Cited by A one-pot Synthesis of 2,3-Dihydrobenzofurans, Benzofuran-2(3H)-ones, and Indoles via [4 + 1] Annulation Reaction of ortho-substituted para-Quinone Methides and Bromonitromethane

1,6-Conjugate addition of in situ generated aryldiazenes to p-quinone methides DOI

Ajay G. Mamale,

Sayantan Paul,

Rajesh G. Gonnade

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(27), С. 5636 - 5645

Опубликована: Янв. 1, 2024

Herein we report a transition-metal free, base-mediated 1,6-conjugate addition of aryldiazenes to para -quinone methides ( p -QMs).

Язык: Английский

Процитировано

Metal free, one pot 1,6‐Conjugate Addition of Diol on para‐Quinone Methide followed by ipso cyclization: An Approach to Spiro 1,4‐Dioxane cyclohexadienone Derivatives DOI

Ramesh A. Gaikwad,

Sumit B. Kamble,

Suresh B. Waghmode

и другие.

Chemistry - An Asian Journal, Год журнала: 2022, Номер 17(24)

Опубликована: Окт. 19, 2022

A novel one-pot transition metal-free and Brönsted acid mediated 1,6-conjugate addition of bisnuleophilic diol on biselectrophilc para-quinone methide followed by ipso cyclization assisted NBS has been developed under mild reaction conditions, offers a new approach to synthesize spiro 1,4-dioxane cyclohexadienone derivatives. This strategy features broad substrate scope p-QMs with high functional group tolerance good yields spirocyclic scaffolds (60-92 %). N-Bromo succinimide an important role in spirocyclization efficiency.

Язык: Английский

Процитировано

Cu(I)-Catalyzed Three-Component Annulation for the Synthesis of 3-Acyl Imidazo[1, 5-a]Pyridines from 2-Pyridinyl-Substituted p-Quinone Methides, Terminal Alkynes, and TsN₃ Using O₂ as the Oxygen Source DOI

Yan Chen, Yuan‐Ting Zhang, Kun‐Peng Wang

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(8), С. 5423 - 5433

Опубликована: Апрель 1, 2024

Currently, most conventional methods to achieve imidazo[1,5-a]pyridines have limitations for the synthesis of 3-acyl imidazo[1,5-a]pyridines. Herein, a novel and efficient Cu(I)-catalyzed three-component annulation method valuable by reaction 2-pyridinyl-substituted p-QMs, terminal alkynes, TsN3 in presence O2 under mild conditions successfully been developed. The investigation indicated that molecular oxygen (O2) TsN3, respectively, serving as nitrogen sources, were essential successful completion system.

Язык: Английский

Процитировано

Domino Approach to Heterocycles-Based Unsymmetrical Triarylmethanes through Heteroannulation of 2-(2-Enynyl)-pyridines with Enaminones DOI

Feroz Ahmad,

Pavit K. Ranga,

Shaheen Fatma

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(17), С. 12104 - 12117

Опубликована: Авг. 13, 2024

Herein, we report a copper-catalyzed protocol to access unsymmetrical triarylmethanes containing both indolizine and the chromone scaffolds in same molecule via 5-endo-dig cyclization of 2-(2-enynyl)-pyridines followed by reaction with 2-hydroxyaryl enaminones. A variety enaminones were subjected under optimal conditions, respective obtained good excellent yields.

Язык: Английский

Процитировано

A one-pot Synthesis of 2,3-Dihydrobenzofurans, Benzofuran-2(3H)-ones, and Indoles via [4 + 1] Annulation Reaction of ortho-substituted para-Quinone Methides and Bromonitromethane DOI

Amol T. Savekar,

Vishal B. Karande,

Dattatray G. Hingane

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

A facile one-pot synthesis of oxygen- and nitrogen-containing benzoheterocycles has been achieved through [4 + 1] annulation para -quinone methides, followed by an oxidation/elimination sequence.

Язык: Английский

Процитировано