“All-in-one” self-healing and injectable cationic guar gum hydrogel dressing functionalized by bioactive complexes composed of natural small molecules

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 275, P. 133517 - 133517

Published: July 1, 2024

Language: Английский

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Unveiling the Diverse Principles for Developing Sprayable Hydrogels for Biomedical Applications

Biomacromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 6, 2025

Sprayable hydrogels have emerged as a transformative innovation in biomedical technology, offering versatile, efficient, and minimally invasive platform for various clinical applications. They form gels situ upon tissue contact, enabling seamless application on even complex surfaces. This property is especially useful wound care, drug delivery, engineering, where localized sustained release of therapeutics essential. Formulations can be customized to include bioactive compounds, such growth factors, antibiotics, anti-inflammatory agents, thereby enhancing targeted treatment outcomes. review delves into the fundamental principles governing sprayable hydrogels, emphasizing critical mechanisms cross-linking, shear-thinning properties, thermoresponsive behavior. Furthermore, it highlights recent advancements since 2020, including strategic incorporation agents augment therapeutic efficacy. By examining these core design strategies, this provides comprehensive perspective engineering modern medical

Language: Английский

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Multifunctional self-healing and pH-responsive hydrogel dressing based on cationic guar gum and hyaluronic acid for on-demand drug release

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140326 - 140326

Published: Jan. 1, 2025

Language: Английский

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Advances in the study of polysaccharide-based hydrogel wound dressings

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142134 - 142134

Published: March 1, 2025

Language: Английский

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Recent advances on chitosan/hyaluronic acid-based stimuli-responsive hydrogels and composites for cancer treatment: A comprehensive review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135893 - 135893

Published: Sept. 1, 2024

Language: Английский

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Chitosan and gelatin based sprayable hydrogels incorporating photothermal and long-acting antibiotic sterilization for infected wound management with shape adaptability

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 350, P. 123046 - 123046

Published: Nov. 20, 2024

Language: Английский

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Synergistic adhesion enhancement of double-crosslinking chitosan hydrogel via catechol-Fe3+ coordination and Schiff base

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 356, P. 123380 - 123380

Published: Feb. 12, 2025

Language: Английский

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A Heterojunction Piezoelectric Antimicrobial Asymmetric Hydrogel for Dynamic Wound Healing and Monitoring

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Abstract Dynamic wound care presents significant challenges for conventional dressings due to the complex environment and high‐frequency motion associated with such injuries. In this study, a multifunctional photo‐crosslinked piezoelectric hydrogel (OAPS) is developed, incorporating heterojunction Se‐doped KH570 modified BaTiO 3 nanoparticles (Se‐BT570 NPs) as core component, designed address antimicrobial monitoring needs in care, particularly at sites movement. The OAPS effectively utilizes inherent dynamic wounds, enhancing efficacy enabling real‐time of human health statuses. This achieved through synergistic effects properties nano‐heterostructures that enable self‐driven charge transfer. Such integration allows dual applications both diagnosis treatment. Experimental results demonstrated exhibits excellent mechanical strength adhesive properties, adapting motion. Additionally, can be activated by environments perform functions, significantly accelerating healing an rate 99.75%. study highlights potential nanomaterials healing, offering promising strategy managing complex, care.

Language: Английский

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Tri-network PVA/chitosan/gelatin hydrogel modified by tannic acid with self-healing, adhesive and anti-inflammatory properties to accelerate wound healing

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142280 - 142280

Published: March 1, 2025

Language: Английский

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Polymer Applied in Hydrogel Wound Dressing for Wound Healing: Modification/Functionalization Method and Design Strategies

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Hydrogel wound dressings have emerged as a promising solution for healing due to their excellent mechanical and biochemical properties. Over recent years, there has been significant progress in expanding the variety of raw materials used hydrogel formulation along with development advanced modification techniques design approaches that enhance performance. However, comprehensive review encompassing diverse polymer strategies innovations is still lacking literature. This summarizes use natural polymers (e.g., chitosan, gelatin, sodium alginate, hyaluronic acid, dextran) synthetic poly(vinyl alcohol), polyethylene glycol, Pluronic F-127, poly(N-isopropylacrylamide), polyacrylamide, polypeptides) dressings. We further explore advantages limitations these discuss various strategies, including cationic modification, oxidative double-bond catechol etc. The also addresses principles synthesis methods, aligning modifications specific requirements healing. Finally, we future challenges opportunities hydrogel-based

Language: Английский

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