biomarkers
are
ubiquitous
in
biological
fluids
with
pathological
implications,
but
major
challenges
persist
their
quantitative
analysis
directly
complex
clinical
samples.
Herein,
a
molecular-sieving
label-free
surface-enhanced
Raman
spectroscopy
(SERS)
biosensor
is
reported
for
selective
of
trace
small-molecule
trimetazidine
(TMZ)
Our
fabricated
by
decorating
superhydrophobic
monolayer
microporous
metal-organic
frameworks
(MOF)
shell-coated
Au
nanostar
nanoparticles
on
silicon
substrate.
The
design
strategy
principally
combines
the
hydrophobic
surface-enabled
physical
confinement
and
preconcentration,
MOF-assisted
molecular
enrichment
sieving
small
molecules,
sensitive
SERS
detection.
utilizes
such
"molecular
confinement-and-sieving"
to
achieve
five
orders-of-magnitude
dynamic
detection
range
limit
≈0.5
nM
TMZ
either
urine
or
whole
blood.
We
further
demonstrate
applicability
our
biosensing
platform
longitudinal
level
samples
mouse
model.
Polymetallic
MOFs
heterostructural
composites
enhance
their
usage
in
a
range
of
sensing
domains
by
combining
two
or
more
different
to
produce
new
MOF-on-MOF
integrated
module.
As
its
widespread
utilization
flavomycin
(Fla),
there
are
currently
complications
with
agricultural
residue
and
the
environment,
consequently,
highly
sensitive,
portable
technology
for
identification
will
be
required
handle
environmental
monitoring
real-time.
In
this
work,
structural
characterization
characteristics
two-layer
heterostructure
investigated
using
epitaxial
growth
method.
Electrons
migrate
from
Fe
metal
center
organic
ligand
primarily
as
result
hydrogen
bonding
between
Fla
surface
Fe-MOF
energy
transfer
amongst
atoms
NH2-MIL-101
(Eu).
The
synergistic
impact
NH2-MIL-101(Eu)
improves
sensitivity
accuracy
detection,
which
has
4.8
nm
detection
limit,
enabling
high
Fla.
Likewise,
we
put
together
handheld
platform
incorporating
aerogel
materials
that
can
meet
expectations
real-time
multiple
actual
sample
fluorescent
offer
an
innovative
viewpoint
on
application
creating
flexible
sensors,
method
visualization
food
safety
early
alerting.
Analytical Methods,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
The
extensive
use
of
antibiotics
poses
significant
public
health
concerns,
including
the
increase
in
drug-resistant
bacteria
and
environmental
pollution,
underscoring
urgent
need
for
rapid,
sensitive,
specific
antibiotic
detection
methods.
Most
current
reviews
on
primarily
focus
categorizing
based
their
types
or
classification
sensors
used,
such
as
electrochemical,
optical,
colorimetric
sensors.
In
contrast,
this
review
proposes
a
novel
systematic
theoretical
framework
using
seven
popular
molecular
recognition
elements-antibodies,
aptamers,
microorganisms,
cells,
peptides,
molecularly
imprinted
polymers
(MIPs),
metal-organic
frameworks
(MOFs)
direct
modalities
briefly
discusses
mechanism
elements
recognition.
Additionally,
it
explores
biosensors
developed
these
elements,
offering
detailed
analysis
strengths
limitations
terms
sensitivity,
specificity,
practicality.
concludes
by
addressing
challenges
future
directions,
providing
comprehensive
perspective
essential
enhancing
food
safety
protecting
health.
Nano Letters,
Год журнала:
2024,
Номер
24(45), С. 14427 - 14436
Опубликована: Окт. 31, 2024
The
preparation
of
high
quantum
yield,
stable,
and
multifunctional
fluorescent
probes
is
great
significance
in
the
fields
biomedicine
photoelectric
sensing.
Here,
a
triphenylamine-based
D−π–A
molecule
(TPA-CN)
was
designed
prepared,
demonstrating
fluorescence
yield
88.84%.
With
polystyrene
nanosphere
as
carrier,
TPA-CN
encapsulated
inside
to
form
intra-nanosphere
confining
domains.
These
nanodomain-enhanced
nanospheres
exhibited
98.21%.
Using
antigen–antibody
specificity
selective
catalytic
activity
bioenzyme,
with
chloramphenicol
model
target,
dual-signal
readout
biosensor
(in
colorimetric
modes)
for
ultrasensitive
instrument-free
determination.
detection
limit
24
pg/mL
within
30
min
mode,
38-fold
more
sensitive
10-fold
faster
than
that
enzyme
linked
immunosorbent
assays.
dynamic
provide
robust
versatile
solution
public
health
environmental
monitoring
needs.
