Tumor‐Targeted Catalytic Immunotherapy DOI Open Access

En‐Li Yang,

Wuyin Wang, Yingqi Liu

и другие.

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Дек. 15, 2024

Cancer immunotherapy holds significant promise for improving cancer treatment efficacy; however, the low response rate remains a considerable challenge. To overcome this limitation, advanced catalytic materials offer potential in augmenting by modulating immunosuppressive tumor microenvironment (TME) through precise biochemical reactions. Achieving optimal targeting precision and therapeutic efficacy necessitates thorough understanding of properties underlying mechanisms tumor-targeted materials. This review provides comprehensive systematic overview recent advancements their critical role enhancing immunotherapy. It highlights types reactions, construction strategies materials, fundamental targeting, including passive, bioactive, stimuli-responsive, biomimetic approaches. Furthermore, outlines various tumor-specific strategies, encompassing tissue, cell, exogenous TME-responsive, cellular TME strategies. Finally, discussion addresses challenges future perspectives transitioning into clinical applications, offering insights that pave way next-generation therapies provide substantial benefits to patients settings.

Язык: Английский

Advances and future perspectives in thermoelectric cooling technology DOI
Lei Wang,

Tien-Dung Chu,

Shuaishuai Yuan

и другие.

Energy Conversion and Management, Год журнала: 2025, Номер 332, С. 119621 - 119621

Опубликована: Март 13, 2025

Язык: Английский

Процитировано

3

Recent progress of biosensors based on thermoelectric effects for monitoring physical activity and environment monitoring DOI Open Access

Xiao-Jie Tang,

Cai Qi,

Qiang Sun

и другие.

Soft Science, Год журнала: 2025, Номер 5(1)

Опубликована: Фев. 13, 2025

Thermoelectric (TE) materials and sensors have emerged as a frontier in health environmental monitoring, offering silent, simple, reliable alternative to traditional power generation methods by harnessing waste heat into usable electrical energy. They also offer superior stability longevity, making them ideal for long-term monitoring applications. Furthermore, when compared other self-powered biosensors, TE excel their ability operate wide range of temperatures conditions, providing more consistent source sensor operation. This review delves the recent advancements TE-based sensors, highlighting multifunctional capabilities real-time sensing. We explore fundamental principles conversion, including Seebeck effect, assess performance metric, specifically figure-of-merit (ZT ). The integration with flexible wearable electronics is discussed, emphasizing high efficiency mechanical robustness. Applications devices internet things (IoT)-integrated systems are underscored, particularly fire detection personal monitoring. Challenges material limitations, miniaturization, scalability addressed, focus on future research directions enhance sustainability longevity sensors. provides comprehensive overview development technology its trajectory, importance ongoing address current challenges realize these innovative devices.

Язык: Английский

Процитировано

2

Wireless Thermoelectric Hydrogel Recreates Biomimetic Electric Field and Angiogenic Signal Accelerating Diabetic Ulcer Repair DOI

Minhong Tan,

Yuda Liu, Yiyi Wang

и другие.

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Фев. 25, 2025

Abstract Endogenous electric field (EF)‐actuated reepithelization, dermal formation, and growth factors‐induced angiogenesis are crucial for wound healing. It is however, challenging to initiate both endogenous EF factors in diabetic ulcer due severe electrolyte loss hyperglycemia‐resulted endothelial dysfunction. Current therapeutic systems supply electrostimulation by integrating self‐powered conductive materials continue encounter obstacles nondegradability‐induced low biocompatibility anisotropic EF‐resulted limited regeneration. Recombinant also high cost, stability, potential bio‐risk. Herein, a wireless biocompatible thermoelectric hydrogel (HFN) co‐crosslinked biodegradable hyaluronic acid polyether F127 developed achieve effective directional‐EF stimulation. Target‐modified ginseng‐derived exosomes (RGE) further embedded the design of HFN‐RGE enhanced Specifically, recreates biomimetic through “cationic trap” effect trigger robust epithelial fibroblast electrotaxis, meanwhile controlling release precise pro‐angiogenic with unique ability reverse In vivo, demonstrated stimulate reepithelialization, regeneration, nascent vessel network reconstruction. Single‐cell RNA‐seq revealed that activates PPAR signaling‐meditated tissue As such this work provides promising electrical‐biological hybrid system biosafety therapy.

Язык: Английский

Процитировано

1

Thermoelectric Performance of Layered PbBi4Te7 Compound DOI

Hong Zeng,

Liqing Xu, Wei Liu

и другие.

Acta Metallurgica Sinica (English Letters), Год журнала: 2025, Номер unknown

Опубликована: Янв. 22, 2025

Язык: Английский

Процитировано

0

Liquid Metal Enabled Thermoelectric Effects: Fundamental and Application DOI Open Access
Tangzhen Guan, Jianye Gao, Weiqiu Chen

и другие.

Advanced Functional Materials, Год журнала: 2025, Номер unknown

Опубликована: Март 20, 2025

Abstract The thermoelectric (TE) effect, capable of directly converting heat into electrical energy, has catalyzed the development numerous next‐generation functional devices. However, traditional TE generators (TEGs), predominantly composed rigid materials, are unable to maintain synchronous deformation under bending, twisting, or stretching, thereby limiting their application potential. Liquid metal (LM), with its exceptional conductivity, flexibility, thermal self‐healing properties, and unique effects, presents a compelling alternative as conductive heat‐transfer material. By integrating LM TEGs can achieve stretchability, capabilities, enhance conductivity encapsulating materials (ECMs), reduce interfacial contact resistance, improve overall performance. This article provides comprehensive review cutting‐edge intersection between encompassing applications in interconnects (INCs), heat‐conductive fabrication legs. Subsequently, effects at liquid–liquid interfaces gallium commonly used LMs reviewed. Additionally, emerging process fabricating (TEMs) using LM‐printed semiconductors is explored. Finally, based on an evaluation latest advancements this field, challenges promising directions for future research discussed.

Язык: Английский

Процитировано

0

Tumor‐Targeted Catalytic Immunotherapy DOI Open Access

En‐Li Yang,

Wuyin Wang, Yingqi Liu

и другие.

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Дек. 15, 2024

Cancer immunotherapy holds significant promise for improving cancer treatment efficacy; however, the low response rate remains a considerable challenge. To overcome this limitation, advanced catalytic materials offer potential in augmenting by modulating immunosuppressive tumor microenvironment (TME) through precise biochemical reactions. Achieving optimal targeting precision and therapeutic efficacy necessitates thorough understanding of properties underlying mechanisms tumor-targeted materials. This review provides comprehensive systematic overview recent advancements their critical role enhancing immunotherapy. It highlights types reactions, construction strategies materials, fundamental targeting, including passive, bioactive, stimuli-responsive, biomimetic approaches. Furthermore, outlines various tumor-specific strategies, encompassing tissue, cell, exogenous TME-responsive, cellular TME strategies. Finally, discussion addresses challenges future perspectives transitioning into clinical applications, offering insights that pave way next-generation therapies provide substantial benefits to patients settings.

Язык: Английский

Процитировано

2