International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143977 - 143977
Опубликована: Май 1, 2025
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143977 - 143977
Опубликована: Май 1, 2025
Язык: Английский
Journal of Biomaterials Science Polymer Edition, Год журнала: 2025, Номер unknown, С. 1 - 26
Опубликована: Апрель 1, 2025
The current challenge in developing wound healing dressings lies achieving antibacterial effects while avoiding cytotoxicity to cells that are crucial for the process. Addressing this challenge, Zeolitic Imidazolate Framework-67 (ZIF-67), a cobalt-containing metal-organic framework (MOF), has emerged as promising additive due cobalt's broad-spectrum antimicrobial effects. This study developed semi-interpenetrating polymer network (semi-IPN) hydrogels by incorporating 1-3 wt.% ZIF-67 into collagen-guar gum matrices, resulting biocomposites with tunable structural and functional properties. These exhibit fibrillar-granular morphology, uniform cobalt ion distribution on semi-crystalline surface, strong activity against Escherichia coli (E. coli). At 3 wt.%, accelerates gelation, strengthens crosslinking interactions, enhances storage modulus, thermal stability, hydrolytic resistance of hydrogels. Furthermore, 1 also function in-situ curcumin delivery systems, offering controlled release under physiological conditions significant biodegradation presence collagenase. In vitro tests demonstrate chemical composition these hydrogels, regardless content, effectively supports monocyte fibroblast metabolic activity, promotes cell proliferation, increases interleukin-10 (IL-10) secretion human monocytes. Additionally, absence hemolytic blood further underscores safety suitability hydrogel advanced treatment applications.
Язык: Английский
Процитировано
0Materials Today Sustainability, Год журнала: 2025, Номер unknown, С. 101102 - 101102
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Colloids and Surfaces B Biointerfaces, Год журнала: 2025, Номер unknown, С. 114714 - 114714
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0RSC Advances, Год журнала: 2025, Номер 15(17), С. 13453 - 13467
Опубликована: Янв. 1, 2025
Illustration of the mechanism TiO 2 -HAP nanocomposite with multifunctional properties for potential application in early caries.
Язык: Английский
Процитировано
0International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 143977 - 143977
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
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