A cysteine-activated fluorescent H2S donor for visualizing H2S release and alleviating cellular inflammation DOI

Nianwei Wang,

Xuan Wang,

Jicheng Wang

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

We developed a Cys-activated fluorescent H 2 S donor, Bcy-NCS, which releases and enables visualization through fluorescence changes, while also alleviating cellular inflammation.

Язык: Английский

Targeted codelivery of nitric oxide and hydrogen sulfide for enhanced antithrombosis efficacy DOI
Weiliang Deng,

Zhixin Xu,

Hua Tong

и другие.

Bioactive Materials, Год журнала: 2025, Номер 48, С. 29 - 42

Опубликована: Фев. 13, 2025

Язык: Английский

Процитировано

1
Near‐Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer DOI Creative Commons
Jinghua Li,

Juqing Gu,

Liangxuan Ding

и другие.

Aggregate, Год журнала: 2025, Номер unknown

Опубликована: Апрель 6, 2025

ABSTRACT Hepatectomy is a critical treatment for liver cancer, but achieving complete tumor removal remains challenging. The development of tumor‐targeting probes capable accurately identifying locations and providing real‐time intraoperative navigation significant clinical importance. We synthesize tumor‐targeted probe by conjugating fibroblast activation protein inhibitor (FAPI) with near‐infrared organic room temperature phosphorescence (RTP) material. then analyze its surgical performance in the cancer model imaging fresh patient‐derived samples. In vivo validation reveals that exhibits optimal intensity within 48 h (8.53 × 10 5 p s −1 cm −2 sr ) an average signal‐to‐noise ratio 16. could effectively identify FAP‐positive samples from patients. successful application phosphorescence‐guided surgery suggests RTP holds translational value serve as auxiliary tool cancer.

Язык: Английский

Процитировано

0
A Tumor Heterogeneity-Independent Antigen-Responsive Nanocarrier Enabled by Bioorthogonal Pre-Targeting and Click-Activated Self-Immolative Polymer DOI

Ye Liu,

Qingyu Zong,

Yalan Tu

и другие.

Biomaterials, Год журнала: 2025, Номер 319, С. 123200 - 123200

Опубликована: Фев. 19, 2025

Язык: Английский

Процитировано

0
In vivo monitoring of endogenous hydrogen sulfide and evaluation of natural protectants in liver injury mice using a highly selective bioluminescent probe DOI
Chong Hu,

Zeping Yang,

Xiaorui Shi

и другие.

Biosensors and Bioelectronics, Год журнала: 2025, Номер 278, С. 117343 - 117343

Опубликована: Март 5, 2025

Язык: Английский

Процитировано

0
Mutually reinforced activatable NIR fluorescence/MR bimodal imaging enabled by tumor-specific biomarker amplification DOI Creative Commons

Maolin Jiang,

Ye Liu, Kewei Wang

и другие.

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Future applications of self-immolative polymers in drug delivery DOI
Elizabeth R. Gillies

Expert Opinion on Drug Delivery, Год журнала: 2025, Номер unknown

Опубликована: Апрель 11, 2025

Язык: Английский

Процитировано

0
A cysteine-activated fluorescent H2S donor for visualizing H2S release and alleviating cellular inflammation DOI

Nianwei Wang,

Xuan Wang,

Jicheng Wang

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

We developed a Cys-activated fluorescent H 2 S donor, Bcy-NCS, which releases and enables visualization through fluorescence changes, while also alleviating cellular inflammation.

Язык: Английский

Процитировано

0