ACS Omega,
Год журнала:
2024,
Номер
9(46), С. 45673 - 45687
Опубликована: Ноя. 7, 2024
Inorganic
layered
compounds
are
an
important
part
of
organic-inorganic
functional
nanocomposites
and
offer
plentiful
opportunities
possibilities
for
synthesizing
new-style
multifunctional
materials
because
they
could
be
intercalated,
exfoliated,
swollen.
In
recent
years,
as
inorganic
with
photoluminescence,
rare
earth
hydroxides
(LRHs)
have
been
extensively
studied.
Due
to
their
rich
functionalization
ways,
applied
or
shown
potential
application
value
in
many
fields
such
pollution
detection,
biomedicine,
photoelectric
energy
storage,
so
on.
On
account
the
basic
physical
chemical
properties,
structures
LRHs
may
regulated
through
exfoliation
intercalation,
which
provides
more
new
composite
broadening
updating
fields.
this
paper,
extracted
from
compounds,
structure,
synthesis,
research
progress,
summarized
detail,
lays
a
great
theoretical
foundation
further
exploration
optimization
material
industry,
medicine,
optoelectronics,
other
Advanced Functional Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 9, 2024
Abstract
It
is
important
but
challenging
to
innovate
inorganic
sonosensitizers
with
controlled
biodegradability
and
enhanced
sonodynamic
chemodynamic
activities
harness
remodel
the
immunosuppressive
tumor
microenvironment
(TME)
for
awakening
robust
immune
responses
against
metastatic
cancers.
Herein
rational
design
defect
engineering
strategy
of
a
pH‐responsive
biodegradable
sonozyme
system
in
sulfide
nanocages
augmented
cancer
immunotherapy
reported.
A
series
highly
defective
Co
9
S
8‐x
elevated
sulfur‐vacancy
(V
)
levels
are
fabricated
systematically
explore
V
‐dependent
properties
by
regulating
weight
ratio
sulfur
cobalt
source.
The
bandgap
substantially
reduced
from
2.06
1.54
eV,
atomic
2+
3+
increased
1.53
1.97.
Therefore,
sonodynamic,
chemodynamic,
antitumor
dramatically
system.
slow
degradation
slightly
acid
TME
size
targeting
infiltration,
while
exerting
slight
influence
on
performance.
As
result,
satisfactory
therapeutic
effects
eradication
primary,
distant,
tumors
can
be
achieved.
This
work
highlights
potential
strategies
combating
Nature Communications,
Год журнала:
2024,
Номер
15(1)
Опубликована: Авг. 30, 2024
Hydrogen
sulfide
is
essential
in
numerous
physiological
and
pathological
processes
has
emerged
as
a
promising
cancer
imaging
signaling
molecule
potentially
versatile
therapeutic
agent.
However,
the
endogenous
levels
of
hydrogen
remain
insufficient
to
perform
its
biological
functions,
thus,
developing
novel
strategies
that
amplify
signals
at
lesion
sites
increasing
interest.
In
this
work,
nanoplatform
(SNP)
based
on
sulfide-responsive
self-immolative
poly(thiocarbamate)
with
localized
signal
amplification
capability
developed
encapsulate
fluorescent
probe
(e.g.,
hemicyanine
dye;
p-Cy)
or
an
anticancer
prodrug
doxorubicin;
p-DOX)
form
nanoprobe
(SNP
Abstract
Electrically
driven
host‐dopant
structure,
such
as
single
Ga‐doped
ZnO
microwire,
is
promising
for
miniaturized
light
sources.
However,
the
electroluminescence
(EL)
a
fixed
concentration
of
Ga
dopant
barely
vary
micro/nanostructure,
limiting
their
applications
in
integrated
optoelectronics.
Here
X‐ray
irradiation
reported
simple
and
effective
post‐treatment
to
tailor
EL
intensity
color
coordinate
microwires.
After
irradiating
microwires
under
an
dose
180
Gy,
green
increases
by
≈12
times,
accompanied
narrowed
spectrum
linewidth.
Meanwhile,
shifts
from
(0.309,
0.416)
pristine
(0.319,
0.503)
irradiated
ones,
corresponding
more
purified
emission.
The
monotonically
(>20
times)
with
further
increments
doses,
intense
irradiations
shift
center
toward
green‐yellow
spectral
region
total
average
redshift
≈30±6
nm
achieved.
density
functional
theory
(DFT)
simulations
suggest
that
variation
may
stem
substitution
host
Zn
atoms
interstitial
stimulated
high‐energy
X‐ray.
These
presented
results
indicate
potential
strategy
emitters
practical
applications.
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 30, 2025
Abstract
Extracellular
matrix
(ECM),
a
core
member
of
tumor
microenvironment,
is
≈1.5‐fold
harder
than
the
surrounding
normal
tissues.
Regulating
stiffness
ECM
can
significantly
impact
physiological
activities
cells,
such
as
growth,
differentiation,
and
migration.
Herein,
sonopiezoelectric‐response
nanoplatform
consisting
Cu
3
BiS
nanospheres
(CBS
NSs)
constructed
for
remodeling.
Sonopiezoelectric
therapy
(SPT)
chemodynamic
(CDT)
are
conducted
using
ultrasound
(US)
near‐infrared
irradiation.
Under
US
irradiation,
mechanical
strain
CBS
NSs
causes
piezoelectric
polarization
promotes
redox
reaction
through
energy
band
bending.
The
built‐in
electric
field
generated
by
irradiation
amplifies
efficiency
Fenton‐like
substantially
enhances
reactive
oxygen
species
production.
Moreover,
property‐mediated
electrical
signals
allow
Ca
2+
influx,
upregulating
levels
metalloproteinase
(MMP)‐2
MMP‐9.
Integrating
with
generates
localized
heat,
which
effectively
denature
collagen,
reduce
stiffness,
enhance
permeability
into
solid
tumors,
thus
improving
SPT
effect.
combination
MMP
upregulation
collagen
degradation
maximize
benefits
remodeling
synergistically
cancer
therapeutic
efficacy
SPT/CDT.
This
SPT/CDT
synergistic
platform
an
innovative
strategy
therapy.
