Cyborg and Bionic Systems,
Год журнала:
2024,
Номер
5
Опубликована: Янв. 1, 2024
In
the
realm
of
precise
medicine,
advancement
manufacturing
technologies
is
vital
for
enhancing
capabilities
medical
devices
such
as
nano/microrobots,
wearable/implantable
biosensors,
and
organ-on-chip
systems,
which
serve
to
accurately
acquire
analyze
patients’
physiopathological
information
perform
patient-specific
therapy.
Electrospinning
holds
great
promise
in
engineering
materials
components
advanced
devices,
due
demonstrated
ability
advance
development
nanomaterial
science.
Nevertheless,
challenges
limited
composition
variety,
uncontrollable
fiber
orientation,
difficulties
incorporating
fragile
molecules
cells,
low
production
effectiveness
hindered
its
further
application.
To
overcome
these
challenges,
electrospinning
techniques
have
been
explored
manufacture
functional
composites,
orchestrated
structures,
living
constructs,
scale-up
fabrication.
This
review
delves
into
recent
advances
underscores
their
potential
revolutionizing
field
upon
introducing
fundamental
conventional
techniques,
well
discussing
current
future
perspectives.
Advanced Functional Materials,
Год журнала:
2022,
Номер
32(20)
Опубликована: Фев. 14, 2022
Abstract
The
growing
use
of
plastic
materials
has
led
to
the
continuous
accumulation
wastes
in
marine
environments,
which
fragment
into
hazardous
micro‐and
nanoplastics.
These
particles
absorb
toxic
organic
pollutants
on
their
surface,
support
bacterial
biofilms
growth,
and
propagate
through
food
chain,
posing
serious
risks
for
human
health.
Therefore,
nano/microplastics
pollution
become
a
global
issue,
making
definitive
elimination
compulsory.
Self‐propelled
nano/microrobots
have
demonstrated
efficient
removal
from
water,
combining
enhanced
physicochemical
properties
nano/microscale
active
motion.
During
last
year,
potential
this
technology
degrade
been
investigated.
Here,
most
advanced
strategies
capture
subsequent
degradation
by
autonomous
are
critically
reviewed.
A
short
introduction
main
propulsion
mechanisms
experimental
techniques
studying
is
also
provided.
Forthcoming
challenges
research
field
discussed
proactively.
This
perspective
inspires
future
nano/microrobotic
designs
approaches
water
purification
other
emerging
pollutants.
ACS Nano,
Год журнала:
2022,
Номер
16(6), С. 8694 - 8703
Опубликована: Май 4, 2022
Titanium
dental
implants
are
a
multibillion
dollar
market
in
the
United
States
alone.
The
growth
of
bacterial
biofilm
on
implant
can
cause
gingivitis,
loss,
and
expensive
subsequent
care.
Herein,
we
demonstrate
efficient
eradication
titanium
via
swarming
magnetic
microrobots
based
ferromagnetic
(Fe3O4)
photoactive
(BiVO4)
materials
through
polyethylenimine
micelles.
component
serves
as
propulsion
force
using
transversal
rotating
field
while
BiVO4
is
generator
reactive
oxygen
species
to
eradicate
colonies.
Such
magnetically
powered,
precisely
navigated
able
destroy
colonies
implants,
demonstrating
their
use
precision
medicine.
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(21), С. 9127 - 9173
Опубликована: Янв. 1, 2022
Bioadhesive
materials
are
promising
candidates
for
sealing
wounds
as
replacements
suturing
and
stapling
techniques.
Design
of
biomaterials
involves
introducing
adhesive
functionality
into
tough
polymer
networks.
Micro/nanoplastic
(MNP)
contamination
in
nonmarine
waters
has
evolved
into
a
notable
ecotoxicological
threat
to
the
global
ecosystem.
However,
existing
strategies
for
MNP
removal
are
typically
limited
chemical
flocculation
or
physical
filtering
that
often
fails
decontaminate
plastic
particulates
with
ultrasmall
sizes
ultralow
concentrations.
Here,
we
report
self-driven
magnetorobot
comprising
magnetizable
ion-exchange
resin
sphere
can
be
used
dynamically
remove
separate
MNPs
from
waters.
As
result
of
long-range
electrophoretic
attraction
established
by
recyclable
resin,
shows
sustainable
efficiency
>90%
over
100
treatment
cycles,
verified
broad
applicability
varying
compositions,
sizes,
and
shapes
as
well
water
samples.
Our
work
may
facilitate
industry-scale
affordable
cost
minimal
secondary
pollution
suggests
an
appealing
strategy
based
on
self-propelled
micro/nanorobots
sample
assess
nanoplastics
aqueous
environment.
Cyborg and Bionic Systems,
Год журнала:
2022,
Номер
2022
Опубликована: Янв. 1, 2022
The
rapid
development
of
medical
micromotors
draws
a
beautiful
blueprint
for
the
noninvasive
or
minimally
invasive
diagnosis
and
therapy.
By
combining
stimuli-sensitive
hydrogel
materials,
are
bestowed
with
new
characteristics
such
as
stimuli-responsive
shape
transformation/morphing,
excellent
biocompatibility
biodegradability,
drug
loading
ability.
Actuated
by
chemical
fuels
external
fields
(e.g.,
magnetic
field,
ultrasound,
light,
electric
field),
hydrogel-based
(HBSR)
can
be
utilized
to
load
therapeutic
agents
into
networks
directly
grip
target
cargos
drug-loaded
particles,
cells,
thrombus),
transport
them
sites
interest
tumor
area
diseased
tissues),
unload
execute
specific
task
cell
capture,
targeted
sampling,
removal
blood
clots)
in
response
stimulus
change
temperature,
pH,
ion
strength,
chemicals)
physiological
environment.
high
flexibility,
adaptive
capacity,
morphing
property
enable
HBSR
complete
tasks
complex
scenarios,
especially
confined,
hard-to-reach
tissues,
vessels
body.
Herein,
this
review
summarizes
current
progress
stimuli
responsiveness.
thermo-responsive,
photothermal-responsive,
magnetocaloric-responsive,
pH-responsive,
ionic-strength-responsive,
chemoresponsive
discussed
detail.
Finally,
challenges
future
perspectives
biomedical
field
discussed.
ACS Nano,
Год журнала:
2023,
Номер
17(15), С. 14196 - 14204
Опубликована: Июль 26, 2023
Microrobots
are
being
explored
for
biomedical
applications,
such
as
drug
delivery,
biological
cargo
transport,
and
minimally
invasive
surgery.
However,
current
efforts
largely
focus
on
proof-of-concept
studies
with
nontranslatable
materials
through
a
"design-and-apply"
approach,
limiting
the
potential
clinical
adaptation.
While
these
have
been
key
to
advancing
microrobot
technologies,
we
believe
that
distinguishing
capabilities
of
microrobots
will
be
most
readily
brought
patient
bedsides
"design-by-problem"
which
involves
focusing
unsolved
problems
inform
design
practical
capabilities.
As
outlined
below,
propose
translation
accelerated
by
judicious
choice
target
improved
delivery
considerations,
rational
selection
translation-ready
biomaterials,
ultimately
reducing
burden
enhancing
efficacy
therapeutic
drugs
difficult-to-treat
diseases.