“All-in-one” self-healing and injectable cationic guar gum hydrogel dressing functionalized by bioactive complexes composed of natural small molecules

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 275, С. 133517 - 133517

Опубликована: Июль 1, 2024

Язык: Английский

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Unveiling the Diverse Principles for Developing Sprayable Hydrogels for Biomedical Applications

Biomacromolecules, Год журнала: 2025, Номер unknown

Опубликована: Янв. 6, 2025

Sprayable hydrogels have emerged as a transformative innovation in biomedical technology, offering versatile, efficient, and minimally invasive platform for various clinical applications. They form gels situ upon tissue contact, enabling seamless application on even complex surfaces. This property is especially useful wound care, drug delivery, engineering, where localized sustained release of therapeutics essential. Formulations can be customized to include bioactive compounds, such growth factors, antibiotics, anti-inflammatory agents, thereby enhancing targeted treatment outcomes. review delves into the fundamental principles governing sprayable hydrogels, emphasizing critical mechanisms cross-linking, shear-thinning properties, thermoresponsive behavior. Furthermore, it highlights recent advancements since 2020, including strategic incorporation agents augment therapeutic efficacy. By examining these core design strategies, this provides comprehensive perspective engineering modern medical

Язык: Английский

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Multifunctional self-healing and pH-responsive hydrogel dressing based on cationic guar gum and hyaluronic acid for on-demand drug release

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140326 - 140326

Опубликована: Янв. 1, 2025

Язык: Английский

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Advances in the study of polysaccharide-based hydrogel wound dressings

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142134 - 142134

Опубликована: Март 1, 2025

Язык: Английский

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Recent advances on chitosan/hyaluronic acid-based stimuli-responsive hydrogels and composites for cancer treatment: A comprehensive review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 135893 - 135893

Опубликована: Сен. 1, 2024

Язык: Английский

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Synergistic adhesion enhancement of double-crosslinking chitosan hydrogel via catechol-Fe3+ coordination and Schiff base

Carbohydrate Polymers, Год журнала: 2025, Номер 356, С. 123380 - 123380

Опубликована: Фев. 12, 2025

Язык: Английский

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A Heterojunction Piezoelectric Antimicrobial Asymmetric Hydrogel for Dynamic Wound Healing and Monitoring

Small, Год журнала: 2025, Номер unknown

Опубликована: Фев. 21, 2025

Abstract Dynamic wound care presents significant challenges for conventional dressings due to the complex environment and high‐frequency motion associated with such injuries. In this study, a multifunctional photo‐crosslinked piezoelectric hydrogel (OAPS) is developed, incorporating heterojunction Se‐doped KH570 modified BaTiO 3 nanoparticles (Se‐BT570 NPs) as core component, designed address antimicrobial monitoring needs in care, particularly at sites movement. The OAPS effectively utilizes inherent dynamic wounds, enhancing efficacy enabling real‐time of human health statuses. This achieved through synergistic effects properties nano‐heterostructures that enable self‐driven charge transfer. Such integration allows dual applications both diagnosis treatment. Experimental results demonstrated exhibits excellent mechanical strength adhesive properties, adapting motion. Additionally, can be activated by environments perform functions, significantly accelerating healing an rate 99.75%. study highlights potential nanomaterials healing, offering promising strategy managing complex, care.

Язык: Английский

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Tri-network PVA/chitosan/gelatin hydrogel modified by tannic acid with self-healing, adhesive and anti-inflammatory properties to accelerate wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142280 - 142280

Опубликована: Март 1, 2025

Язык: Английский

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Polymer Applied in Hydrogel Wound Dressing for Wound Healing: Modification/Functionalization Method and Design Strategies

ACS Biomaterials Science & Engineering, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Hydrogel wound dressings have emerged as a promising solution for healing due to their excellent mechanical and biochemical properties. Over recent years, there has been significant progress in expanding the variety of raw materials used hydrogel formulation along with development advanced modification techniques design approaches that enhance performance. However, comprehensive review encompassing diverse polymer strategies innovations is still lacking literature. This summarizes use natural polymers (e.g., chitosan, gelatin, sodium alginate, hyaluronic acid, dextran) synthetic poly(vinyl alcohol), polyethylene glycol, Pluronic F-127, poly(N-isopropylacrylamide), polyacrylamide, polypeptides) dressings. We further explore advantages limitations these discuss various strategies, including cationic modification, oxidative double-bond catechol etc. The also addresses principles synthesis methods, aligning modifications specific requirements healing. Finally, we future challenges opportunities hydrogel-based

Язык: Английский

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Hydrogel composite scaffold repairs knee cartilage defects: a systematic review

RSC Advances, Год журнала: 2025, Номер 15(13), С. 10337 - 10364

Опубликована: Янв. 1, 2025

Currently, the incidence of cartilage defects in knee joints owing to different causes is increasing every year, and surgery most common treatment strategy.

Язык: Английский

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